CAS Chem.name Chem.SMILES #CA_without_S9 #Obs_CA_with_S9 Bioassay - Reference(s) - 598-55-0 Methyl carbamate COC(N)=O negative negative in Vitro Mammalian Chromosome Aberration Test "Anderson B., et al., Environmental Mol. Mutag., 16(18), 55-137, 1990." 51-79-6 Ethyl carbamate CCOC(N)=O negative negative in Vitro Mammalian Chromosome Aberration Test "National Toxicology Program (1996). Urethane in Drinking Water and Urethane in 5% Ethanol Administered To F344/N R ats and B6C3F1 Mice. (NTP Technical Report on Toxicity Studies No. 52), Research Triangle Park, NC" 50-07-7 mitomycin CC1=C(N)C(=O)C2C(COC(N)=O)C3(OC)C4C(CN3C=2C1=O)N4 positive positive in Vitro Mammalian Chromosome Aberration Test "Sofuni, T., Ed. (1998). Data Book of Chromosomal Aberration Test in vitro, Revised Edition. Life-Science Information Center, Tokyo, Japan" 63-25-2 carbaryl CNC(=O)Oc1cccc2ccccc12 positive positive in Vitro Mammalian Chromosome Aberration Test "Sofuni, T., Ed. (1998). Data Book of Chromosomal Aberration Test in vitro, Revised Edition. Life-Science Information Center, Tokyo, Japan" 27636-33-5 Naphthyl N-methylcarbamate CNC(=O)Oc1cccc2ccccc12 positive positive in Vitro Mammalian Chromosome Aberration Test "Ishidate M. Jr., S. Odashima S., Mutation Res., 48, 337-354, 1977." 1129-41-5 3-Methylphenyl_N-methylcarbamate Cc1cccc(OC(=O)NC)c1 positive positive in Vitro Mammalian Chromosome Aberration Test "Sofuni, T., Ed. (1998). Data Book of Chromosomal Aberration Test in vitro, Revised Edition. Life-Science Information Center, Tokyo, Japan" 2425-10-7 "Phenol, 3,4-dimethyl-, methylcarbamate; Xylylcarb" Cc1ccc(OC(=O)NC)cc1C positive positive in Vitro Mammalian Chromosome Aberration Test "Sofuni, T., Ed. (1998). Data Book of Chromosomal Aberration Test in vitro, Revised Edition. Life-Science Information Center, Tokyo, Japan" 9041-93-4 Bleomycin sulfate CC(C(O)C(C)C(=O)NC(C(C)O)C(=O)NCCC1=NC(C2=NC(C(=O)NCCCS{+}(C)(C).O{-}S(O)(=O)=O)=CS2)=CS1)NC(=O)C(C(C1=CNC=N1)OC{P-}1C{P-}(OC{P+}2C{P-}(O)C{P-}(OC(N)=O)C{P+}(O)C{P-}(CO)O2)C{P-}(O)C{P+}(O)C{P+}(CO)O1)NC(=O)c1c(C)c(N)nc(C(CC(N)=O)NCC(N)C(N)=O)n1 positive positive in Vitro Mammalian Chromosome Aberration Test "Sofuni, T., Ed. (1998). Data Book of Chromosomal Aberration Test in vitro, Revised Edition. Life-Science Information Center, Tokyo, Japan" 10605-21-7 Carbendazim COC(=O)NC1Nc2ccccc2N=1 positive positive in Vitro Mammalian Chromosome Aberration Test "U.S. Environmental Protection Agency, March, 2011 Hazard Characterization Document, SCREENING-LEVEL HAZARD CHARACTERIZATION Carbamic acid, 1H-benzimidazol-2-yl, methyl ester (CASRN 10605-21-7)" 1563-66-2 Carbofuran CC1(C)Cc2cccc(OC(=O)NC)c2O1 positive positive in Vitro Mammalian Chromosome Aberration Test "Soloneski S, Reigosa MA, et al. (2008). Genotoxic and cytotoxic effects of carbofuran and furadan on Chinese hamster ovary (CHOK1) cells. Mutat. Res. 656 (1-2): 68-73." 23103-98-2 Pirimicarb Cc1c(C)c(OC(=O)N(C)C)nc(N(C)C)n1 positive positive in Vitro Mammalian Chromosome Aberration Test "Soloneski S., M. Larramendy, Journal of Hazardous Mater., 174(1-3), 410-415, 2010." 589-41-3 N-Hydroxyurethane CCOC(=O)NO positive positive in Vitro Mammalian Chromosome Aberration Test "Borenfreund E., Krim M., Bendich A., Chromosomal aberrations induced by hyponitrile and hydroxylamine derivatives, J. Natl. Cancer Inst., 1964, 32(3), 667-679." 11056-06-7 bleomycin CC(C(O)C(C)C(=O)NC(C(C)O)C(=O)NCCC1=NC(C2=NC(C(=O)NCCCS{+}(C)C)=CS2)=CS1)NC(=O)C(C(C1=CN=CN1)OC1C(OC2C(O)C(OC(N)=O)C(O)C(CO)O2)C(O)C(O)C(CO)O1)NC(=O)c1c(C)c(N)nc(C(CC(N)=O)NCC(N)C(N)=O)n1 positive positive in Vitro Mammalian Chromosome Aberration Test P. Maier and W. Schmid; Ten model mutagens evaluated by the micronucleus test; Mut. Res. 40 (1976) 325-338 16752-77-5 Methomyl CC(=NOC(=O)NC)SC positive positive in Vitro Mammalian Chromosome Aberration Test "L.Y. Wei, J.S. Chao, and C.C. Hong, Assessment of the Ability of Propoxur, Methomyl, and Aldicarb, Three Carbamate Insecticides, to Induce Micronuclei In Vitro in Cultured Chinese Hamster Ovary Cells and In Vivo in BALB/c Mice, Environmental and Molecular Mutagenesis 29:386–393 (1997)" 114-26-1 Propoxur CC(C)Oc1ccccc1OC(=O)NC positive positive in Vitro Mammalian Chromosome Aberration Test "L.Y. Wei, J.S. Chao, and C.C. Hong, Assessment of the Ability of Propoxur, Methomyl, and Aldicarb, Three Carbamate Insecticides, to Induce Micronuclei In Vitro in Cultured Chinese Hamster Ovary Cells and In Vivo in BALB/c Mice, Environmental and Molecular Mutagenesis 29:386–393 (1997)" 116-06-3 Aldicarb CC(C)(C=NOC(=O)NC)SC positive positive in Vitro Mammalian Chromosome Aberration Test "L.Y. Wei, J.S. Chao, and C.C. Hong, Assessment of the Ability of Propoxur, Methomyl, and Aldicarb, Three Carbamate Insecticides, to Induce Micronuclei In Vitro in Cultured Chinese Hamster Ovary Cells and In Vivo in BALB/c Mice, Environmental and Molecular Mutagenesis 29:386–393 (1997)"