CAS Chem.name Chem.SMILES #CA_without_S9 #Obs_CA_with_S9 Bioassay - Reference(s) - 105-16-8 2-propenoic acid, 2-methyl-, 2-(diethylamino)ethyl ester CCN(CC)CCOC(=O)C(C)=C negative positive in Vitro Mammalian Chromosome Aberration Test NIHS Japan 96-33-3 Methyl Acrylate COC(=O)C=C positive positive in Vitro Mammalian Chromosome Aberration Test Sofuni, T., Ed. (1998). Data Book of Chromosomal Aberration Test in vitro, Revised Edition. Life-Science Information Center, Tokyo, Japan 108-31-6 Maleic Anhydride O=C1C=CC(=O)O1 positive positive in Vitro Mammalian Chromosome Aberration Test Sofuni, T., Ed. (1998). Data Book of Chromosomal Aberration Test in vitro, Revised Edition. Life-Science Information Center, Tokyo, Japan 140-88-5 Ethyl Acrylate CCOC(=O)C=C positive positive in Vitro Mammalian Chromosome Aberration Test Sofuni, T., Ed. (1998). Data Book of Chromosomal Aberration Test in vitro, Revised Edition. Life-Science Information Center, Tokyo, Japan 585-07-9 tert-Butylmethacrylate CC(=C)C(=O)OC(C)(C)C positive positive in Vitro Mammalian Chromosome Aberration Test NIHS Japan 868-77-9 2-methyl-2-propenoic_acid,_2-hydroxyethyl_ester CC(=C)C(=O)OCCO positive positive in Vitro Mammalian Chromosome Aberration Test NIHS Japan 2439-35-2 2-(Dimethylamino) Ethyl Acrylate CN(C)CCOC(=O)C=C positive positive in Vitro Mammalian Chromosome Aberration Test NIHS Japan 623-91-6 diethyl_maleate CCOC(=O)C=CC(=O)OCC positive positive in Vitro Mammalian Chromosome Aberration Test NIHS Japan 27813-02-1 Methacrylic acid, monoester with propane-1,2-diol CC(O)COC(=O)C(C)=C positive positive in Vitro Mammalian Chromosome Aberration Test NIHS Japan 2867-47-2 N,N-Dimethylaminoethyl methacrylate CC(=C)C(=O)OCCN(C)C positive positive in Vitro Mammalian Chromosome Aberration Test NIHS Japan 5039-78-1 (2-(Methacryloyloxy)ethyl)trimethylammonium CC(=C)C(=O)OCCN{+}(C)(C)(C).Cl{-} positive positive in Vitro Mammalian Chromosome Aberration Test NIHS Japan 79-10-7 Acrylic Acid C=CC(O)=O positive positive in Vitro Mammalian Chromosome Aberration Test McCarthy, K.L., Thomas, W.C., Aardema, M.J., Seymour, J.L., Putman, D.L., Yang, L.L., Curren, R.D., Valencia, R., Genetic toxicology of acrylic acid. Food Chem. Toxicol., 1992, 30(6), 505-515. Danish EPA Inventory, Sofuni, T., Ed. (1998). Data Book of Chromosomal Aberration Test In Vitro, Revised Edition. Life-Science Information Center; Tokyo, Japan. 80-62-6 Methyl Methacrylate CC(=C)C(=O)OC positive positive in Vitro Mammalian Chromosome Aberration Test National Toxicology Program, Technical Report Series No. 314, Toxicology and Carcinogenesis Studies Of Methyl Methacrylate (CASNo. 80-62-6) In F344/N Rats and B6C3FT Mice 97-90-5 Ethylene methacrylate CC(=C)C(=O)OCCOC(=O)C(C)=C positive positive in Vitro Mammalian Chromosome Aberration Test F. R. Johansen et. al. Regulatory Toxicology and Pharmacology 50 (2008) 322-335. 103-11-7 Ethylhexyl Acrylate CCCCC(CC)COC(=O)C=C positive positive in Vitro Mammalian Chromosome Aberration Test F. R. Johansen et. al. Regulatory Toxicology and Pharmacology 50 (2008) 322-335. 109-16-0 Triethylene glycol dimethacrylate CC(=C)C(=O)OCCOCCOCCOC(=O)C(C)=C positive positive in Vitro Mammalian Chromosome Aberration Test F. R. Johansen et. al. Regulatory Toxicology and Pharmacology 50 (2008) 322-335. 141-32-2 N-butyl acrylate CCCCOC(=O)C=C positive positive in Vitro Mammalian Chromosome Aberration Test F. R. Johansen et. al. Regulatory Toxicology and Pharmacology 50 (2008) 322-335. 2223-82-7 2,2-Dimethyltrimethylene acrylate CC(C)(COC(=O)C=C)COC(=O)C=C positive positive in Vitro Mammalian Chromosome Aberration Test F. R. Johansen et. al. Regulatory Toxicology and Pharmacology 50 (2008) 322-335. 15625-89-5 Acrylic_acid_2,2-bis-acryloyloxymethyl-butyl_ester CCC(COC(=O)C=C)(COC(=O)C=C)COC(=O)C=C positive positive in Vitro Mammalian Chromosome Aberration Test F. R. Johansen et. al. Regulatory Toxicology and Pharmacology 50 (2008) 322-335. 999-61-1 propylene glycol monoacrylate CC(O)COC(=O)C=C positive positive in Vitro Mammalian Chromosome Aberration Test F. R. Johansen et. al. Regulatory Toxicology and Pharmacology 50 (2008) 322-335. 1680-21-3 2-propenoic acid, 1,2-ethanediylbis(oxy-2,1-etha C=CC(=O)OCCOCCOCCOC(=O)C=C positive positive in Vitro Mammalian Chromosome Aberration Test F. R. Johansen et. al. Regulatory Toxicology and Pharmacology 50 (2008) 322-335. 96-05-9 2-propenoic acid, 2-methyl-, 2-propen-1-yl ester CC(=C)C(=O)OCC=C positive positive in Vitro Mammalian Chromosome Aberration Test Elf Atochem, 1991, Chrmosomal Aberration assay with Allyl Metacrylate using Human Lymphosytes. Report No. CIT 7330. SIAM 10, Screening Information Data Base (SIDS). Available from: http://www.chem.unep/ch/irptc/sids/OECDSIDS/sidspub.html. 68586-19-6 Dicyclopentenyloxyethylmethacrylate CC(=C)C(=O)OCC(OC1CCCC=1)O/C1CCC\C=1 positive positive in Vitro Mammalian Chromosome Aberration Test F. R. Johansen et. al. Regulatory Toxicology and Pharmacology 50 (2008) 322-335. 818-61-1 2-Hydroxyethyl acrylate C=CC(=O)OCCO positive positive in Vitro Mammalian Chromosome Aberration Test JAPAN CHEMICAL INDUSTRY ECOLOGY-TOXICOLOGY & INFORMATION CENTER (JETOC), JAPAN; MUTAGENICITY TEST DATA OF EXISTING CHEMICAL SUBSTANCES BASED ON THE TOXICITY INVESTIGATION SYSTEM OF THE INDUSTRIAL SAFETY AND HEALTH LAW, SUPPLEMENT 3; 2005 107-02-8 Acrolein C=CC=O positive positive in Vitro Mammalian Chromosome Aberration Test Ishidate, M., M. C. Harnois, T. Sofuni, A Comparative Analysis of Data on the Clastogenicity of 951 Chemical Substances Tested in Mammalian Cell Cultures, Mutat. Res. 195 (1988), 151 – 213 106-91-2 Glycidyl methacrylate CC(=C)C(=O)OCC1CO1 positive positive in Vitro Mammalian Chromosome Aberration Test NIHS Japan