CAS Chem.name Chem.SMILES #Observed Mutagenicity Bioassay - Reference(s) - 503-30-0 1,3-Epoxypropane; 1,2-propylene oxide C1CCO1 in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) P&G Inventory 557-11-9 Allyl urea C=CCNC(N)=O in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) P&G Inventory 57-06-7 1-Propene, 3-isothiocyanato-; C=CCN=C=S in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Neudecker, T. and Henschler, D.; Allyl isothiocyanate is mutagenic in salmonella typhimurium; Mutat. Res. 156(1-2):33-37, 1985 2303-17-5 Tri-allate CC(C)N(C(C)C)C(=O)SCC(Cl)=C(Cl)Cl in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Mutation Research, 168 (1986) 69-240 18829-55-5 2-Heptenal CCCC/C=C/C=O in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Eder, E., Deininger, C., Neudecker, T. and Deininger, D.; Mutagenicity of Beta-Alkyl Substituted Acrolein Congeners in the Salmonella Typhimurium Strain TA100 and Genotoxicty Testing in The SOS Chromotest; Environ. Mol. Mutagen. 19(4):338-345, 1992 4635-87-4 3-Pentenenitrile CC=CCC#N in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) P&G Inventory 123-73-9 trans-Crotonaldehyde CC=CC=O in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) P&G Inventory 115-07-1 Propylene CC=C in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) ECHA, Registration dossier; https://echa.europa.eu/registration-dossier/-/registered-dossier/16184/7/7/2/?documentUUID=77943e00-cd2f-4544-ac16-0f395996638d 766-40-5 3,4-dichloro-5-hydroxy-2(5h)-furanone;3,4-dichloro-5-hydroxyfuran-2(5h)-one OC1C(Cl)=C(Cl)C(=O)O1 in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Lalonde, Rt And Leo, Hr; Interactive Chlorine-By-Bromine And Hydrogen-By-Hydroxyl Group Replacement Effects In 2(5h)-Furanone Mutagenicity; Chem. Res. Toxicol. 7(6):779-783, 1994 112309-61-2 3-chloro-4-methyl-5-hydroxy-2(5h)-furanone CC1C(O)OC(=O)C=1Cl in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Lalonde, Rt And Leo, Hr; Interactive Chlorine-By-Bromine And Hydrogen-By-Hydroxyl Group Replacement Effects In 2(5h)-Furanone Mutagenicity; Chem. Res. Toxicol. 7(6):779-783, 1994 149418-41-7 3,4-dibromo-2(5h)-furanone O=C1C(Br)=C(Br)CO1 in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Lalonde, Rt And Leo, Hr; Interactive Chlorine-By-Bromine And Hydrogen-By-Hydroxyl Group Replacement Effects In 2(5h)-Furanone Mutagenicity; Chem. Res. Toxicol. 7(6):779-783, 1994 107-02-8 Acrolein C=CC=O in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Parent, Ra, Caravello, He And San, Rhc; J. Appl. Toxicol. 16(2):103-108, 1996; Waegemaekers, Thjm And Bensink, Mpm; Mutat. Res. 137(2-3):95-102, 1984 591-87-7 Allyl acetate; Acetic acid, 2-propen-1-yl ester CC(=O)OCC=C in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Auerbach, S. S., J. Mahler, Gr. S. Travlos, R. D. Irwin, A Comparative 90-Day Toxicity Study of Allyl Acetate, Allyl Alcohol and Acrolein, Toxicol. 253 (2008), 79 – 88; NTP Technical Report on the Comparative Toxicity Studies of Allyl Acetate, Allyl Alcohol, and Acrolein Administered by Gavage to F344/N Rats and B6C3F1 Mice, NTP Toxicity Report Series Number 48, July 2006; http://ntp.niehs.nih.gov/ntp/htdocs/ST_rpts/tox048.pdf 482-44-0 Pentosalen CC(C)=CCOc1c2c(cc3C=CC(=O)Oc13)C=CO2 in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Uwaifo, AO.; The Mutagenicities of Seven Coumarin Derivatives and a Furan Derivative (Nimbolide) Isolated from Three Medicinal Plants; J. Toxicol. Environ. Health 13(4-6):521-530, 1984 6728-26-3 2-Hexenal CCC/C=C\C=O in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Eder, E, Deininger, C, Neudecker, T And Deininger, D; Environ. Mol. Mutagen. 19(4):338-345, 1992 142-83-6 2,4-Hexadienal C/C=C\C=C/C=O in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Eder, E, Deininger, C, Neudecker, T And Deininger, D; nviron. Mol. Mutagen. 19(4):338-345, 1992 2608-48-2 5-(4-Nitrophenyl)-2,4-pentadienal [O-][N+](=O)c1ccc(\C=C\C=C\C=O)cc1 in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) CCRIS database,Toxnet databases *10008-88-4 N-[2-methyl-3-(phenylimino)-1-propenyl]benzenamine hydrochloride C/C(=C\Nc1ccccc1)/C=N/c1ccccc1_Cl in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html. Last visited:October, 2021. 1576-87-0 2-pentenal CC/C=C/C=O in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html. Last visited:October, 2021. 178043-48-6 3-[2,6-dichloro-4-(3,3-dichloroprop-2-enoxy)phenoxy]propan-1-ol OCCCOc1c(Cl)cc(OCC=C(Cl)Cl)cc1Cl in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html. Last visited:October, 2021. 188021-38-7 1-bromo-3-tert-butyl-5-methyl-2-prop-2-enoxybenzene Cc1cc(Br)c(OCC=C)c(C(C)(C)C)c1 in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html. Last visited:October, 2021. 426253-76-1 (2S)-4-(chloroacetyl)-2-methyl-2,5-dihydro-1H-pyrrole-1-carboxylic acid allyl ester CC{P+}1C=C(C(=O)CCl)CN1C(=O)OCC=C in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html. Last visited:October, 2021. 589-09-3 N-allylaniline C=CCNc1ccccc1 in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html. Last visited:October, 2021. 922-63-4 2-ethylacrolein CCC(=C)C=O in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html. Last visited:October, 2021. 107-11-9 Allylamine C=CCN in vitro Ames negative Bacterial Reverse Mutation Assay (e.g. Ames Test) P&G Inventory 123-68-2 Allyl hexanoate CCCCCC(=O)OCC=C in vitro Ames negative Bacterial Reverse Mutation Assay (e.g. Ames Test) ECHA Registration dossier 6728-21-8 Allyl methanesulfonate CS(=O)(=O)OCC=C in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Eder, E., Kutt, W., Deininger, C., Chem. Biol. Interact., 2001, 137(1), 89-99. doi: 10.1016/s0009-2797(01)00211-3