CAS	Chem.name	SMILES	#Observed Mutagenicity	Bioassay - 	Reference(s) -
102-96-5	beta-Nitrostyrene	[O-][N+](=O)C=Cc1ccccc1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	P&G Inventory
121-66-4	2-Amino-5-nitrothiazole	[O-][N+](=O)C1SC(=N)NC=1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	P&G Inventory; Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
139-94-6	Nithiazide	CCNC(=O)Nc1ncc(s1)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	P&G Inventory; Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
24554-26-5	N-(4-(5-Nitro-2-furyl)-2-thiazolyl)formamide	[O-][N+](=O)c1ccc(o1)-c1csc(NC=O)n1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	P&G Inventory; U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240
3688-53-7	2-(2-Furyl)-3-(5-nitro-2-furyl)acrylamide	NC(=O)C(=Cc1ccc(o1)[N+]([O-])=O)c1ccco1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	P&G Inventory; U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240
443-48-1	Metronidazole	Cc1ncc(n1CCO)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	P&G Inventory; U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240
446-86-6	Azathioprine	Cn1cnc(c1Sc1ncnc2[nH]cnc12)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	P&G Inventory; U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240
7166-19-0	beta-Bromo-beta-nitrostyrene	[O-][N+](=O)C(Br)=Cc1ccccc1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	P&G Inventory; Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
584-48-5	1-bromo-2,4-dinitrobenzene	[O-][N+](=O)c1ccc(Br)c(c1)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kerklaan, PRM, et. al.; Mutat. Res. 176(2):171-180, 1987; Gupta, Rl. et. al; Mutat. Res. 381(1):41-47, 1997
38514-71-5	anft;2-amino-4-(5-nitro-2-furyl)thiazole	Nc1nc(cs1)-c1ccc(o1)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240; CCRIS database,Toxnet databases
22994-85-0	benznidazole; 1h-imidazole-1-acetamide, 2-nitro-n-(phenylmethy	[O-][N+](=O)c1nccn1CC(=O)NCc1ccccc1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	CCRIS database,Toxnet databases
720-69-4	4,6-diamino-2-(5-nitro-2-furyl)-1,3,5-triazine	Nc1nc(N)nc(n1)-c1ccc(o1)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	CCRIS database,Toxnet databases: Rinkus, Sj And Legator, Ms; Chemical Characterization Of 465 Known Or Suspected Carcinogens And Their Correlation With Mutagenic Activity In The Salmonella Typhimurium System; Cancer Res. 39:3289-3318, 1979
33389-33-2	1,2-dihydro-2-(5-nitro-2-thienyl)quinazoline-4-(3h)-one	[O-][N+](=O)c1ccc(s1)C1NC(=O)c2ccccc2N1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	CCRIS database,Toxnet databases: Mccann, J, Choi, E, Yamasaki, E And Ames, Bn; Detection Of Carcinogens As Mutagens In The Salmonella/Microsome Test: Assay Of 300 Chemicals; PROC. NATL. ACAD. SCI. USA 72(12):5135-5139, 1975
55738-54-0	trans-2-[(dimethylamino)methylimino]-5-[2-(5-nitro-2-furyl)vinyl]-1,3,4-oxadiazo	CN(C)CN=C1NN=C(O1)C=Cc1ccc(o1)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240; NCI; The Salmonella Typhimurium/Mammalian Microsomal Assay: A Report Of The U.S. Environmental Protection Agency Gene-Tox Program; Mutat Res 168:69-240,1986
26049-69-4	2-(2,2-dimethylhydrazino)-4-(5-nitro-2-furyl)thiazole	CN(C)Nc1nc(cs1)-c1ccc(o1)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240; CCRIS database,Toxnet databases: Rinkus, Sj And Legator, Ms; Chemical Characterization Of 465 Known Or Suspected Carcinogens And Their Correlation With Mutagenic Activity In The Salmonella Typhimurium System; Cancer Res. 39:3289-3318, 1979;
551-92-8	1,2-dimethyl-5-nitroimidazole	Cc1ncc(n1C)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	CCRIS database,Toxnet databases: Vanelle, P, De Meo, Mp, Maldonado, J, Nouguier, R, Crozet, Mp, Laget, M And Dumenil, G; Genotoxicity In Oxazolidine Derivatives: Influence Of The Nitro Group; Eur. J. Med. Chem. 25(3):241-250, 1990
3570-75-0	nifurthiazole;formic acid 2-[4-(5-nitro-2-furyl)-2-thiazolyl]hydrazide	[O-][N+](=O)c1ccc(o1)-c1csc(NNC=O)n1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240
33389-36-5	Quinazoline, 4-(2-hydroxyethylamino)-2-(5-nitro-2-thienyl)-	OCCNc1nc(nc2ccccc12)-c1ccc(s1)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	CCRIS database,Toxnet databases: Mccann, J, Choi, E, Yamasaki, E And Ames, Bn; Detection Of Carcinogens As Mutagens In The Salmonella/Microsome Test: Assay Of 300 Chemicals; PROC. NATL. ACAD. SCI. USA 72(12):5135-5139, 1975
3/3/5036	1-(2-hydroxyethyl)-3-[(5-nitrofurfurylidene)amino]-2-imidazolidinone;nifurdazil	OCCN1CCN(N=Cc2ccc(o2)[N+]([O-])=O)C1=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240
19622-55-0	cl 64855	Cn1c(ncc1[N+]([O-])=O)-c1nnc(N)s1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	CCRIS database,Toxnet databases
75965-74-1	7-methoxy-2-nitronaphtho[2,1-b]furan	COc1ccc2c(ccc3oc(cc32)[N+]([O-])=O)c1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	CCRIS database,Toxnet databases: Castelain, Pet. al.; Mutagenic Activity of Dichloroethylamino Derivatives of Nitronaphthofuran and Some Nitrobenzofurans in the Salmonella/Microsome Assay; Mutat. Res. 280(1):9-15, 1992
21638-36-8	Nifurimide	CC1CN(N=Cc2ccc(o2)[N+]([O-])=O)C(=O)N1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240
13551-87-6	misonidazole	COCC(O)Cn1ccnc1[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240; CCRIS database,Toxnet databases: Brusick,Dj, et al; Mutat. Res. 76:169-190, 1980; Chessin, H, et al; Radiat. Res. 75:424-431, 1978
58139-48-3	4-morpholino-2-(5-nitro-2-thienyl)quinazoline	[O-][N+](=O)c1ccc(s1)-c1nc2ccccc2c(n1)N1CCOCC1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240
23256-30-6	Nifurtimox	CC1CS(=O)(=O)CCN1N=Cc1ccc(o1)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	CCRIS database,Toxnet databases: Ferreira, Rcc And Ferreira ,Lcs; Mutagenicity Of Nifurtimox And Benznidazole In The Salmonella/Microsome Assay; Braz. J. Med. Biol. Res. 19(1):19-25, 1986
36133-88-7	n-{[3-(5-nitro-2-furyl)-1,2,4-oxadiazole-5-yl]-methyl}acetamide	CC(=O)NCc1nc(no1)-c1ccc(o1)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240
2578-75-8	n-(5-(5-nitro-2-furanyl)-1,3,4-thiadiazol-2-yl)acetamide	CC(=O)Nc1nnc(s1)-c1ccc(o1)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240
531-82-8	n-(4-(5-nitro-2-furyl)-2-thiazolyl)acetamide	CC(=O)Nc1nc(cs1)-c1ccc(o1)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240; CCRIS database,Toxnet databases
51325-35-0	n,n'-[6-(5-nitro-2-furyl)-s-triazine-2,4-diyl]bisacetamide	CC(=O)Nc1nc(NC(C)=O)nc(n1)-c1ccc(o1)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240
19387-91-8	tinidazole	CCS(=O)(=O)CCn1c(C)ncc1[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	CCRIS database,Toxnet databases: Gupta, Rl., Vats, V. And Juneja, Tr.; Activation Of Tinidazole, An Antiprotozoal Drug To A Mutagen By Mammalian Liver S9; Mutat. Res. 370(3-4):195-201, 1996
67-20-9	Nitrofurantoin	[O-][N+](=O)c1ccc(C=NN2CC(=O)NC2=O)o1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Mccann, J., Choi, E., Yamasaki, E. And Ames, Bn.; Detection Of Carcinogens As Mutagens In The Salmonella/Microsome Test: Assay Of 300 Chemicals; Proc. Natl. Acad. Sci. Usa 72(12):5135-5139, 1975; U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240
59-87-0	Nitrofurazone	NC(=O)NN=Cc1ccc(o1)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240
*10006-72-0	N2-(3-cyano-5-nitro-2-thienyl)-N1,N1-dimethylformamidine	CN(C)\C=N\c1sc(cc1C#N)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html. Divizion of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html; Last update; June 2019
*10008-52-4	5'-[N-(2-cyanoethyl)-N-ethylamino]-4'-methoxy-2'-(5-nitro-2,1-benzisothiazole-3-ylazo)acetoanilide	CCN(CCC#N)c1cc(NC(C)=O)c(cc1OC)\N=N\c1snc2ccc(cc12)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html. Divizion of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html; Last update; June 2019
105076-77-5	5'-[bis(2-methoxyethyl)amino]-2'-(5-nitro-2,1-benzisothiazol-3-ylazo)acetanilide	COCCN(CCOC)c1ccc(N=Nc2snc3ccc(cc23)[N+]([O-])=O)c(NC(C)=O)c1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html. Divizion of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html; Last update; June 2019
118430-73-2	5-tert-butyl-2-methylpyrazol-3-amine	Cn1nc(cc1N)C(C)(C)C	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html. Divizion of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html; Last update; June 2019
122063-39-2	acetic acid 4-[ethyl[4-(3-acetyl-5-nitro-2-thienylazo)-3-methylphenyl]amino]butyl ester	CCN(CCCCOC(C)=O)c1ccc(\N=N\c2sc(cc2C(C)=O)[N+]([O-])=O)c(C)c1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html. Divizion of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html; Last update; June 2019
167940-11-6	2'-(3-acetyl-5-nitro-2-thienylazo)-5'-diethylaminoacetoanilide	CCN(CC)c1ccc(\N=N\c2sc(cc2C(C)=O)[N+]([O-])=O)c(NC(C)=O)c1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html. Divizion of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html; Last update; June 2019
19182-81-1	1,4-dinitroimidazole	[O-][N+](=O)c1cn(cn1)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html. Divizion of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html; Last update; June 2019
29097-01-6	5-amino-1-phenyl-1H-pyrazole-4-carboxylic acid methyl ester	COC(=O)c1cnn(-c2ccccc2)c1N	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html. Divizion of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html; Last update; June 2019
3460-18-2	2,5-dibromonitrobenzene	[O-][N+](=O)c1cc(Br)ccc1Br	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html. Divizion of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html; Last update; June 2019
5153-70-8	1-chloro-4-(2-nitroethenyl)benzene	[O-][N+](=O)\C=C\c1ccc(Cl)cc1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html. Divizion of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html; Last update; June 2019
56387-09-8	2-amino-5-nitro-3-thiophenecarbonitrile	Nc1sc(cc1C#N)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html. Divizion of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html; Last update; June 2019
57531-37-0	2-chloro-4-nitroimidazole	[O-][N+](=O)c1cnc(Cl)[nH]1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html. Divizion of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html; Last update; June 2019
4/7/6061	1,1-dichloro-2-nitroethene	[O-][N+](=O)C=C(Cl)Cl	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html. Divizion of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html; Last update; June 2019
70693-64-0	N,N-diethyl-3-methyl-4-[(5-nitro-1,3-thiazol-2-yl)diazenyl]aniline	CCN(CC)c1ccc(\N=N\c2ncc(s2)[N+]([O-])=O)c(C)c1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html. Divizion of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html; Last update; June 2019
76209-05-7	bis(4-bromo-2-nitrophenyl) disulfide	[O-][N+](=O)c1cc(Br)ccc1SSc1ccc(Br)cc1[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html. Divizion of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html; Last update; June 2019