CAS	Chem.name	Chem.SMILES	#Observed Mutagenicity	Bioassay - 	Reference(s) -
508-59-8	Parthenin	CC{P-}1CCC{P+}2C{P+}(C{P+}3(C)C(=O)C=CC{P+}13O)OC(=O)C2=C	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Ramos A., Parthenin, a sesquiterpene lactone of Parthenium hysterophorus L. is a high toxicity clastogen. Mutation Research, v.514, pp.19-27, (2002)
3068-88-0	beta-Butyrolactone	CC1CC(=O)O1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
1955-45-9	Pivalolactone	CC1(C)COC1=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	P&G Inventory; Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
57-57-8	beta-Propiolactone	O=C1CCO1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	P&G Inventory; U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240
57074-49-4	Diethylhymenovin	CCOC1CC2C(C)CC3C(CC2(C)C(OCC)O1)C(=C)C(=O)O3	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240; Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
57074-51-8	Hymenovin	CC1CC2C(CC3(C)C1CC(O)OC3O)C(=C)C(=O)O2	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240
1748-81-8	Carabrone	CC(=O)CCC1C2CC3C(CC12C)OC(=O)C3=C	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Stuppner, H., Stuppner, H. and Rodriguez, E.; A novel enol-pseudoguaianolide from psilostrophe cooperi; Phytochemistry 27(8):2681-2684, 1988
57377-32-9	Hymenoxone	CC{P+}1CC{P+}2C{P+}(CC{P-}3(C)C{P-}1CC{P+}(O)OC{P-}3O)C(=C)C(=O)O2	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Jones DH,  Toxicol Lett., 9, pp. 395-401. (1981)
*10013-68-9	methacrylic acid 4,4-dimethyl-10-oxo-3,5,7,11-tetraoxatricyclo[6.3.0.02,6]undecan-9-yl	CC(=C)C(=O)OC1C2C(C3C(O2)OC(C)(C)O3)OC1=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html. Divizion of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html; Last update; June 2019