CAS	Chem.name	Chem.SMILES	#Observed Mutagenicity	Bioassay - 	Reference(s) -
53-96-3	2-acetylaminofluorene	CC(=O)Nc1ccc2c(Cc3ccccc3-2)c1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240; P&G Inventory
134-32-7	1-Naphthylamine	Nc1cccc2ccccc12	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240; P&G Inventory
610-49-1	1-Anthracenamine	Nc1cccc2cc3ccccc3cc12	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240; P&G Inventory
881-03-8	1-Nitro-2-Methylnaphthalene	Cc1ccc2ccccc2c1[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	P&G Inventory
28322-02-3	4-Acetylaminofluorene	CC(=O)Nc1cccc2Cc3ccccc3-c21	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	P&G Inventory; U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240
67219-70-9	1-Butyl-2-Aminonaphthalene; 1-Butyl-naphthalen-2-ylamine	CCCCc1c(N)ccc2ccccc12	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	P&G Inventory
2508-23-8	N-Hydroxy-N-2-naphthalenylacetamide	CC(=O)N(O)c1ccc2ccccc2c1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Wang, C.Y., Linsmaier - Bednar, E. M., Lee, M. S. and King, C. M.; Mutagenicities of N-Acyl-N-Arylhydroxylamines for Salmonella; Chem-Biol. Interact. 67(3-4):215-223, 1988
553-30-0	Proflavine sulfate	OS(O)(=O)=O.Nc1ccc2cc3ccc(N)cc3nc2c1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	P&G Inventory
6109-97-3	Carbazole, 3-amino-9-ethyl-, hydrochloride	[Cl-].CCn1c2ccccc2c2cc([NH2+])ccc21	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	P&G Inventory
551-06-4	1-Naphthylisothiocyanate	S=C=Nc1cccc2ccccc21	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	P&G Inventory; U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240
607-59-0	Aniline, N,N-dimethyl-p-(1-naphthylazo)-	CN(C)c1ccc(cc1)N=Nc1cccc2ccccc21	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Short-Term Test Program Sponsored By The Division Of Cancer Biology, National Cancer Institute, Ms. Ellen Zaika, Assistant Project Officer , p. Y82
91-59-8	2-naphthylamine	Nc1ccc2ccccc2c1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	CCRIS database,Toxnet databases: Jordan, Vc., Lababidi, Mk. And Langan-Fahey, S.; Suppression Of Mouse Mammary Tumorigenesis By Long-Term Tamoxifen Therapy; J. Natl. Cancer Inst. 83:492-496, 1991
8048-52-0	Acriflavine	[Cl-].Nc1ccc2cc3ccc(N)cc3nc2c1.C[n+]1c2cc(N)ccc2cc2ccc(N)cc21	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	CCRIS database, Toxnet database: Brown, Jp. and Brown, Rj.; Mutagenesis by 9,10-Anthraquinone Derivatives and Related Compounds in Salmonella Typhimurium; Mutat. Res. 40:203-224, 1976
607-57-8	2-Nitro-9H-fluorene	[O-][N+](=O)c1ccc2c(Cc3ccccc3-2)c1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240
606-37-1	1,3-Dinitronaphthalene	[O-][N+](=O)c1cc2ccccc2c(c1)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
2243-61-0	1,4-Naphthylenediamine	Nc1ccc(N)c2ccccc12	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	P&G Inventory; Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
2243-62-1	1,5-Naphthalenediamine	Nc1cccc2c(N)cccc12	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	P&G Inventory; Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
53-95-2	N-Hydroxy-2-acetamidofluorene	CC(=O)N(O)c1ccc2c(Cc3ccccc3-2)c1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	P&G Inventory; U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240
8/8/6610	Naphthalene, 2-nitroso-	O=Nc1ccc2ccccc2c1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	P&G Inventory; U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240
108100-28-3	9H-Fluorene, 2-methyl-7-nitro-	Cc1ccc2c(Cc3cc(ccc3-2)[N+]([O-])=O)c1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	P&G Inventory; Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
188107-70-2	9-Methyl-2-nitrocarbazole	Cn1c2ccccc2c2ccc(cc21)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	P&G Inventory; Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
613-47-8	Hydroxylamine, N-2-naphthyl-	ONc1ccc2ccccc2c1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	P&G Inventory; U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240
389104-57-8	1-Isopropyl-9H-fluoren-2-ylamine	CC(C)c1c(N)ccc2-c3ccccc3Cc21	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
602-38-0	1,8-Dinitronaphthalene	[O-][N+](=O)c1cccc2cccc(c21)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	P&G Inventory; Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
602-60-8	9-Nitroanthracene	[O-][N+](=O)c1c2ccccc2cc2ccccc21	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	P&G Inventory; Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
602-87-9	5-Nitroacenaphthene	[O-][N+](=O)c1ccc2CCc3cccc1c32	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	P&G Inventory; U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240
605-71-0	1,5-Dinitronaphthalene	[O-][N+](=O)c1cccc2c(cccc12)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	P&G Inventory; Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
86-57-7	1-Nitronaphthalene	[O-][N+](=O)c1cccc2ccccc21	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	P&G Inventory; Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
42397-64-8	1,6-Dinitropyrene	[O-][N+](=O)c1ccc2ccc3c(ccc4ccc1c2c43)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	P&G Inventory; Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
42397-65-9	1,8-Dinitropyrene	[O-][N+](=O)c1ccc2ccc3ccc(c4ccc1c2c34)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	P&G Inventory; Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
128714-75-0	1,6-Dinitrobenzo(a)pyrene	[O-][N+](=O)c1ccc2ccc3c(c4ccccc4c4ccc1c2c43)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
3025-77-2	1-((4-Nitrophenyl)azo)-2-naphthalenamine	Nc1ccc2ccccc2c1N=Nc1ccc(cc1)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	P&G Inventory; Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
188107-72-4	1,4,6-Trimethyl-3-nitrocarbazole	Cc1ccc2[nH]c3c(C)cc(c(C)c3c2c1)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
72917-35-2	1,4-Dimethyl-6-hydroxy-3-nitrocarbazole	Cc1cc(c(C)c2c3cc(O)ccc3[nH]c12)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	P&G Inventory; Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
129117-54-0	1,4-Dimethyl-6-methoxy-3-aminocarbazole	COc1ccc2[nH]c3c(C)cc(N)c(C)c3c2c1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
6344-66-7	Fluoren-3-amine	Nc1ccc2Cc3ccccc3-c2c1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Later, Dw., Pelroy, Ra., Stewart, Dl., Mcfall, T., Booth, Gm., Lee, Ml., Tedjamulia, M. And Castle, Rn.; Microbial Mutagenicity Of Isomeric Two-, Three-, And Four-Ring Amino Polycyclic Aromatic Hydrocarbons; Environ. Mutagen. 6(4):497-515, 1984
53-94-1	Hydroxylamine, N-fluoren-2-yl-	ONc1ccc2c(Cc3ccccc3-2)c1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240
607-30-7	1-Naphthylhydroxylamine	ONc1cccc2ccccc12	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240
95331-48-9	Acetamide, N-hydroxy-N-1-pyrenyl-	CC(=O)N(O)c1ccc2ccc3cccc4ccc1c2c34	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Ball, LM, Kohan, MJ, Claxton, LD and Lewtas, J;Mutagenicity of Derivatives and Metabolites of 1-Nitropyrene: Activation by Rat Liver S9 and Bacterial Enzymes; Mutat. Res. 138(2-3):113-125, 1984
144425-09-2	9-Methoxytariacuripyrone	COc1ccc2cc(c3C=CC(=O)Oc3c2c1)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Schimmer, O. and Drewello,U; 9-Methoxytariacuripyrone, a Naturally Occurring Nitro-Aromatic Compound with Strong Mutagenicity in Salmonella Typhimurium; Mutagenesis 9(6):547-551, 1994
*6-01-8	ICR 415	CCN(CCCl)CCOCCNc1c2ccc(Cl)cc2nc2ccc(OC)nc12	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	DeMarini D.M.,et.al, Relationships between structures and mutagenic potencies of 16 heterocyclic nitrogen mustards (ICR compounds) in Salmonella typhimurium Mut.Research, 136 (1984) 185-199
62450-06-0	Trp-P-1	Cc1nc(N)c(C)c2[nH]c3ccccc3c12	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Hayashi, K., Matsukubo, K. Nagashima, T., Ishikawa, T., Hashida, C. And Shimizu, H.; Fluctuation Test In Rat Bladder S9-Mediated Mutagenesis Of Several Chemicals; Nippon Eiseigaku Zasshi 43(4):934-9, 1988
90-45-9	9-Aminoacridine	Nc1c2ccccc2nc2ccccc12	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240; Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
153-78-6	2-Aminofluorene	Nc1ccc2c(Cc3ccccc3-2)c1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	U.S. Environmental Protection Agency, Mutation Research, 168 (1986) 69-240; O'donovan, Mr.; The Comparative Responses Of Salmonella Typhimurium T?1537 And T?97a To A Range Of Reference Mutagens And Novel Compounds; Mutagenesis 5(3):267-274, 1990
613-13-8	2-Anthracenamine	Nc1ccc2cc3ccccc3cc2c1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Diehl, M. And Fort, F.; Spiral Salmonella Assay: Validation Against The Standard Pour-Plate Assay; Environ. Mol. Mutagen. 27(3):227-236, 1996
1606-67-3	1-Aminopyrene	Nc1ccc2ccc3cccc4ccc1c2c34	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Ball, LM, Kohan, MJ, Claxton, LD and Lewtas, J;Mutagenicity of Derivatives and Metabolites of 1-Nitropyrene: Activation by Rat Liver S9 and Bacterial Enzymes; Mutat. Res. 138(2-3):113-125, 1984
389104-56-7	Fluorene, 1-ethyl-2-amino-	CCc1c(N)ccc2c1Cc1ccccc1-2	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Glende, C Schmitt, et. al.; Transformation Of Mutagenic Aromatic Amines Into Non-Mutagenic Species By Alkyl Substituents. Part I. Alkylation Ortho To The Amino Function. Mutat. Res. 498(1-2):19-37, 2001
89459-43-8	N-((2-Dimethylamino)ethyl)-9-aminoacridine-4-carboxamide	CN(C)CCNC(=O)c1cccc2c(N)c3ccccc3nc12	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Denny, Wa, et. al; Structure- Activity Relationships For The Mutagenic Activity Of Tricyclic Intercalating Agents In Salmonella Typhimurium; Mutat. Res. 232(2):233-241, 1990; Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
56-57-5	4-Nitroquinoline-N-oxide	[O-][N+](=O)c1cc[n+]([O-])c2ccccc12	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240
4637-56-3	4-Hydroxyaminoquinoline-1-oxide	ONc1cc[n+]([O-])c2ccccc12	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240; Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
2508-20-5	2-Nitrosofluorene	O=Nc1ccc2c(Cc3ccccc3-2)c1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240; Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
389104-58-9	Fluorene, 1-butyl-2-amino-	CCCCc1c(N)ccc2c1Cc1ccccc1-2	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Glende, C Schmitt, H Erdinger, L Engelhardt, G And Boche, G; Transformation Of Mutagenic Aromatic Amines Into Non-Mutagenic Species By Alkyl Substituents. Part I. Alkylation Ortho To The Amino Function. Mutat. Res. 498(1-2):19-37, 2001
313-67-7	Aristolochic acid	COc1cccc2c1cc(c1c(cc3OCOc3c21)C(O)=O)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	CCRIS database,Toxnet databases
525-64-4	2,7-diamino-fluoren	Nc1ccc2c(Cc3cc(N)ccc3-2)c1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	CCRIS database,Toxnet databases: Mccann, J, Choi, E, Yamasaki, E And Ames, Bn; Detection Of Carcinogens As Mutagens In The Salmonella/Microsome Test: Assay Of 300 Chemicals; Proc. Natl. Acad. Sci. Usa 72(12):5135-5139, 1975
33389-36-5	Quinazoline, 4-(2-hydroxyethylamino)-2-(5-nitro-2-thienyl)-	OCCNc1nc(nc2ccccc12)-c1ccc(s1)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	CCRIS database,Toxnet databases: Mccann, J, Choi, E, Yamasaki, E And Ames, Bn; Detection Of Carcinogens As Mutagens In The Salmonella/Microsome Test: Assay Of 300 Chemicals; PROC. NATL. ACAD. SCI. USA 72(12):5135-5139, 1975
2/8/7496	6-nitrochrysene	[O-][N+](=O)c1cc2c3ccccc3ccc2c2ccccc12	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	CCRIS database,Toxnet databases: El-Bayoumy, K, et al; Mutagenicity, Metabolism And DNA Adduct Formation Of 6-Nitrochrysene In Salmonella Typhimurium; Mutagenesis 4(3):235-240, 1989
581-89-5	2-nitronaphthalene;2nitronaphthalene	[O-][N+](=O)c1ccc2ccccc2c1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	CCRIS database,Toxnet databases: Mccann, J, Choi, E, Yamasaki, E And Ames, Bn; Detection Of Carcinogens As Mutagens In The Salmonella/Microsome Test: Assay Of 300 Chemicals; Proc. Natl. Acad. Sci. USA 72(12):5135-5139, 1975
5522-43-0	1-nitropyrene;pyrene, 1-nitro-	[O-][N+](=O)c1ccc2ccc3cccc4ccc1c2c34	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	CCRIS database,Toxnet databases
607-35-2	8-nitroquinoline;quinoline, 8-nitro-	[O-][N+](=O)c1cccc2cccnc21	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240
151285-25-5	2-[3-(2,6-dichloro-4-nitrophenylazo)-9H-carbazole-9-yl]ethanol	OCCn1c2ccccc2c2cc(ccc21)\N=N\c1c(Cl)cc(cc1Cl)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html. Divizion of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html; Last update; June 2019