CAS	Chem.name	Chem.SMILES	#Observed Mutagenicity	Bioassay - 	Reference(s) -
464-10-8	Bromopicrin	[O-][N+](=O)C(Br)(Br)Br	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	P&G Inventory
76-06-2	Chloropicrin	[O-][N+](=O)C(Cl)(Cl)Cl	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kawai, A., Goto, S., Matsumoto, Y. and Matsushita ,H.; Sangyo Igaku 29(1):34-55, 1987; 
75-35-4	1,1-Dichloroethylene	ClC(Cl)=C	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Strobel, K. and Grummt, T.; Aliphatic and Aromatic Halocarbons as Potential Mutagens an Drinking Water. III. Halogenated Ethanes and Ethenes; Toxicol. Environ. Chem. 15(1-2):101-128, 1987
79-27-6	1,1,2,2-Tetrabromoethane	BrC(Br)C(Br)Br	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Strubel, K., T. Grummt, Aliphatic and Aromatic Halocarbons as Potential Mutagens in Drinking Water. III. Halogenated Ethanes and Ethenes, Toxicol. Environ. Chem. 15(1-2) (1987), 101 – 128
302-17-0	Chloral hydrate	OC(O)C(Cl)(Cl)Cl	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	P&G Inventory; U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240
133-06-2	Captan	ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	P&G Inventory; U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240
3018-12-0	Dichloroacetonitrile	ClC(Cl)C#N	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	P&G Inventory; U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240
52-68-6	Trichlorfon	COP(=O)(OC)C(O)C(Cl)(Cl)Cl	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	P&G Inventory; Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
75-25-2	Tribromometan	BrC(Br)Br	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	P&G Inventory; Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
75-47-8	Triiodomethane	IC(I)I	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	P&G Inventory; Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
79-36-7	acetyl chloride, dichloro-	ClC(Cl)C(Cl)=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	P&G Inventory; Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
98-07-7	Benzotrichloride	ClC(Cl)(Cl)c1ccccc1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	P&G Inventory; Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
98-87-3	alpha,alpha-Dichlorotoluene	ClC(Cl)c1ccccc1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	P&G Inventory; Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
3252-43-5	Dibromoacetonitrile	BrC(Br)C#N	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	P&G Inventory; Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
75-87-6	Trichloroacetaldehyde	ClC(Cl)(Cl)C=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Waskell, L.; A Study Of The Mutagenicity Of Anesthetics And Their Metabolites; Mutat. Res. 57:141-153, 1978
75-27-4	Bromodichloromethane	ClC(Cl)Br	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	U.S. Environmental Protection Agency, Mutation Research, 168 (1986) 69-240
124-48-1	Chlorodibromomethane	ClC(Br)Br	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Varma, Mm, Ampy, Fr, Verma, K And Talbot, Ww; In Vitro Mutagenicity Of Water Contaminants In Complex Mixtures; J. Appl. Toxicol. 8(4):243-248, 1988
31555-54-1	3,4-dichloro-5-dichloromethylene-2-furanone	ClC(Cl)=C1OC(=O)C(Cl)=C1Cl	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Smeds, A, Franzen, R And Kronberg, L; Occurrence Of Some Chlorinated Enol Lactones And Cyclopentene-1,3-Diones In Chlorine-Treated Waters; Environ. Sci. Technol. 29(9):1839-1844, 1995; Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
112654-68-9	3-chloro-5-dichloromethylene-2-furanone	ClC(Cl)=C1OC(=O)C(Cl)=C1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Smeds, A, Franzen, R And Kronberg, L; Occurrence Of Some Chlorinated Enol Lactones And Cyclopentene-1,3-Diones In Chlorine-Treated Waters; Environ. Sci. Technol. 29(9):1839-1844, 1995
75-09-2	Dichloro-methane; methylene chloride	ClCCl	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	U.S. Environmental Protection Agency, Mutation Research, 168 (1986) 69-240
545-06-2	Trichloroacetonitrile	ClC(Cl)(Cl)C#N	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Le Curieux, F, Giller, S, Gauthier, L, Erb, F And Marzin, D; Study Of The Genotoxic Activity Of Six Halogenated Acetonitriles, Using The Sos Chromotest, The Ames-Fluctuation Test And The Newt Micronucleus Test; Mutat. Res. 341(4): 289-302, 1994; Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
79-00-5	1,1,2-Trichloroethane	ClCC(Cl)Cl	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Strobel, K And Grummt, T; Aliphatic And Aromatic Halocarbons As Potential Mutagens In Drinking Water. Iii. Halogenated Ethanes And Ethenes; Toxicol. Environ. Chem. 15(1-2):101-128, 1987
630-20-6	1,1,1,2-Tetrachloroethane	ClCC(Cl)(Cl)Cl	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Strobel, K And Grummt, T; Aliphatic And Aromatic Halocarbons As Potential Mutagens In Drinking Water. Iii. Halogenated Ethanes And Ethenes; Toxicol. Environ. Chem. 15(1-2):101-128, 1987
67-66-3	Chloroform	ClC(Cl)Cl	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Varma, Mm, Ampy, Fr, Verma, K And Talbot, Ww; In Vitro Mutagenicity Of Water Contaminants In Complex Mixtures; J. Appl. Toxicol. 8(4):243-248, 1988
79-01-6	Trichloroethylene	ClC=C(Cl)Cl	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Strobel, K And Grummt, T; Aliphatic And Aromatic Halocarbons As Potential Mutagens In Drinking Water. III. Halogenated Ethanes And Ethenes; Toxicol. Environ. Chem. 15(1-2):101-128, 1987
5589-96-8	bromochloroacetic acid	OC(=O)C(Cl)Br	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	CCRIS database,Toxnet databases
6/1/2425	Captafol	ClC(Cl)C(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	CCRIS database,Toxnet databases: Barrueco, C. and De La Pena, E.; Mutagenic Evaluation of the Pesticides Captan, Folpet, Captafol, Dichlofluanid and Related Compounds with the Mutants TA 102 and TA 104 of Salmonella Typhimurium; Mutagenesis 3(6):467-480, 1988
75-45-6	chlorodifluoromethane	FC(F)Cl	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Anders, M. W., Metabolism and Toxicity of Hydrochlorofluorocarbons: Current Knowledge and Needs for the Future, Environ. Health Persp. 96 (1991), 185 – 191
631-64-1	dibromoacetic acid	OC(=O)C(Br)Br	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	CCRIS database,Toxnet databases: Saito, H, Isoda, S, Kato, M And Nagaoka, N; Mutagenic Activity Of Indoor Swimming Pool Water; Kankyo Henigen Kenkyu 17(2):169-177, 1995
79-43-6	Dichloracetic acid; Acetic acid, 2,2-dichloro-	OC(=O)C(Cl)Cl	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	CCRIS database,Toxnet databases: Demarini, Dm., Perry, E. And Shelton, Ml.; Dichloroacetic Acid And Related Compounds: Induction Of Prophage In E. Coli And Mutagenicity And Mutation Spectra In Salmonella TA100; Mutagenesis 9(5):429-437, 1994
2314-97-8	Iodotrifluoromethane	FC(F)(F)I	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	CCRIS database,Toxnet databases: Dodd, De, Ledbetter, Ad and Mitchell, AD; Genotoxicity Testing Of The Halon Replacement Candidates Trifluoroiodomethane (CF3I) AND 1,1,1,2,3,3,3-Heptafluoropropane (HFC-227EA) Using The Salmonella Typhimurium And L5178Y Mouse Lymphoma Mutation Assays And The Mouse Micronucleus Test; Inhalation Toxicol. 9(2):111-131, 1997
133-07-3	Folpet; N-(trichloromethylthio)phthalimide	ClC(Cl)(Cl)SN1C(=O)c2ccccc2C1=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240
3083-23-6	1,2-epoxy-3,3,3-trichloropropane	ClC(Cl)(Cl)C1CO1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	CCRIS database,Toxnet databases: Einisto, P, Hooberman, Bh And Sinsheimer, Je; Base-Pair Mutations Caused By Six Aliphatic Epoxides In Salmonella Typhimurium Ta100, Ta104, Ta4001, And Ta4006; Environ. Mol. Mutagen. 21(3):253-257, 1993
71-55-6	methylchloroform	CC(Cl)(Cl)Cl	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	CCRIS database,Toxnet databases: Strubel, K., T. Grummt, Aliphatic and Aromatic Halocarbons as Potential Mutagens in Drinking Water. III. Halogenated Ethanes and Ethenes, Toxicol. Environ. Chem. 15(1-2) (1987), 101 – 128
8001-35-2	toxaphene	CC1(C)C(=C)C2(Cl)C(Cl)(Cl)C(Cl)(Cl)C1(Cl)C2(Cl)Cl	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Hosey, K. M. Quinn, J. J. Roche, M. Fogarty, C. A. Brougham, Screening for Genotoxicity and Oestrogenicity of Endocrine Disrupting Chemicals In Vitro, J. Environ. Protection 3 (21012), 902 – 914
*10007-29-9	2-[2-methoxy-4-[3-[2-(trichloroacetyl)hydrazino]-3-oxo-1-propenyl]phenoxy]acetic acid methyl ester	COC(=O)COc1ccc(\C=C\C(=O)NNC(=O)C(Cl)(Cl)Cl)cc1OC	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html.
*10010-69-5	2-(6-tert-butyl-7,7-dichloro-7H-pyrazolo[5,1-c][1,2,4]triazole-3-yl)-2-methylpropane-1-ol	CC(C)(C)C1=Nn2c(nnc2C1(Cl)Cl)C(C)(C)CO	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html.
*10018-08-9	2-(2-chloro-5-chloroacetyl-4-fluorophenoxy)-N-methylacetamide	CNC(=O)COc1ccc(F)c(c1)C(=O)C(Cl)Cl	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html.
1768-31-6	1,1,1,3,3-pentachloroacetone	ClC(Cl)C(=O)C(Cl)(Cl)Cl	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html.
18964-69-7	4,5-dichloro-2-(trichloromethyl)toluene	Cc1cc(Cl)c(Cl)cc1C(Cl)(Cl)Cl	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html.
23063-36-7	1-(dichloromethyl)-4-methylbenzene	Cc1ccc(cc1)C(Cl)Cl	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html.
30293-58-4	1-(chloromethyl)-2-(dichloromethyl)benzene	ClCc1ccccc1C(Cl)Cl	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html.
380-44-9	3-(2-chloro-1,1,2-trifluoroethoxy)prop-1-ene	FC(Cl)C(F)(F)OCC=C	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html.
401-55-8	ethyl 2-bromo-2-fluoroacetate	CCOC(=O)C(F)Br	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html.
4124-31-6	(2,2,2-trichloroacetyl) 2,2,2-trichloroacetate	ClC(Cl)(Cl)C(=O)OC(=O)C(Cl)(Cl)Cl	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html.
64326-81-4	1,1,1-trichloro-2-nitroethane	[O-][N+](=O)CC(Cl)(Cl)Cl	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html.
96405-52-6	2-trichloromethyl-5-(4-hydroxystyryl)-1,3,4-oxadiazole	Oc1ccc(\C=C\c2nnc(o2)C(Cl)(Cl)Cl)cc1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html.
99938-06-4	2,6-dichloro-3-(trichloromethyl)toluene	Cc1c(Cl)ccc(c1Cl)C(Cl)(Cl)Cl	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html.
3776-30-5	2,2,6,6-tetrachlorocyclohexanone	O=C1C(Cl)(Cl)CCCC1(Cl)Cl	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html.