CAS	Chem.name	Chem.SMILES	#Observed Mutagenicity	Bioassay - 	Reference(s) -
77439-76-0	3-chloro-4-(dichloromethyl)-5-hydroxy-2(5h)-furanone	OC1C(C(Cl)Cl)=C(Cl)C(=O)O1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Meier, Jr, Blazak, Wf And Knohl, Rb; Mutagenic And Clastogenic Properties Of 3-Chloro-4-(Dichloromethyl)-5-Hydroxy-2(5h)-Furanone: A Potent Bacterial Mutagen In Drinking Water; Environ. Mol. Mutagen. 10:411-424, 1987; Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
766-40-5	3,4-dichloro-5-hydroxy-2(5h)-furanone	OC1C(Cl)=C(Cl)C(=O)O1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Lalonde, Rt And Leo, Hr; Interactive Chlorine-By-Bromine And Hydrogen-By-Hydroxyl Group Replacement Effects In 2(5h)-Furanone Mutagenicity; Chem. Res. Toxicol. 7(6):779-783, 1994; Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
112309-61-2	3-chloro-4-methyl-5-hydroxy-2(5h)-furanone	CC1C(O)OC(=O)C=1Cl	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Lalonde, Rt And Leo, Hr; Interactive Chlorine-By-Bromine And Hydrogen-By-Hydroxyl Group Replacement Effects In 2(5h)-Furanone Mutagenicity; Chem. Res. Toxicol. 7(6):779-783, 1994
31555-54-1	3,4-dichloro-5-dichloromethylene-2-furanone	O=C1C(Cl)=C(Cl)C(=C(Cl)Cl)O1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Smeds, A, Franzen, R And Kronberg, L; Occurrence Of Some Chlorinated Enol Lactones And Cyclopentene-1,3-Diones In Chlorine-Treated Waters; Environ. Sci. Technol. 29(9):1839-1844, 1995; Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
97055-38-4	3-chloro-4-(dichloromethyl)-5-methoxy-2(5h)-furanone	COC1C(C(Cl)Cl)=C(Cl)C(=O)O1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Ishiguro, Y, Lalonde, Rt, Dence, Cw And Santodonato ,J; Mutagenicity Of Chlorine-Substituted Furanones And Their Inactivation By Reaction With Nucleophiles;Environ. Toxicol. Chem; Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
112654-68-9	3-chloro-5-dichloromethylene-2-furanone	O=C1C(Cl)=CC(=C(Cl)Cl)O1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Smeds, A, Franzen, R And Kronberg, L; Occurrence Of Some Chlorinated Enol Lactones And Cyclopentene-1,3-Diones In Chlorine-Treated Waters; Environ. Sci. Technol. 29(9):1839-1844, 1995
122551-89-7	3-chloro-4-(dichloromethyl)-2(5h)-furanone	O=C1C(Cl)=C(C(Cl)Cl)CO1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Lalonde, Rt And Leo, Hr; Interactive Chlorine-By-Bromine And Hydrogen-By-Hydroxyl Group Replacement Effects In 2(5h)-Furanone Mutagenicity; Chem. Res. Toxicol. 7(6):779-783, 1994
125974-01-8	3-chloro-4-(chloromethyl)-2(5h)-furanone	O=C1C(Cl)=C(CCl)CO1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Lalonde, Rt And Leo, Hr; Interactive Chlorine-By-Bromine And Hydrogen-By-Hydroxyl Group Replacement Effects In 2(5h)-Furanone Mutagenicity; Chem. Res. Toxicol. 7(6):779-783, 1994
125974-08-5	3-chloro-4-(chloromethyl)-5-hydroxy-2(5h)-furanone	OC1C(CCl)=C(Cl)C(=O)O1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Lalonde, Rt And Leo, Hr; Interactive Chlorine-By-Bromine And Hydrogen-By-Hydroxyl Group Replacement Effects In 2(5h)-Furanone Mutagenicity; Chem. Res. Toxicol. 7(6):779-783, 1994
132059-51-9	3-chloro-4-(bromochloromethyl)-5-hydroxy-2(5h)-furanone	OC1C(C(Cl)Br)=C(Cl)C(=O)O1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Suzuki, N And Matsuo, T; Fractionation And Identification Of Mutagens In Chlorinated Tap Water; J. Fac. Eng. Univ. Tokyo, Ser.B 42(4):307-315, 1994
132059-52-0	3-chloro-4-(dibromomethyl)-5-hydroxy-2(5h)-furanone	OC1C(C(Br)Br)=C(Cl)C(=O)O1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Suzuki, N And Matsuo, T; Fractionation And Identification Of Mutagens In Chlorinated Tap Water; J. Fac. Eng. Univ. Tokyo, Ser.B 42(4):307-315, 1994
132059-53-1	3-bromo-4-(dibromomethyl)-5-hydroxy-2(5h)-furanone	OC1C(C(Br)Br)=C(Br)C(=O)O1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Suzuki, N And Matsuo, T; Fractionation And Identification Of Mutagens In Chlorinated Tap Water; J. Fac. Eng. Univ. Tokyo, Ser.B 42(4):307-315, 1994
149418-41-7	3,4-dibromo-2(5h)-furanone	O=C1C(Br)=C(Br)CO1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Lalonde, Rt And Leo, Hr; Interactive Chlorine-By-Bromine And Hydrogen-By-Hydroxyl Group Replacement Effects In 2(5h)-Furanone Mutagenicity; Chem. Res. Toxicol. 7(6):779-783, 1994
199536-62-4	3-bromo-4-(bromomethyl)-2(5h)-furanone	O=C1C(Br)=C(CBr)CO1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Lalonde, Rt And Leo, Hr; Interactive Chlorine-By-Bromine And Hydrogen-By-Hydroxyl Group Replacement Effects In 2(5h)-Furanone Mutagenicity; Chem. Res. Toxicol. 7(6):779-783, 1994
199536-64-6	3-bromo-4-(bromomethyl)-5-hydroxy-2(5h)-furanone	OC1C(CBr)=C(Br)C(=O)O1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Lalonde, Rt And Leo, Hr; Interactive Chlorine-By-Bromine And Hydrogen-By-Hydroxyl Group Replacement Effects In 2(5h)-Furanone Mutagenicity; Chem. Res. Toxicol. 7(6):779-783, 1994
199536-65-7	3-chloro-4-(bromomethyl)-2(5h)-furanone	O=C1C(Cl)=C(CBr)CO1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Lalonde, Rt And Leo, Hr; Interactive Chlorine-By-Bromine And Hydrogen-By-Hydroxyl Group Replacement Effects In 2(5h)-Furanone Mutagenicity; Chem. Res. Toxicol. 7(6):779-783, 1994
199536-79-3	3-bromo-4-(dibromomethyl)-2(5h)-furanone	O=C1C(Br)=C(C(Br)Br)CO1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Lalonde, Rt And Leo, Hr; Interactive Chlorine-By-Bromine And Hydrogen-By-Hydroxyl Group Replacement Effects In 2(5h)-Furanone Mutagenicity; Chem. Res. Toxicol. 7(6):779-783, 1994
199536-82-8	3-chloro-4-(dibromomethyl)-2(5h)-furanone	O=C1C(Cl)=C(C(Br)Br)CO1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Lalonde, Rt And Leo, Hr; Interactive Chlorine-By-Bromine And Hydrogen-By-Hydroxyl Group Replacement Effects In 2(5h)-Furanone Mutagenicity; Chem. Res. Toxicol. 7(6):779-783, 1994
199536-84-0	3-bromo-4-(chloromethyl)-2(5h)-furanone	O=C1C(Br)=C(CCl)CO1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Lalonde, Rt And Leo, Hr; Interactive Chlorine-By-Bromine And Hydrogen-By-Hydroxyl Group Replacement Effects In 2(5h)-Furanone Mutagenicity; Chem. Res. Toxicol. 7(6):779-783, 1994