CAS	Chem.name	SMILES	#Observed Mutagenicity	Bioassay - 	Reference(s) -
139-94-6	Nithiazide	CCNC(=O)Nc1ncc(s1)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	P&G Inventory; Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
24554-26-5	N-(4-(5-Nitro-2-furyl)-2-thiazolyl)formamide	[O-][N+](=O)c1ccc(o1)-c1csc(NC=O)n1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	P&G Inventory; U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240
3688-53-7	2-(2-Furyl)-3-(5-nitro-2-furyl)acrylamide	NC(=O)C(=Cc1ccc(o1)[N+]([O-])=O)c1ccco1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	P&G Inventory; U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240
443-48-1	Metronidazole	Cc1ncc(n1CCO)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	P&G Inventory; U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240
38514-71-5	anft;2-amino-4-(5-nitro-2-furyl)thiazole	Nc1nc(cs1)-c1ccc(o1)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240; CCRIS database,Toxnet databases
22994-85-0	benznidazole; 1h-imidazole-1-acetamide, 2-nitro-n-(phenylmethy	[O-][N+](=O)c1nccn1CC(=O)NCc1ccccc1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	CCRIS database,Toxnet databases
720-69-4	4,6-diamino-2-(5-nitro-2-furyl)-1,3,5-triazine	Nc1nc(N)nc(n1)-c1ccc(o1)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	CCRIS database,Toxnet databases: Rinkus, Sj And Legator, Ms; Chemical Characterization Of 465 Known Or Suspected Carcinogens And Their Correlation With Mutagenic Activity In The Salmonella Typhimurium System; Cancer Res. 39:3289-3318, 1979
33389-33-2	1,2-dihydro-2-(5-nitro-2-thienyl)quinazoline-4-(3h)-one	[O-][N+](=O)c1ccc(s1)C1NC(=O)c2ccccc2N1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	CCRIS database,Toxnet databases: Mccann, J, Choi, E, Yamasaki, E And Ames, Bn; Detection Of Carcinogens As Mutagens In The Salmonella/Microsome Test: Assay Of 300 Chemicals; PROC. NATL. ACAD. SCI. USA 72(12):5135-5139, 1975
55738-54-0	trans-2-[(dimethylamino)methylimino]-5-[2-(5-nitro-2-furyl)vinyl]-1,3,4-oxadiazo	CN(C)CN=C1NN=C(O1)C=Cc1ccc(o1)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240; NCI; The Salmonella Typhimurium/Mammalian Microsomal Assay: A Report Of The U.S. Environmental Protection Agency Gene-Tox Program; Mutat Res 168:69-240,1986
26049-69-4	2-(2,2-dimethylhydrazino)-4-(5-nitro-2-furyl)thiazole	CN(C)Nc1nc(cs1)-c1ccc(o1)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240; CCRIS database,Toxnet databases: Rinkus, Sj And Legator, Ms; Chemical Characterization Of 465 Known Or Suspected Carcinogens And Their Correlation With Mutagenic Activity In The Salmonella Typhimurium System; Cancer Res. 39:3289-3318, 1979;
551-92-8	1,2-dimethyl-5-nitroimidazole	Cc1ncc(n1C)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	CCRIS database,Toxnet databases: Vanelle, P, De Meo, Mp, Maldonado, J, Nouguier, R, Crozet, Mp, Laget, M And Dumenil, G; Genotoxicity In Oxazolidine Derivatives: Influence Of The Nitro Group; Eur. J. Med. Chem. 25(3):241-250, 1990
3570-75-0	nifurthiazole;formic acid 2-[4-(5-nitro-2-furyl)-2-thiazolyl]hydrazide	[O-][N+](=O)c1ccc(o1)-c1csc(NNC=O)n1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240
33389-36-5	Quinazoline, 4-(2-hydroxyethylamino)-2-(5-nitro-2-thienyl)-	OCCNc1nc(nc2ccccc12)-c1ccc(s1)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	CCRIS database,Toxnet databases: Mccann, J, Choi, E, Yamasaki, E And Ames, Bn; Detection Of Carcinogens As Mutagens In The Salmonella/Microsome Test: Assay Of 300 Chemicals; PROC. NATL. ACAD. SCI. USA 72(12):5135-5139, 1975
5036-03-3	1-(2-hydroxyethyl)-3-[(5-nitrofurfurylidene)amino]-2-imidazolidinone;nifurdazil	OCCN1CCN(N=Cc2ccc(o2)[N+]([O-])=O)C1=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240
19622-55-0	cl 64855	Cn1c(ncc1[N+]([O-])=O)-c1nnc(N)s1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	CCRIS database,Toxnet databases
21638-36-8	Nifurimide	CC1CN(N=Cc2ccc(o2)[N+]([O-])=O)C(=O)N1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240
13551-87-6	misonidazole	COCC(O)Cn1ccnc1[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240; CCRIS database,Toxnet databases: Brusick,Dj, et al; Mutat. Res. 76:169-190, 1980; Chessin, H, et al; Radiat. Res. 75:424-431, 1978
58139-48-3	4-morpholino-2-(5-nitro-2-thienyl)quinazoline	[O-][N+](=O)c1ccc(s1)-c1nc2ccccc2c(n1)N1CCOCC1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240
23256-30-6	Nifurtimox	CC1CS(=O)(=O)CCN1N=Cc1ccc(o1)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	CCRIS database,Toxnet databases: Ferreira, Rcc And Ferreira ,Lcs; Mutagenicity Of Nifurtimox And Benznidazole In The Salmonella/Microsome Assay; Braz. J. Med. Biol. Res. 19(1):19-25, 1986
2578-75-8	n-(5-(5-nitro-2-furanyl)-1,3,4-thiadiazol-2-yl)acetamide	CC(=O)Nc1nnc(s1)-c1ccc(o1)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240
531-82-8	n-(4-(5-nitro-2-furyl)-2-thiazolyl)acetamide	CC(=O)Nc1nc(cs1)-c1ccc(o1)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240; CCRIS database,Toxnet databases
51325-35-0	n,n'-[6-(5-nitro-2-furyl)-s-triazine-2,4-diyl]bisacetamide	CC(=O)Nc1nc(NC(C)=O)nc(n1)-c1ccc(o1)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240
19387-91-8	tinidazole	CCS(=O)(=O)CCn1c(C)ncc1[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	CCRIS database,Toxnet databases: Gupta, Rl., Vats, V. And Juneja, Tr.; Activation Of Tinidazole, An Antiprotozoal Drug To A Mutagen By Mammalian Liver S9; Mutat. Res. 370(3-4):195-201, 1996
67-20-9	Nitrofurantoin	[O-][N+](=O)c1ccc(C=NN2CC(=O)NC2=O)o1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Mccann, J., Choi, E., Yamasaki, E. And Ames, Bn.; Detection Of Carcinogens As Mutagens In The Salmonella/Microsome Test: Assay Of 300 Chemicals; Proc. Natl. Acad. Sci. Usa 72(12):5135-5139, 1975; U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240
59-87-0	Nitrofurazone	NC(=O)NN=Cc1ccc(o1)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240
*10006-72-0	N2-(3-cyano-5-nitro-2-thienyl)-N1,N1-dimethylformamidine	CN(C)\C=N\c1sc(cc1C#N)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html.
*10020-47-4	2-amino-4-(4-aminophenyl)thiophene-3-carbonitrile	Nc1ccc(cc1)-c1csc(N)c1C#N	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html.
122063-39-2	acetic acid 4-[ethyl[4-(3-acetyl-5-nitro-2-thienylazo)-3-methylphenyl]amino]butyl ester	CCN(CCCCOC(C)=O)c1ccc(\N=N\c2sc(cc2C(C)=O)[N+]([O-])=O)c(C)c1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html.
167940-11-6	2'-(3-acetyl-5-nitro-2-thienylazo)-5'-diethylaminoacetoanilide	CCN(CC)c1ccc(\N=N\c2sc(cc2C(C)=O)[N+]([O-])=O)c(NC(C)=O)c1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html.
174072-89-0	ethyl 2-amino-4-methyl-5-(4-nitrophenyl)thiophene-3-carboxylate	CCOC(=O)c1c(N)sc(c1C)-c1ccc(cc1)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html.
56387-09-8	2-amino-5-nitro-3-thiophenecarbonitrile	Nc1sc(cc1C#N)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html.
57531-37-0	2-chloro-4-nitroimidazole	[O-][N+](=O)c1cnc(Cl)[nH]1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html.
70693-64-0	N,N-diethyl-3-methyl-4-[(5-nitro-1,3-thiazol-2-yl)diazenyl]aniline	CCN(CC)c1ccc(\N=N\c2ncc(s2)[N+]([O-])=O)c(C)c1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html.