CAS Chem.name Chem.SMILES #Observed Mutagenicity Bioassay - Reference(s) - 55-18-5 N-Nitrosodiethylamine CCN(CC)N=O in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) P&G Inventory; U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240 59-89-2 N-nitrosomorpholine O=NN1CCOCC1 in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Zeiger, E., et. al. Environ. Mol. Mutagen. 19(Suppl.21):2-141, 1992 62-75-9 N-nitrosodimethylamine CN(C)N=O in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) P&G Inventory 100-75-4 N-Nitrosopiperidine O=NN1CCCCC1 in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) P&G Inventory; U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240 921-14-2 1,1-bis(1-methylethyl)-hydrazine CC(C)N(N)C(C)C in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Aagaard Nielsen, P. et. al.; Mutagenic Activity Of Nine N,N-Disubstituted Hydrazines In The Salmonella/ Mammalian Microsome Assay; Mutat. Res. 278(4):215-226, 1992 7247-89-4 Piperidine, 2-methyl-N-nitroso- CC1CCCCN1N=O in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240 3817-11-6 n-butyl-n-(4-hydroxybutyl)nitrosamine;4-(butylnitrosoamino)-1-butanol CCCCN(CCCCO)N=O in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Mutation Research, 168 (1986) 69-240 55557-00-1 1h-1,4-diazepine, hexahydro-1,4-dinitroso- O=NN1CCCN(N=O)CC1 in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Mutation Research, 168 (1986) 69-240 140-79-4 dinitrosopiperazine O=NN1CCN(N=O)CC1 in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Mutation Research, 168 (1986) 69-240 924-16-3 n,n-dibutylnitrosamine;nitrosodibutylamine CCCCN(CCCC)N=O in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Mutation Research, 168 (1986) 69-240 621-64-7 N,N-dipropylnitrosamine CCCN(CCC)N=O in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Mutation Research, 168 (1986) 69-240 937-40-6 n-methyl-n-benzylnitrosamine CN(Cc1ccccc1)N=O in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) CCRIS database,Toxnet databases 16543-55-8 (S)-N'-Nitrosonornicotine O=NN1CCCC1c1cccnc1 in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Padma, P.R.,et al. Cancer Lett., 1989, 46(3), 173 - 180 5632-47-3 N-nitrosopiperazine O=NN1CCNCC1 in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Zeiger E, Legator MS, Lijinsky W., Mutagenicity of N-nitrosopiperazines for Salmonella typhimurium in the host-mediated assay. Cancer Res. 1972 Jul;32(7):1598-9. 930-55-2 N-nitrosopyrrolidine O=NN1CCCC1 in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) CCRIS database,Toxnet databases 64091-91-4 4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone CN(CCCC(=O)c1cccnc1)N=O in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) CCRIS database,Toxnet databases 484-23-1 Dihydralazine NNc1nnc(NN)c2ccccc12 in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Chlopkiewicz, B., Ejchart, A. and Marczewska, J.; Studies On The Mechanism of Mutagenicity and Genotoxicity Induced by Dihydralazine; Acta Biochim. Pol. 42(3):291-295, 1995 1116-54-7 N-Nitrosodiethanolamine OCCN(CCO)N=O in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) P&G Inventory 114-83-0 1-Acetyl-2-phenylhydrazine CC(=O)NNc1ccccc1 in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 1576-35-8 p-Toluenesulfonyl Hydrazide Cc1ccc(cc1)S(=O)(=O)NN in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) P&G Inventory; Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25 100-63-0 Phenylhydrazine NNc1ccccc1 in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Japan; Mutagenicity Test Data of Existing Chemical Substances Based on The Toxicity Investigation of The Industrial Safety and Health Law; (Suppl. 2), 2000; Watanabe, K, et. al.; Comparisons On Chemically-Induced Mutation Among Four Strains, Salmonella Typhimurium TA102 And TA2638, And Escherichia Coli Wp2/Pkm101 And Wp2 Uvra/Pkm101: Collaborative Study II; Mutat. Res. 412(1):17-31, 1998 54-85-3 4-Pyridinecarboxylic acid, hydrazide NNC(=O)c1ccncc1 in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Braun, R., Jaekel, Hp., and Schoeneich, J.; Genetic Effects of Isoniazid and the Relationship to in Vivo And In Vitro Biotransformation; Mutat. Res. 137(2-3): 61-69, 1984 100-16-3 4-Nitrophenylhydrazine NNc1ccc(cc1)[N+]([O-])=O in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Kawai, A., Goto, S., Matsumoto, Y. and Matsushita, H.; Mutagenicity of Aliphatic and Aromatic Nitro Compounds; Sangyo Igaku 29(1):34-55, 1987 109-84-2 2-hydrazinoethanol NNCCO in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) U.S. Environmental Protection Agency, Mutation Research, 168 (1986) 69-240 119-26-6 Hydrazine, (2,4-dinitrophenyl)- NNc1ccc(cc1[N+]([O-])=O)[N+]([O-])=O in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240 304-20-1 Hydralazine_hydrochloride NNc1nncc2ccccc12 in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Kitamura ,J., Mori, H., Sugie, S. and Kawai, K.; Genetic Toxicity of Several Antihypertensive Drugs Possessing a Hydrazine Group; Res. Commun. Chem. Pathol. Pharmacol. 49(3):415-422, 1985 820-75-7 N-Diazoacetylglycine hydrazide NNC(=O)CNC(=O)C=[N+]=[N-] in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240 1068-57-1 acetohydrazide; Acetic acid hydrazide CC(=O)NN in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Bhide, S. V., Bhalerao, E. B., Sarode, A. V. and Maru, G. B.; Mutagenicity and Carcinogenicity of Mono and Diacetyl Hydrazine; Cancer Lett. 23(2):235-240, 1984 20970-16-5 Pyrido(2,3-d)pyridazin-5(6H)-one hydrazone NNc1nncc2ncccc12 in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Morita, T., Naitou, H. and Oishi, E.; Mutagenicity of Condensed Pyridazines with Different Substituents; Biol. Pharm. Bull. 18(2):363-367, 1995 23590-73-0 Pyrido(2,3-d)pyridazin-8(7H)-one hydrazone NNc1nncc2cccnc12 in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Morita, T., Naitou, H. and Oishi, E.; Mutagenicity of Condensed Pyridazines with Different Substituents; Biol. Pharm. Bull. 18(2):363-367, 1995 27758-60-7 N,N-Di(p-tolyl)hydrazine Cc1ccc(cc1)N(N)c1ccc(C)cc1 in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Aagaard Nielsen, P. et. al.; Mutagenic Activity Of Nine N,N-Disubstituted Hydrazines In The Salmonella/ Mammalian Microsome Assay; Mutat. Res. 278(4):215-226, 1992 28860-95-9 Carbidopa C[C@](Cc1ccc(O)c(O)c1)(NN)C(O)=O in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Kitamura ,J., Mori, H., Sugie, S. and Kawai, K.; Genetic Toxicity of Several Antihypertensive Drugs Possessing a Hydrazine Group; Res. Commun. Chem. Pathol. Pharmacol. 49(3):415-422, 1985 64000-73-3 Pildralazine CC(O)CN(C)c1ccc(NN)nn1 in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Glatt, H. And Oesch, F.; Propyldazine is Mutagenic in Salmonella Typhimurium and Escherichia Coli: Distinct Specificity for Strains TA1537 and TA97; Teratog. Carcinog. Mutagen. 5(5):339-345, 1985 162022-88-0 Pyrido(3,4-d)pyridazin-1(2H)-one hydrazone NNc1nncc2cnccc12 in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Morita, T., Naitou, H. and Oishi, E.; Mutagenicity of Condensed Pyridazines with Different Substituents; Biol. Pharm. Bull. 18(2):363-367, 1995 162022-89-1 Pyrido(3,4-d)pyridazin-4(3H)-one hydrazone NNc1nncc2ccncc12 in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Morita, T., Naitou, H. and Oishi, E.; Mutagenicity of Condensed Pyridazines with Different Substituents; Biol. Pharm. Bull. 18(2):363-367, 1995 7327-87-9 Dihydralazine_sulfate NNc1c2ccccc2c(NN)nn1_OS(O)(=O)=O in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Glatt, H. And Oesch, F.; Propyldazine is Mutagenic in Salmonella Typhimurium and Escherichia Coli: Distinct Specificity for Strains TA1537 and TA97; Teratog. Carcinog. Mutagen. 5(5):339-345, 1985 135086-97-4 3-Amino-5H-1,2,3-triazin(5,4b)indol-4-one NN1N=Nc2c([nH]c3ccccc32)C1=O in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Lopez-De-Cerain, A., Garcia, E. and Gullon, A.; Influence of The Triazine Ring on the Mutagenicity of Triazinoindoles and some Congeners; Mutagenesis 7(1):37-39, 1992 122341-55-3 Diazo-N-nitrosoetilefrin CCN(CC(O)C1C=CC(=[N+]=[N-])C(=O)C=1)N=O in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Kikugawa, K., Kato, T. and Takeda, Y.; Formation of a Highly Mutagenic Diazo Compound from the Bamethan-Nitrite Reaction; Mutat. Res. 177(1):35-43, 1987 70-25-7 N-Methyl-N'-Nitro-N-Nitrosoguanidine CN(N=O)C(=N)N[N+]([O-])=O in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Diehl, M. And Fort, F.; Spiral Salmonella Assay: Validation Against The Standard Pour-Plate Assay; Environ. Mol. Mutagen. 27(3):227-236, 1996 154-93-8 carmustine O=C(NCCCl)N(CCCl)N=O in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) U.S. Environmental Protection Agency, Mutation Research, 168 (1986) 69-240 80-51-3 p,p'-Oxybis(benzenesulfonyl hydrazide) NNS(=O)(=O)c1ccc(Oc2ccc(cc2)S(=O)(=O)NN)cc1 in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) NIHS Japan 644-21-3 1-ethyl-1-phenyl-hydrazine CCN(N)c1ccccc1 in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Aagaard Nielsen, P. et. al.; Mutagenic Activity Of Nine N,N-Disubstituted Hydrazines In The Salmonella/ Mammalian Microsome Assay; Mutat. Res. 278(4):215-226, 1992 60-34-4 Methylhydrazine CNN in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Japan Chemical Industry Ecology- Toxicology And Information Center, Japan; Mutagenicity Test Data Of Existing Chemical Substances Based On The Toxicity Investigation Of The Industrial Safety And Health Law; 1996; Poso, A., Von Wright, A. And Gynther, J.; An Empirical And Theoretical Study On Mechanisms Of Mutagenic Activity Of Hydrazine Compounds; Mutat. Res. 322(1,2):63-71, 1995 110963-29-6 3-Aminoindol-2-carbohydrazide NNC(=O)c1[nH]c2ccccc2c1N in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Lopez-De-Cerain, A., Garcia, E. and Gullon, A.; Influence of The Triazine Ring on the Mutagenicity of Triazinoindoles and some Congeners; Mutagenesis 7(1):37-39, 1992 14448-67-0 MBTH_hydrochloride Cl_CN1c2ccccc2SC1=NN in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Ballantyne, B. et al; The Acute Toxicity And Mutagenic Potential Of 3-Methyl-2-Benzothiazolinone Hydrazone; Toxicol. Ind. Health 4(1):23-37, 1988; Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25 56413-75-3 o-Nitrophenylhydrazine hydrochloride [H+].[Cl-].NNc1ccccc1[N+]([O-])=O in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Kawai, A, Goto, S, Matsumoto, Y And Matsushita, H; Sangyo Igaku 29(1):34-55, 1987; Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25 116539-70-9 2,4-Cyclohexadien-1-one, 4-(2-(butylnitrosamino)-1-hydroxyethyl)-6- CCCCN(C[C@H](O)C1C=CC(=O)C(C=1)=[N+]=[N-])N=O in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Kikugawa, K., Kato, T. and Takeda, Y.; Formation of a Highly Mutagenic Diazo Compound from the Bamethan-Nitrite Reaction; Mutat. Res. 177(1):35-43, 1987 2757-90-6 Agaritine;beta-n-[gamma-l(+)-glutamyl]-4-hydroxymethylphenylhydrazine NC(CCC(=O)NNc1ccc(CO)cc1)C(O)=O in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Friedrich, U., B. Fischer, J. Luthy, D. Hann, Chr. Schlatter, Fr. E. Wurgler, The Mutagenic Activity of Agaritine – A Constituent of the Cultivated Mushroom Agaricus Bisporus – and Its Derivatives Detected with the Salmonella/Mammalian Microsome Assay (Ames test), Z. Lebensm. Unters Forsch 183 (1986), 85 – 89 869-01-2 n-butyl-n-nitrosourea; 1-butyl-1-nitrosourea CCCCN(C(N)=O)N=O in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) CCRIS database,Toxnet databases 13909-09-6 Semustine; 1-(2-Chloroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea CC1CCC(NC(=O)N(CCCl)N=O)CC1 in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) CCRIS database,Toxnet databases 38434-77-4 ethylnitrosocyanamide CCN(C#N)N=O in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240; CCRIS database,Toxnet databases: Lee, K., B. Gold, S. S. Mirvish, Mutagenicity of 22 N-Nitrosamides and Related Compounds for Salmonella typhimurium TA1535, Mutat. Res. 48 (1977), 131 – 138 759-73-9 1-ethyl-1-nitrosourea CCN(C(N)=O)N=O in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240 3570-75-0 nifurthiazole;formic acid 2-[4-(5-nitro-2-furyl)-2-thiazolyl]hydrazide [O-][N+](=O)c1ccc(o1)-c1csc(NNC=O)n1 in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240 92118-27-9 fotemustine CCOP(=O)(C(C)NC(=O)N(CCCl)N=O)OCC in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) CCRIS database,Toxnet databases 18774-85-1 n-hexylnitrosourea;urea, 1-hexyl-1-nitroso- CCCCCCN(C(N)=O)N=O in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240 13743-07-2 1-(2-hydroxyethyl)-1-nitrosourea NC(=O)N(CCO)N=O in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240 33868-17-6 methylnitrosocyanamide CN(C#N)N=O in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240 16813-36-8 1-nitroso-5,6-dihydrouracil O=C1CCN(N=O)C(=O)N1 in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240 614-95-9 nitrosoethylurethane CCN(C(=O)OCC)N=O in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240 56222-35-6 3-hydroxy-1-nitrosopyrrolidine OC1CCN(N=O)C1 in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240 55556-92-8 N-Nitroso-1,2,3,6-tetrahydropyridine O=NN1CCC=CC1 in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240 13010-07-6 Propyl-N'-nitro-N-nitrosoguanidine CCCN(N=O)C(=N)N[N+]([O-])=O in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240 816-57-9 Propylnitrosourea CCCN(C(N)=O)N=O in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) CCRIS database,Toxnet databases 6804-07-5 carbadox COC(=O)NN=Cc1c[n+]([O-])c2ccccc2[n+]1[O-] in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Beutin, L., Preller, E., Kowalski, B., Mutagenicity of Quindoxin, Its Metabolites, and Two Substituted Quinoxaline-di-N-Oxides. Antimicrob. Agents Chemother., 1981, 20(3), 336 - 343 59-87-0 Nitrofurazone NC(=O)NN=Cc1ccc(o1)[N+]([O-])=O in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240 *10006-36-1 N'-(4-aminophenyl)-2-(4-tert-pentylphenoxy)acetohydrazide CCC(C)(C)c1ccc(OCC(=O)NNc2ccc(N)cc2)cc1 in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html. *10007-29-9 2-[2-methoxy-4-[3-[2-(trichloroacetyl)hydrazino]-3-oxo-1-propenyl]phenoxy]acetic acid methyl ester COC(=O)COc1ccc(\C=C\C(=O)NNC(=O)C(Cl)(Cl)Cl)cc1OC in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html. *10008-21-8 2-[2-chloro-4-fluoro-5-(5-hydroxy-1-methyl-1H-pyrazole-3-yl)phenoxy]-N-methylacetamide CNC(=O)COc1cc(c(F)cc1Cl)-c1cc(O)n(C)n1 in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html. *10008-53-3 1-cyclohexylethanone 3-fluoro-p-tolylhydrazone C\C(=N/Nc1ccc(C)c(F)c1)C1CCCCC1 in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html. *10117-43-3 (4E)-dec-4-enohydrazide CCCCC\C=C\CCC(=O)NN in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html. 100133-09-3 3-methyl-2-butanone 3-pyridylhydrazone CC(C)C(/C)=N/Nc1cccnc1 in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html. 101907-41-9 phenyl N-[4-(2-formylhydrazinyl)phenyl]carbamate O=CNNc1ccc(NC(=O)Oc2ccccc2)cc1 in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html. 107746-30-5 3-hydrazino-N,N-dimethylpropanamide CN(C)C(=O)CCNN in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html. 112858-31-8 3-(2-ethylidenehydrazinyl)-N,N-dimethylpropanamide C\C=N\NCCC(=O)N(C)C in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html. 1858-99-7 benzaldehyde (4-methylphenyl)hydrazone Cc1ccc(N\N=C\c2ccccc2)cc1 in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html. 2538-61-6 2,6-dimethylphenylhydrazine hydrochloride Cc1cccc(C)c1NN_Cl in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html. 40119-17-3 (3,4-dimethoxyphenyl)hydrazine hydrochloride Cl_COc1ccc(NN)cc1OC in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html. 42166-50-7 3-pyridylhydrazine NNc1cccnc1 in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html. 5458-77-5 undec-10-enehydrazide NNC(=O)CCCCCCCCC=C in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html. 60481-51-8 3,4-dimethylphenylhydrazine hydrochloride Cc1ccc(NN)cc1C_Cl in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html. 63402-26-6 1-formyl-2-(4-aminophenyl)hydrazine Nc1ccc(NNC=O)cc1 in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html. 687971-90-0 3-fluoro-4-methylphenylhydrazine Cc1ccc(NN)cc1F in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html. 728010-60-4 1-(1-amino-1H-pyrrole-2-yl)ethanone hydrochloride CC(=O)C1=CC=CN1N_Cl in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html. 75753-05-8 N-[4-[(3-nitrophenyl)sulfonylamino]anilino]formamide [O-][N+](=O)c1cccc(c1)S(=O)(=O)Nc1ccc(NNC=O)cc1 in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html. 77458-54-9 1-chloro-3-[2-(4-chlorophenyl)hydrazono]-2-propanone ClCC(=O)\C=N\Nc1ccc(Cl)cc1 in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html. 530-50-7 1,1-Diphenylhydrazine NN(c1ccccc1)c1ccccc1 in vitro Ames negative Bacterial Reverse Mutation Assay (e.g. Ames Test) Nielsen, P.A., Lagersted, A., Danielsen, S., Jensen, A.A., Hart, J., Larsen, J.C., Mutagenic activity of nine N,N-disubstituted hydrazines in the Salmonella/mammalian microsome assay. Mutat. Res., 1992, 278(4), 215-226. 5802-60-8 1,1-bis(phenylmethyl)-hydrazine NN(Cc1ccccc1)Cc1ccccc1 in vitro Ames negative Bacterial Reverse Mutation Assay (e.g. Ames Test) CCRIS database,Toxnet databases; Nielsen, P. A., A. Lagersted, S. Danielsen, et al. Mutat. Res. 278 (1992),215 - 226 7068-83-9 N-Methyl-N-nitroso-1-butanamine CCCCN(C)N=O in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) U.S. Environmental Protection Agency, Mutation Research, 168 (1986) 69-240 86-54-4 Hydralazine N\N=C1/NN=Cc2ccccc21 in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Chlopkiewicz, B., et al; Acta Pol. Pharm. 52(1):31-33, 1995; Mcqueen, C. A., et al.; Toxicol. Appl. Pharmacol. 118(1):135-138, 1993; Morita, T., et al; Biol. Pharm. Bull. 18(2):363-367, 1995; Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25 61499-28-3 N-Nitroso(2-hydroxypropyl)(2-oxopropyl)amine CC(O)CN(CC(C)=O)N=O in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) PubChem database, https://pubchem.ncbi.nlm.nih.gov 89911-79-5 n-nitroso-2,3-dihydroxypropyl-2-hydroxypropylamine CC(O)CN(CC(O)CO)N=O in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Mori,Y, Yamazaki,H, Toyoshi,K, Denda,A And Konishi,Y., Mutagenic Activation Of Carcinogenic N-Nitrosopropylamines By Liver S9 Fractions From Mice, Rats And Hamsters. Evidence For A Cytochrome P-450-Dependent Reaction; Carcinogenesis 7(3):375-379, 1986 101-25-7 N,N-dinitrosopentamethylenetetramine O=NN1CN2CN(C1)CN(N=O)C2 in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) P&G Inventory 7090-25-7 Nitrosocarbaryl CN(C(=O)Oc1cccc2ccccc12)N=O in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) U.S. Environmental Protection Agency, Mutation Research, 168 (1986) 69-240 38777-13-8 nitroso-baygon;n-nitrosopropoxur CC(C)Oc1ccccc1OC(=O)N(C)N=O in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) U.S. Environmental Protection Agency, Mutation Research, 168 (1986) 69-240 684-93-5 n-methyl-n-nitrosourea CN(C(N)=O)N=O in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) CCRIS database,Toxnet databases 18883-66-4 streptozotocin CN(C(=O)NC1C(O)C(O)C(CO)OC1O)N=O in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) U.S. Environmental Protection Agency, Mutation Research, 168 (1986) 69-240