CAS	Chem.name	Chem.SMILES	#Observed Mutagenicity	Bioassay - 	Reference(s) -
7247-89-4	Piperidine, 2-methyl-N-nitroso-	CC1CCCCN1N=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240
55557-00-1	1h-1,4-diazepine, hexahydro-1,4-dinitroso-	O=NN1CCCN(CC1)N=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240
140-79-4	dinitrosopiperazine	O=NN1CCN(CC1)N=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240
5336-53-8	n-nitrosodibenzylamine	O=NN(Cc1ccccc1)Cc1ccccc1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	CCRIS database,Toxnet databases; U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240
937-40-6	n-methyl-n-benzylnitrosamine	CN(Cc1ccccc1)N=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	SINGER,GM, ANDREWS,AW AND GUO,SM; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP OF THE MUTAGENICITY OF SUBSTITUTED N-NITROSO-N-BENZYLMETHYLAMINES: POSSIBLE IMPLICATIONS FOR CARCINOGENICITY; J. MED. CHEM. 29(1):40-44, 1986
101-25-7	N,N-dinitrosopentamethylenetetramine	O=NN1CN2CN(C1)CN(C2)N=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	P&G Inventory; Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
135-20-6	Cupferron	ON(N=O)c1ccccc1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	P&G Inventory; Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
70-25-7	N-Methyl-N'-Nitro-N-Nitrosoguanidine	CN(N=O)C(=N)N[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Diehl, M. And Fort, F.; Spiral Salmonella Assay: Validation Against The Standard Pour-Plate Assay; Environ. Mol. Mutagen. 27(3):227-236, 1996
154-93-8	carmustine	ClCCNC(=O)N(CCCl)N=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	U.S. Environmental Protection Agency, Mutation Research, 168 (1986) 69-240; Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
149573-80-8	(1-Nitroso-1h-imidazol-4-yl)acetohydroxamic acid	ONC(=O)Cc1cn(cn1)N=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Danno, G., et. al.; A Mutagen From Histidine Reacted With Nitrite; J. Agric. Food Chem. 41(7):1090-1093, 1993
7090-25-7	Nitrosocarbaryl	CN(N=O)C(=O)Oc1cccc2ccccc12	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240; Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
869-01-2	n-butyl-n-nitrosourea; 1-butyl-1-nitrosourea	CCCCN(N=O)C(N)=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	CCRIS database,Toxnet databases: Janzowski, C, Jacob, D, Henn, I, Zankl, H, Pool-Zobel, Bl, Wiessler, M And Eisenbrand, G;Mechanism Of Action Of The Urinary Bladder Carcinogen N-Nitrosobutyl-3-Carboxypropylamine; Iarc Sci. Publ. 105(Relevance Hum. Cancer N-Nitroso Compd., Tob. Mycotoxins):332-338, 1991
13909-09-6	Semustine; 1-(2-Chloroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea	CC1CCC(CC1)NC(=O)N(CCCl)N=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	CCRIS database,Toxnet databases: Ashby, J, et. el.; Mutagenicity to Salmonella, Drosophila and the Mouse Bone Marrow of the Human Antineoplastic Agent Fotemustine: Prediction Of Carcinogenic Potency; Mutat. Res. 286(1):101- 109, 1993
63885-23-4	n-ethyl-n'-nitro-n-nitroguanidine	CCN=C(N)N(N=O)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	CCRIS database,Toxnet databases: Nakamura, S.-i., Y. Oda, Ts. Shimada, I. Oki, K. Sugimoto, SOS-Inducing Activity of Chemical Carcinogens and Mutagens in Salmonella typhimurium TA1535/pSK 1002: Examination with 151 Chemicals, Mutat. Res. 192 (1987), 239 – 246
38434-77-4	ethylnitrosocyanamide	CCN(N=O)C#N	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240; CCRIS database,Toxnet databases: Lee, K., B. Gold, S. S. Mirvish, Mutagenicity of 22 N-Nitrosamides and Related Compounds for Salmonella typhimurium TA1535, Mutat. Res. 48 (1977), 131 – 138
759-73-9	1-ethyl-1-nitrosourea	CCN(N=O)C(N)=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	CCRIS database,Toxnet databases: Ashby, J., Tinwell, H. and Callander, Rd.; Activity of Urethane and N,N-Dimethylurethane in the Mouse Bone-Marrow Micronucleus Assay: Equivalence of Oral and Intraperitoneal Routes of Exposure; Mutat. Res. 245(3):227-230, 1990
92118-27-9	fotemustine	CCOP(=O)(OCC)C(C)NC(=O)N(CCCl)N=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	CCRIS database,Toxnet databases: Ashby, J, et. el.; Mutagenicity to Salmonella, Drosophila and the Mouse Bone Marrow of the Human Antineoplastic Agent Fotemustine: Prediction Of Carcinogenic Potency; Mutat. Res. 286(1):101- 109, 1993
18774-85-1	n-hexylnitrosourea;urea, 1-hexyl-1-nitroso-	CCCCCCN(N=O)C(N)=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240
13743-07-2	1-(2-hydroxyethyl)-1-nitrosourea	NC(=O)N(CCO)N=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240
63412-06-6	n-methyl-n-nitrosobenzamide	CN(N=O)C(=O)c1ccccc1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240
33868-17-6	methylnitrosocyanamide	CN(N=O)C#N	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240
38777-13-8	nitroso-baygon;n-nitrosopropoxur	CC(C)Oc1ccccc1OC(=O)N(C)N=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240
16813-36-8	1-nitroso-5,6-dihydrouracil	O=NN1CCC(=O)NC1=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240
614-95-9	nitrosoethylurethane	CCOC(=O)N(CC)N=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240
42579-28-2	1-nitrosohydantoin	O=NN1CC(=O)NC1=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240
56222-35-6	3-hydroxy-1-nitrosopyrrolidine	OC1CCN(C1)N=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240
684-93-5	n-methyl-n-nitrosourea	CN(N=O)C(N)=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	CCRIS database,Toxnet databases
13010-07-6	Propyl-N'-nitro-N-nitrosoguanidine	CCCN(N=O)C(=N)N[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	CCRIS database,Toxnet databases; U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240
816-57-9	Propylnitrosourea	CCCN(N=O)C(N)=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	CCRIS database,Toxnet databases; Ukawa-Ishikawa, S, Sawada, A, Kasuya, A And Mochizuki, M; Mutagenicity Of Isomeric Alkanediazotates, Precursors For Ultimate Alkylating Species Of Carcinogenic N-Nitroso Compounds; Mutat. Res. 412(1):99-107, 1998
18883-66-4	streptozotocin	CN(N=O)C(=O)NC1C(O)OC(CO)C(O)C1O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	CCRIS database,Toxnet databases; U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240
61499-28-3	N-Nitroso(2-hydroxypropyl)(2-oxopropyl)amine	CC(O)CN(CC(C)=O)N=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	PubChem database, https://pubchem.ncbi.nlm.nih.gov
60599-38-4	Nitrosobis(2-oxopropyl)amine	CC(=O)CN(CC(C)=O)N=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	PubChem database, https://pubchem.ncbi.nlm.nih.gov
136587-13-8	Spermine nitric oxide complex	NCCCNCCCCN(CCCN)N(O)N=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R., Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
105553-32-0	1-(2-Hydroxyimino-3-Oxobutyryl)-2-Methyl-2-Nitroso-1-Phenylhydrazine	CC(=O)C(\C(=O)N(c1ccccc1)N(C)N=O)=N/O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	CCRIS database,Toxnet databases
138475-09-9	Sodium Z-1-(N,N-Diethylamino)Diazen-1-Ium-1,2-Diolate	CCN(CC)N(N=O)O{-}.[Na]{+}	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	CCRIS database,Toxnet databases