CAS	Chem.name	Chem.SMILES	#Observed Mutagenicity	Bioassay - 	Reference(s) -
60-09-3	Solvent Yellow 1	Nc1ccc(cc1)N=Nc1ccccc1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240; P&G Inventory
60-11-7	4-(dimethylamino)azobenzene	CN(C)c1ccc(cc1)N=Nc1ccccc1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Zeiger, E., et. al.; Salmonella Mutagenicity Tests: III. Results From The Testing Of 255 Chemicals; Environ. Mol. Mutagen. 9(Suppl.9):1-110, 1987
51868-46-3	c.i. disperse blue 373	COc1cc(N=Nc2c(Br)cc(cc2[N+]([O-])=O)[N+]([O-])=O)c(NC(C)=O)cc1N(CC=C)CC=C	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	de Aragao Umbuzeiro, G., Freeman, H.S., Warren, S.H., de Oliveira, D.P., Terao, Y., Watanabe, T., Claxton, L.D., The contribution of azo dyes to the mutagenic activity of the Cristais River. Chemosphere, 2005, 60(1), 55-64.
3468-63-1	Pigment orange 5	Oc1ccc2ccccc2c1N=Nc1ccc(cc1[N+]([O-])=O)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	P&G Inventory; U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240
3025-77-2	1-((4-Nitrophenyl)azo)-2-naphthalenamine	Nc1ccc2ccccc2c1N=Nc1ccc(cc1)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	P&G Inventory; Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
6530-27-4	N-Hydroxy-4-aminoazobenzene	ONc1ccc(cc1)\N=N/c1ccccc1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240; Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
13301-61-6	c.i. disperse orange 37	CCN(CCC#N)c1ccc(cc1)N=Nc1c(Cl)cc(cc1Cl)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	de Aragao Umbuzeiro, G., Freeman, H.S., Warren, S.H., de Oliveira, D.P., Terao, Y., Watanabe, T., Claxton, L.D., The contribution of azo dyes to the mutagenic activity of the Cristais River. Chemosphere, 2005, 60(1), 55-64.
14097-03-1	c.i. basic red 18	CCN(CC[N+](C)(C)C)c1ccc(cc1)N=Nc1ccc(cc1Cl)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Bakshi, D. and Sharma, P.; Genotoxicity of Textile Dyes Evaluated With Ames Test adn Rec Assay; J. Environ. Pathol. Toxicol. Oncol. 22(2):101-109, 2003
56548-64-2	2-[(2-bromo-4,6-dinitrophenyl)azo]-5-(diethylamino)-4-methoxyacetanilde	CCN(CC)c1cc(NC(C)=O)c(cc1OC)N=Nc1c(Br)cc(cc1[N+]([O-])=O)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	de Aragao Umbuzeiro, G., Freeman, H., Warren, S.H., Kummrow, F., Claxton, L.D., Mutagenicity evaluation of the commercial product CI Disperse Blue 291 using different protocols of the Salmonella assay. Food Chem. Toxicol., 2005, 43(1), 49-56.
2872-52-8	disperse red 1	CCN(CCO)c1ccc(cc1)N=Nc1ccc(cc1)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Ferraz, E.R., Umbuzeiro, G.A., de-Almeida, G., Caloto-Oliveira, A., Chequer, F.M., Zanoni, M.V., Dorta, D.J., Oliveira, D.P., Differential toxicity of Disperse Red 1 and Disperse Red 13 in the Ames test, HepG2 cytotoxicity assay, and Daphnia acute toxicity test. Environ. Toxicol., 2011, 26(5), 489-497.
3179-89-3	c.i. disperse red 17	Cc1cc(ccc1N=Nc1ccc(cc1)[N+]([O-])=O)N(CCO)CCO	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	SCCS (Scientific Committee on Consumer Safety), Opinion on Disperse Red 17, 12 December 2013.
23355-64-8	c.i. disperse brown 1	OCCN(CCO)c1ccc(N=Nc2c(Cl)cc(cc2Cl)[N+]([O-])=O)c(Cl)c1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Seifried, H.E., Seifried, R.M., Clarke, J.J., Junghans, T.B., San, R.H., A compilation of two decades of mutagenicity test results with the Ames Salmonella typhimurium and L5178Y mouse lymphoma cell mutation assays. Chem. Res. Toxicol., 2006, 19(5), 627-644.
*10003-23-7	5'-[N-ethyl-N-[2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethyl]amino]-2'-(4-nitrophenylazo)acetanilide	CCN(CCN1C(=O)C=CC1=O)c1ccc(\N=N\c2ccc(cc2)[N+]([O-])=O)c(NC(C)=O)c1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html.
10009-75-3	6-amino-5-[(2-hydroxy-4-nitrophenyl)azo]-N-methyl-2-naphthalenesulfonamide	CNS(=O)(=O)c1ccc2c(ccc(N)c2\N=N\c2ccc(cc2O)[N+]([O-])=O)c1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html. Divizion of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html; Last update; June 2019
*10009-78-9	5-(diethylamino)-5'-nitro-(2,2'-azobisphenol)	CCN(CC)c1ccc(\N=N\c2ccc(cc2O)[N+]([O-])=O)c(O)c1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html. Divizion of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html; Last update; June 2019
*10016-86-7	N-hexadecyl-4-[5-tert-butyl-4-[4-[3-[8-(2-cyano-4-nitrophenylazo)-6-(propionylamino)-5-hydroxy-1-naphthylaminosulfonyl]phenylsulfonylamino]phenoxymethyl]-3-oxo-2,3-dihydroisoxazole-2-yl]-3-nitrobenzamide	CCCCCCCCCCCCCCCCNC(=O)c1ccc(N2OC(=C(COc3ccc(NS(=O)(=O)c4cccc(c4)S(=O)(=O)Nc4cccc5c(O)c(NC(=O)CC)cc(\N=N\c6ccc(cc6C#N)[N+]([O-])=O)c45)cc3)C2=O)C(C)(C)C)c(c1)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html. Divizion of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html; Last update; June 2019
1021394-33-1	3-[N-benzyl-4-[(2-cyano-4-nitrophenyl)azo]anilino]propanoic acid 2-oxopropyl ester	CC(=O)COC(=O)CCN(Cc1ccccc1)c1ccc(cc1)\N=N\c1ccc(cc1C#N)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html. Divizion of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html; Last update; June 2019
151285-25-5	2-[3-(2,6-dichloro-4-nitrophenylazo)-9H-carbazole-9-yl]ethanol	OCCn1c2ccccc2c2cc(ccc21)\N=N\c1c(Cl)cc(cc1Cl)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html. Divizion of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html; Last update; June 2019
170778-70-8	2'-(2-chloro-4,6-dinitrophenylazo)-5'-ethylamino-4'-methoxyacetanilide	CCNc1cc(NC(C)=O)c(cc1OC)\N=N\c1c(Cl)cc(cc1[N+]([O-])=O)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html. Divizion of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html; Last update; June 2019
204277-61-2	2-(N-{5-acetamido-4-[(2-chloro-6-cyano-4-nitrophenyl)diazenyl]-2-methoxyphenyl}-N-(methoxycarbonylmethyl)amino)propanoic acid methyl	COC(=O)CN(C(C)C(=O)OC)c1cc(NC(C)=O)c(cc1OC)\N=N\c1c(Cl)cc(cc1C#N)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html. Divizion of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html; Last update; June 2019
213831-09-5	N-[5-(acetylamino)-4-[(2-chloro-4,6-dinitrophenyl)azo]-2-methoxyphenyl]-N-(2-ethoxy-2-oxoethyl)glycine methyl ester	CCOC(=O)CN(CC(=O)OC)c1cc(NC(C)=O)c(cc1OC)\N=N\c1c(Cl)cc(cc1[N+]([O-])=O)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html. Divizion of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html; Last update; June 2019
22578-86-5	2'-(2-bromo-4,6-dinitrophenylazo)-5'-[N-(2-cyanoethyl)-N-ethylamino]-4'-methoxyacetanilide	CCN(CCC#N)c1cc(NC(C)=O)c(cc1OC)\N=N\c1c(Br)cc(cc1[N+]([O-])=O)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html. Divizion of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html; Last update; June 2019
52583-35-4	5'-[bis(2-methoxyethyl)amino]-2'-[(2-cyano-4,6-dinitrophenyl)azo]acetoanilide	COCCN(CCOC)c1ccc(\N=N\c2c(cc(cc2[N+]([O-])=O)[N+]([O-])=O)C#N)c(NC(C)=O)c1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html. Divizion of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html; Last update; June 2019
52583-53-6	2'-(2,6-dibromo-4-nitrophenylazo)-5'-diethylaminoacetanilide	CCN(CC)c1ccc(N=Nc2c(Br)cc(cc2Br)[N+]([O-])=O)c(NC(C)=O)c1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html. Divizion of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html; Last update; June 2019
53950-33-7	N-[2-[(2-bromo-4,6-dinitrophenyl)diazenyl]-5-(2-cyanoethylamino)-4-methoxyphenyl]acetamide	COc1cc(\N=N\c2c(Br)cc(cc2[N+]([O-])=O)[N+]([O-])=O)c(NC(C)=O)cc1NCCC#N	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html. Divizion of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html; Last update; June 2019
66557-45-7	N-[2-[(2-chloro-4,6-dinitrophenyl)diazenyl]-5-(diethylamino)phenyl]acetamide	CCN(CC)c1ccc(\N=N\c2c(Cl)cc(cc2[N+]([O-])=O)[N+]([O-])=O)c(NC(C)=O)c1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html. Divizion of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html; Last update; June 2019
79295-99-1	N-[2-[(2-chloro-4,6-dinitrophenyl)diazenyl]-5-(diethylamino)-4-methoxyphenyl]acetamide	CCN(CC)c1cc(NC(C)=O)c(cc1OC)\N=N\c1c(Cl)cc(cc1[N+]([O-])=O)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html. Divizion of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html; Last update; June 2019
96662-24-7	3-[N-benzyl-4-(4-nitrophenylazo)anilino]propiononitrile	[O-][N+](=O)c1ccc(cc1)N=Nc1ccc(cc1)N(CCC#N)Cc1ccccc1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html. Divizion of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html; Last update; June 2019