CAS	Chem.name	Chem.SMILES	#Observed Mutagenicity	Bioassay - 	Reference(s) -
51868-46-3	c.i. disperse blue 373	COc1cc(N=Nc2c(Br)cc(cc2[N+]([O-])=O)[N+]([O-])=O)c(NC(C)=O)cc1N(CC=C)CC=C	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	de Aragao Umbuzeiro, G., Freeman, H.S., Warren, S.H., de Oliveira, D.P., Terao, Y., Watanabe, T., Claxton, L.D., The contribution of azo dyes to the mutagenic activity of the Cristais River. Chemosphere, 2005, 60(1), 55-64.
121-14-2	2,4-Dinitrotoluene	Cc1ccc(cc1[N+]([O-])=O)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
1817-73-8	2-Bromo-4,6-dinitroaniline	Nc1c(Br)cc(cc1[N+]([O-])=O)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	P&G Inventory; Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
3468-63-1	Pigment orange 5	Oc1ccc2ccccc2c1N=Nc1ccc(cc1[N+]([O-])=O)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	P&G Inventory; U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240
618-87-1	Aniline, 3,5-dinitro-	Nc1cc(cc(c1)[N+]([O-])=O)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	P&G Inventory; Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
99-65-0	Benzene, m-dinitro-	[O-][N+](=O)c1cccc(c1)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
99-35-4	Benzene, 1,3,5-trinitro-	[O-][N+](=O)c1cc(cc(c1)[N+]([O-])=O)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	P&G Inventory; Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
70-34-8	1-Fluoro-2,4-dinitrobenzene	[O-][N+](=O)c1ccc(F)c(c1)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	P&G Inventory; Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
88-88-0	Picryl chloride	[O-][N+](=O)c1cc(c(Cl)c(c1)[N+]([O-])=O)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	P&G Inventory; Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
97-02-9	2,4-Dinitroaniline	Nc1ccc(cc1[N+]([O-])=O)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	P&G Inventory; Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
100-25-4	1,4-Dinitrobenzene	[O-][N+](=O)c1ccc(cc1)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	P&G Inventory; Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
119-26-6	Hydrazine, (2,4-dinitrophenyl)-	NNc1ccc(cc1[N+]([O-])=O)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240
97-00-7	1-Chloro-2,4-dinitrobenzene	[O-][N+](=O)c1ccc(Cl)c(c1)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kerklaan, Prm., Bouter, S., et al; Mutagenicity Of Halogenated And Other Substituted Dinitrobenzenes In Salmonella Typhimurium Ta100 And Derivatives Deficient In Glutathione (Ta100/Gsh-) And Nitroreductase (Ta100nr); Mutat. Res. 176(2):171-180, 1987; Kawai, A., Goto, S., Matsumoto, Y. And Matsushita, H.; Mutagenicity Of Aliphatic And Aromatic Nitro Compounds; Sangyo Igaku 29(1):34-55, 1987
584-48-5	1-bromo-2,4-dinitrobenzene	[O-][N+](=O)c1ccc(Br)c(c1)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kerklaan, PRM, et. al.; Mutat. Res. 176(2):171-180, 1987; Gupta, Rl. et. al; Mutat. Res. 381(1):41-47, 1997
709-49-9	1-iodo-2,4-dinitrobenzene	[O-][N+](=O)c1ccc(I)c(c1)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Gupta, Rl., Saini, Bhk. and Juneja, TR.; Nitroreductase Independent Mutagenicity of 1-Halogenated-2,4-Dinitrobenzenes; Mutat. Res. 381(1):41-47, 1997
59283-76-0	2-Hydroxylamino-4,6-dinitrotoluene	Cc1c(NO)cc(cc1[N+]([O-])=O)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Padda, Rs., Wang, Cy., Hughes, JB. and . GN.; Mutagenicity of Trinitrotoluene and Metabolites Formed During Anaerobic Degradation by Clostridium Acetobutylicum Atcc 824; Environ. Toxicol. Chem. 19(12):2871-2875, 2000; Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
606-20-2	2,6-dinitrotoluene	Cc1c(cccc1[N+]([O-])=O)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	CCRIS database,Toxnet databases: Kawai, A, Goto, S, Matsumoto, Y And Matsushita, H; Mutagenicity Of Aliphatic And Aromatic Nitro Compounds; Sangyo Igaku 29(1):34-55, 1987
56548-64-2	2-[(2-bromo-4,6-dinitrophenyl)azo]-5-(diethylamino)-4-methoxyacetanilde	CCN(CC)c1cc(NC(C)=O)c(cc1OC)N=Nc1c(Br)cc(cc1[N+]([O-])=O)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	de Aragao Umbuzeiro, G., Freeman, H., Warren, S.H., Kummrow, F., Claxton, L.D., Mutagenicity evaluation of the commercial product CI Disperse Blue 291 using different protocols of the Salmonella assay. Food Chem. Toxicol., 2005, 43(1), 49-56.
*10006-31-5	2-(5-fluoro-2,4-dinitrophenoxy)acetic acid butyl ester	CCCCOC(=O)COc1cc(F)c(cc1[N+]([O-])=O)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html.
*10016-43-1	N,N-diallyl-2,4-dinitroaniline	[O-][N+](=O)c1ccc(N(CC=C)CC=C)c(c1)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html.
170778-70-8	2'-(2-chloro-4,6-dinitrophenylazo)-5'-ethylamino-4'-methoxyacetanilide	CCNc1cc(NC(C)=O)c(cc1OC)\N=N\c1c(Cl)cc(cc1[N+]([O-])=O)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html.
213831-09-5	N-[5-(acetylamino)-4-[(2-chloro-4,6-dinitrophenyl)azo]-2-methoxyphenyl]-N-(2-ethoxy-2-oxoethyl)glycine methyl ester	CCOC(=O)CN(CC(=O)OC)c1cc(NC(C)=O)c(cc1OC)\N=N\c1c(Cl)cc(cc1[N+]([O-])=O)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html.
22578-86-5	2'-(2-bromo-4,6-dinitrophenylazo)-5'-[N-(2-cyanoethyl)-N-ethylamino]-4'-methoxyacetanilide	CCN(CCC#N)c1cc(NC(C)=O)c(cc1OC)\N=N\c1c(Br)cc(cc1[N+]([O-])=O)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html.
327-92-4	1,5-difluoro-2,4-dinitrobenzene	[O-][N+](=O)c1cc(c(F)cc1F)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html.
52583-35-4	5'-[bis(2-methoxyethyl)amino]-2'-[(2-cyano-4,6-dinitrophenyl)azo]acetoanilide	COCCN(CCOC)c1ccc(\N=N\c2c(cc(cc2[N+]([O-])=O)[N+]([O-])=O)C#N)c(NC(C)=O)c1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html.
53950-33-7	N-[2-[(2-bromo-4,6-dinitrophenyl)diazenyl]-5-(2-cyanoethylamino)-4-methoxyphenyl]acetamide	COc1cc(\N=N\c2c(Br)cc(cc2[N+]([O-])=O)[N+]([O-])=O)c(NC(C)=O)cc1NCCC#N	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html.
6379-46-0	2,3,4-trichloro-1,5-dinitrobenzene	[O-][N+](=O)c1cc(c(Cl)c(Cl)c1Cl)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html.
66557-45-7	N-[2-[(2-chloro-4,6-dinitrophenyl)diazenyl]-5-(diethylamino)phenyl]acetamide	CCN(CC)c1ccc(\N=N\c2c(Cl)cc(cc2[N+]([O-])=O)[N+]([O-])=O)c(NC(C)=O)c1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html.
78198-10-4	3,5-dinitrobenzoic acid 2-(methacryloyloxy)ethyl ester	CC(=C)C(=O)OCCOC(=O)c1cc(cc(c1)[N+]([O-])=O)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html.
79295-99-1	N-[2-[(2-chloro-4,6-dinitrophenyl)diazenyl]-5-(diethylamino)-4-methoxyphenyl]acetamide	CCN(CC)c1cc(NC(C)=O)c(cc1OC)\N=N\c1c(Cl)cc(cc1[N+]([O-])=O)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html.