CAS	Chem.name	Chem.SMILES	#Observed Mutagenicity	Bioassay - 	Reference(s) -
480-85-3	Retronecine	OCC1=CCN2CCC{P-}(O)C{P-}12	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Fu, P. P., Q. Xia, G. Lin, M. W. Chou, Pyrrolizidine Alkaloids - Genotoxicity, Metabolism Enzymes, Metabolic Activation, and Mechanisms, Drug Metabol. Rev. 36(1) (2004), 1-55
23107-12-2	Retronecine, 3,8-didehydro-	OCC1C=CN2CCC{P-}(O)C=12	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Robertson, K. A., Alkylation of N2 in Deoxyguanosine by Dehydroretronecine, Canc. Res. 42 (1982), 8-14; Reed, R. L., et. al., Crosslinking of DNA by Dehydroretronecine, a Metabolite of Pyrrolizidine Alkaloids, Carcinog. 9(8) (1988), 1355-1361
303-34-4	Lasiocarpine	CC=C(C)C(=O)OC1CCN2CC=C(COC(=O)C(O)(C(C)OC)C(C)(C)O)C12	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	P&G Inventory
480-81-9	Seneciphylline	CC=C1CC(=C)C(C)(O)C(=O)OCC2=CCN3CCC(C23)OC1=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	P&G Inventory
23246-96-0	Riddelliine	CC=C1CC(=C)C(O)(CO)C(=O)OCC2=CCN3CCC(C23)OC1=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Zeiger, E., et. al.; Salmonella Mutagenicity Tests: IV. Results From The Testing Of 300 Chemicals; Environ. Mol. Mutagen. 11(Suppl.12):1-158, 1988