CAS Chem.name Chem.SMILES #Observed Mutagenicity Bioassay - Reference(s) - 148-24-3 8-Hydroxyquinoline Oc1cccc2cccnc12 in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240; P&G Inventory 91-22-5 Quinoline c1ccc2ncccc2c1 in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240 107027-12-3 n-[2-(dimethylamino)ethyl]-2-phenyl-8-quinolinecarboxamide CN(C)CCNC(=O)c1cccc2ccc(nc21)-c1ccccc1 in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Denny, Wa., et. al.; Structure- Activity Relationships For The Mutagenic Activity Of Tricyclic Intercalating Agents In Salmonella Typhimurium; Mutat. Res. 232(2):233-241, 1990 56-57-5 4-Nitroquinoline-N-oxide [O-][N+](=O)c1cc[n+]([O-])c2ccccc12 in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240 4637-56-3 4-Hydroxyaminoquinoline-1-oxide ONc1cc[n+]([O-])c2ccccc12 in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240; Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25 54-05-7 Chloroquine CCN(CC)CCCC(C)Nc1ccnc2cc(Cl)ccc12 in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) CCRIS database,Toxnet databases: Shubber, Ek., Jacobson-Kram, D. And Williams, Jr.; Comparison Of The Ames Assay And The Induction Of Sister Chromatid Exchanges: Results With Ten Pharmaceuticals And Five Selected Agents; Cell Biol. Toxicol. 2(3):379-399, 1986 607-35-2 8-nitroquinoline;quinoline, 8-nitro- [O-][N+](=O)c1cccc2cccnc21 in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240 90-34-6 Primaquine;1,4-Pentanediamine, COc1cc(NC(C)CCCN)c2ncccc2c1 in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) CCRIS database,Toxnet databases; Chatterjee, T., A. Muhkopadhyay, K. A. Khan, A. K. Giri, Comparative Mutagenic and Genotoxic Effects of Three Antimalarial Drugs, Chloroquine, Primaquine and Amodiaquine, Mutagen. 13(6) (1998), 619 – 624 7471-63-8 7-methyl-8-nitroquinoline Cc1ccc2cccnc2c1[N+]([O-])=O in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html.