CAS	Chem.name	Chem.SMILES	#Observed Mutagenicity	Bioassay - 	Reference(s) -
1281189-85-2	3-Chloro-1-methyl-5-(trifluoromethyl)-2(1H)-pyridinone	CN1C=C(C(F)(F)F)C=C(Cl)C1=O	in vitro Ames negative	Bacterial Reverse Mutation Assay (e.g. Ames Test)	EFSA (2009) Public consultation on the active substance haloxyfop-P. https://www.efsa.europa.eu/en/consultations/call/public-consultation-active-substance-haloxyfop-p-0
1227574-71-1	3-Hydroxy-5-(trifluoromethyl)pyridin-2(1H)-one; HPDO;	OC1=CC(C(F)(F)F)=CNC1=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	US EPA (2009) Pyridalyl: Revised Human-Health Risk Assessment for Uses on Cotton, Fruiting Vegetables, Leafy Vegetables, Head & Stem Brassica Vegetables, Brassica Leafy Greens, and Turnip Greens, Shrubs, Ornamentals and Non-bearing Trees. https://www3.epa.gov/pesticides/chem_search/hhbp/R169200.pdf
76041-71-9	3-Chloro-2-hydroxy-5-(trifluoromethyl)pyridine	Oc1c(Cl)cc(C(F)(F)F)cn1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	EFSA (2009) Public consultation on the active substance haloxyfop-P; https://www.efsa.europa.eu/en/consultations/call/public-consultation-active-substance-haloxyfop-p-0;   21. Claxton L, K. Dearfield, R. Spanggord, E. Riccio, K. Mortelmans,  Mutat Res. 176(2) (1987) 1987, 185 – 198; http://dx.doi.org/10.1016/0027-5107(87)90049-2
33252-63-0	5-(Trifluoromethyl)-1H-pyridin-2-one;5-(trifluoromethyl)pyridin-2(1H)-one	O=C1C=CC(C(F)(F)F)=CN1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	European Food Safety Authority, Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl. EFSA J., 2013, 11(8), 3240 [87 pp.]. doi: 10.2903/j.efsa.2013.3240.   EFSA (2012) Public consultation on the active substance fluazifop-P. https://www.efsa.europa.eu/en/consultations/call/public-consultation-active-substance-fluazifop-p