CAS	Chem.name	Chem.SMILES	#Observed Mutagenicity	Bioassay - 	Reference(s) -
100-14-1	p-Nitrobenzyl chloride	[O-][N+](=O)c1ccc(CCl)cc1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
122-04-3	p-Nitrobenzoyl chloride	[O-][N+](=O)c1ccc(cc1)C(Cl)=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	P&G Inventory; Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
62-23-7	p-Nitrobenzoic acid	OC(=O)c1ccc(cc1)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	P&G Inventory; U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240
100-19-6	p-Nitroacetophenone	CC(=O)c1ccc(cc1)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	P&G Inventory; Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
100-27-6	p-Nitrophenethyl alcohol	OCCc1ccc(cc1)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	P&G Inventory; Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
2645-07-0	4-Nitrohippuric acid	OC(=O)CNC(=O)c1ccc(cc1)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	P&G Inventory; Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
139259-98-6	n-(acetyloxy)-n-[(4-nitrophenyl)methoxy]benzamide	CC(=O)ON(OCc1ccc(cc1)[N+]([O-])=O)C(=O)c1ccccc1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Bonin, Am., Banks, Tm., Campbell, Jj., Glover, Sa., Hammond, Gp., Prakash, As. and Rowbottom, Ca.; Mutagenicity Of Electrophilic N-Acyloxy-N-Alkoxyamides; Mutat. Res. 494(1-2):115-134, 2001
220168-55-8	n-[(4-nitrobenzoyl)oxy]-n-(phenylmethoxy)benzamide	[O-][N+](=O)c1ccc(cc1)C(=O)ON(OCc1ccccc1)C(=O)c1ccccc1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Bonin, Am., Banks, Tm., Campbell, Jj., Glover, Sa., Hammond, Gp., Prakash, As. and Rowbottom, Ca.; Mutagenicity Of Electrophilic N-Acyloxy-N-Alkoxyamides; Mutat. Res. 494(1-2):115-134, 2001
106268-95-5	(r)-glycidyl 4-nitrobenzoate	[O-][N+](=O)c1ccc(cc1)C(=O)OCC1CO1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	CCRIS database,Toxnet databases: Sinsheimer, Je, Chen, R, Das, Sk, Hooberman, Bh, Osorio, S And You, Z; The Genotoxicity Of Enantiomeric Aliphatic Epoxides; Mutat. Res. 298(3):197-206, 1993
2608-48-2	5-(4-Nitrophenyl)-2,4-pentadienal	[O-][N+](=O)c1ccc(C=CC=CC=O)cc1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Short-Term Test Program Sponsored By The Division Of Cancer Biology, National Cancer Institute, Ms. Ellen Zaika, Assistant Project Officer , p. Y86
*10005-63-2	N-[1-[3-[[(2R,3S)-3-[(R)-1-(trimethylsilyloxy)ethyl]-4-oxo-2-azetidinyl]methylcarbonylthio]-1-pyrrolidinyl]ethylidene]carbamic acid p-nitrobenzyl ester	C[C@@H](O[Si](C)(C)C)[C@H]1[C@H](CC(=O)SC2CCN(C2)C(/C)=N/C(=O)OCc2ccc(cc2)[N+]([O-])=O)NC1=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html.
10005-63-7	(5R,6S)-3-[[(3S)-1-[N-(p-nitrobenzyloxycarbonyl)acetimidoyl]-3-pyrrolidinyl]thio]-7-oxo-6-[(R)-1-(trimethylsilyloxy)ethyl]-1-azabicyclo[3.2.0]hepta-2-ene-2-carboxylic acid p-nitrobenzyl ester	C[C@@H](O[Si](C)(C)C)[C@H]1[C@@H]2CC(S[C@@H]3CCN(C3)C(/C)=N/C(=O)OCc3ccc(cc3)[N+]([O-])=O)=C(N2C1=O)C(=O)OCc1ccc(cc1)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html.
*10005-63-8	2-[(2S,3S)-2-[[[(3S)-1-[N-(p-nitrobenzyloxycarbonyl)acetimidoyl]-3-pyrrolidinyl]thio]carbonylmethyl]-4-oxo-3-[(R)-1-(trimethylsiloxy)ethyl]-2-azetidinyl]-2-oxoacetic acid p-nitrobenzyl ester	C[C@@H](O[Si](C)(C)C)[C@@H]1C(=O)N[C@@]1(CC(=O)S[C@@H]1CCN(C1)C(/C)=N/C(=O)OCc1ccc(cc1)[N+]([O-])=O)C(=O)C(=O)OCc1ccc(cc1)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html.
*10005-64-5	(5R,6S)-6-[(R)-1-hydroxyethyl]-3-[[(3S)-1-[N-(p-nitrobenzyloxycarbonyl)acetimidoyl]-3-pyrrolidinyl]thio]-7-oxo-1-azabicyclo[3.2.0]hepta-2-ene-2-carboxylic acid p-nitrobenzyl ester	C[C@@H](O)[C@H]1[C@@H]2CC(S[C@@H]3CCN(C3)C(/C)=N/C(=O)OCc3ccc(cc3)[N+]([O-])=O)=C(N2C1=O)C(=O)OCc1ccc(cc1)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html.
*10006-98-7	(4R)-4-[(2R,3S)-3-[(1R)-1-(tert-butyldimethylsilyloxy)ethyl]-4-oxo-2-azetidinyl]-2-diazo-3-oxovaleric acid p-nitrobenzyl ester	C[C@@H](O[Si](C)(C)C(C)(C)C)[C@H]1[C@H](NC1=O)[C@@H](C)C(=O)C(=[N+]=[N-])C(=O)OCc1ccc(cc1)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html.
*10010-17-9	(6R,7R)-7-amino-3-[(2S)-2-oxolanyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]octa-2-ene-2-carboxylic acid p-nitrobenzyl hydrochloride	Cl.N[C@H]1[C@H]2SCC([C@H]3CCCO3)=C(N2C1=O)C(=O)OCc1ccc(cc1)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html.
101803-29-6	(2S,4R)-4-hydroxy-2-(methoxycarbonyl)pyrrolidine-1-carboxylic acid 4-nitrobenzyl ester	COC(=O)[C@H]1C[C@@H](O)CN1C(=O)OCc1ccc(cc1)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html.
1037-31-6	4-nitrophenyl 4-nitrobenzoate	[O-][N+](=O)c1ccc(OC(=O)c2ccc(cc2)[N+]([O-])=O)cc1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html.
104773-40-2	(2S,4S)-4-(acetylthio)-2-(hydroxymethyl)pyrrolidine-1-carboxylic acid 4-nitrobenzyl ester	CC(=O)S[C@H]1C[C@@H](CO)N(C1)C(=O)OCc1ccc(cc1)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html.
127626-37-3	(4-nitrophenyl)methyl (2S,4R)-2-(hydroxymethyl)-4-methylsulfonyloxypyrrolidine-1-carboxylate	CS(=O)(=O)O[C@@H]1C[C@@H](CO)N(C1)C(=O)OCc1ccc(cc1)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html.
137391-68-5	(4R)-2-diazo-3-oxo-4-[(2R,3S)-4-oxo-3-[(1R)-1-hydroxyethyl]azetidine-2-yl]valeric acid 4-nitrobenzyl ester	C[C@@H](O)[C@H]1[C@H](NC1=O)[C@@H](C)C(=O)C(=[N+]=[N-])C(=O)OCc1ccc(cc1)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html.
138324-82-0	(2S,4R)-2-methyl 1-(4-nitrobenzyl) 4-((methylsulfonyl)oxy)pyrrolidine-1,2-dicarboxylate	COC(=O)[C@@H]1C[C@H](CN1C(=O)OCc1ccc(cc1)[N+]([O-])=O)OS(C)(=O)=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html.
148017-03-2	(2S,4S)-2-sulfamoylaminomethyl-4-mercaptopyrrolidine-1-carboxylic acid 4-nitrobenzyl ester	NS(=O)(=O)NC[C@H]1C[C@H](S)CN1C(=O)OCc1ccc(cc1)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html.
491878-06-9	(4-nitrophenyl)methyl (2S,4S)-4-acetylsulfanyl-2-[[(2-methylpropan-2-yl)oxycarbonyl-sulfamoylamino]methyl]pyrrolidine-1-carboxylate	CC(=O)S[C@H]1C[C@@H](CN(C(=O)OC(C)(C)C)S(N)(=O)=O)N(C1)C(=O)OCc1ccc(cc1)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html.
52648-77-8	1-(4-nitrophenyl)cyclopentane-1-carboxylic acid	OC(=O)C1(CCCC1)c1ccc(cc1)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html.
58816-66-3	3-(4-nitrophenyl)-L-alanine ethyl ester hydrochloride	Cl.CCOC(=O)[C@@H](N)Cc1ccc(cc1)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html.
61312-84-3	4-nitrobenzyl acetoacetate	CC(=O)CC(=O)OCc1ccc(cc1)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html.
67245-85-6	bis[(4-nitrophenyl)methyl] propanedioate	[O-][N+](=O)c1ccc(COC(=O)CC(=O)OCc2ccc(cc2)[N+]([O-])=O)cc1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html.
67821-33-4	4-nitrobenzoic acid 4-(2,2-dicyanoethenyl)phenyl ester	[O-][N+](=O)c1ccc(cc1)C(=O)Oc1ccc(cc1)C=C(C#N)C#N	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html.
74288-40-7	(4-nitrophenyl)methyl (5R,6S)-6-[(1R)-1-hydroxyethyl]-3,7-dioxo-1-azabicyclo[3.2.0]heptane-2-carboxylate	C[C@@H](O)[C@@H]1[C@H]2CC(=O)C(N2C1=O)C(=O)OCc1ccc(cc1)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html.
77359-11-6	4-nitrobenzyl hydrogen malonate	OC(=O)CC(=O)OCc1ccc(cc1)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html.
90505-34-3	[1-[(3R)-3-[(methylsulfonyl)oxy]pyrrolidine-1-yl]ethylidene]carbamic acid 4-nitrobenzyl ester	C\C(=N/C(=O)OCc1ccc(cc1)[N+]([O-])=O)N1CCCC1OS(C)(=O)=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html.
90505-36-5	[1-[(3S)-3-mercaptopyrrolidine-1-yl]ethylidene]carbamic acid 4-nitrobenzyl ester	C\C(=N/C(=O)OCc1ccc(cc1)[N+]([O-])=O)N1CC[C@H](S)C1	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html.
90822-22-3	(4R)-4-[(2R,3S)-3-[(1R)-1-(tert-butyldimethylsiloxy)ethyl]-4-oxoazetidine-2-yl]-3-oxovaleric acid 4-nitrobenzyl ester	C[C@@H](O[Si](C)(C)C(C)(C)C)[C@H]1[C@H](NC1=O)[C@@H](C)C(=O)CC(=O)OCc1ccc(cc1)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html.
90822-23-4	(4R)-4-[(2R,3S)-3-[(1R)-1-hydroxyethyl]-4-oxoazetidine-2-yl]-3-oxovaleric acid 4-nitrobenzyl ester	C[C@@H](O)[C@H]1[C@H](NC1=O)[C@@H](C)C(=O)CC(=O)OCc1ccc(cc1)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html.
96036-02-1	(4R,5S)-3-[[(3S)-1-(4-nitrobenzyloxycarbonyl)-5-(dimethylaminocarbonyl)pyrrolidine-3-yl]thio]-4a-methyl-6-[(1R)-1-hydroxyethyl]-7-oxo-1-azabicyclo[3.2.0]hepta-2-ene-2-carboxylic acid 4-nitrobenzyl ester	C[C@@H](O)[C@H]1[C@@H]2[C@@H](C)C(S[C@@H]3C[C@H](N(C3)C(=O)OCc3ccc(cc3)[N+]([O-])=O)C(=O)N(C)C)=C(N2C1=O)C(=O)OCc1ccc(cc1)[N+]([O-])=O	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html.
99-99-0	4-Nitrotoluene	Cc1ccc(cc1)[N+]([O-])=O	in vitro Ames negative	Bacterial Reverse Mutation Assay (e.g. Ames Test)	OECD, 4-Nitrotoluene, CAS No 99-99-0, SIDS Initial Assessment Report for SIAM 17 Arona, Italy, 11 - 14 November 2003