CAS Chem.name Chem.SMILES #Observed Mutagenicity Bioassay - Reference(s) - 109-64-8 1,3-Dibromopropane BrCCCBr in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) P&G Inventory 111-44-4 1-Chloro-2-(2-chloro-ethoxy)-ethane ClCCOCCCl in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) P&G Inventory 126-72-7 Tris(2,3-Dibromopropyl)Phosphate BrCC(Br)COP(=O)(OCC(Br)CBr)OCC(Br)CBr in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) P&G Inventory 627-30-5 3-Chloro-1-Propanol OCCCCl in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) P&G Inventory 2206-89-5 2-Chloroethyl Acrylate ClCCOC(=O)C=C in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) P&G Inventory 3066-70-4 2-Propenoic_acid,_2-methyl-,_2,3-dibromopropyl_ester CC(=C)C(=O)OCC(Br)CBr in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) P&G Inventory 13674-87-8 Tris(1,3-Dichloro-2-Propyl)Phosphate ClCC(CCl)OP(=O)(OC(CCl)CCl)OC(CCl)CCl in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) P&G Inventory; U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240 19660-16-3 2,3-Dibromopropyl crylate BrCC(Br)COC(=O)C=C in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) P&G Inventory 12789-03-6 chlordane ClC1CC2C(C1Cl)C1(Cl)C(Cl)=C(Cl)C2(Cl)C1(Cl)Cl in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Zeiger, E., et. al.; Salmonella Mutagenicity Tests. V. Results From The Testing Of 311 Chemicals; Environ. Mol. Mutagen. 19(SUPPL.21):2-141, 1992 78-87-5 1,2-Dichloro-propane CC(Cl)CCl in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240 302-17-0 Chloral hydrate OC(O)C(Cl)(Cl)Cl in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) P&G Inventory; U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240 106-93-4 1,2-Dibromaethane BrCCBr in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 127-00-4 1-Chloro-2-propanol CC(O)CCl in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) P&G Inventory; Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25 19686-73-8 1-Bromo-2-propanol CC(O)CBr in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) P&G Inventory; Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25 540-51-2 2-Bromo-1-ethanol OCCBr in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) P&G Inventory; U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240 554-10-9 3-Iodo-1,2-propanediol OCC(O)CI in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) P&G Inventory; Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25 616-23-9 2,3-Dichloropropan-1-ol OCC(Cl)CCl in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) P&G Inventory; Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25 627-18-9 3-Bromo-1-propanol OCCCBr in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) P&G Inventory; Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25 74-96-4 Ethyl bromide CCBr in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) P&G Inventory; Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25 96-13-9 2,3-Dibromo-1-propanol OCC(Br)CBr in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) P&G Inventory; Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25 96-23-1 1,3-Dichloro-2-propanol OC(CCl)CCl in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) P&G Inventory; Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25 75-26-3 2-Bromopropane CC(C)Br in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) P&G Inventory; Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25 75-00-3 Ethyl chloride CCCl in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory *6-00-9 ICR 442 COc1ccc2nc3ccccc3c(NCCNCC(C)Cl)c2c1 in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) DeMarini D.M.,et.al, Relationships between structures and mutagenic potencies of 16 heterocyclic nitrogen mustards (ICR compounds) in Salmonella typhimurium Mut.Research, 136 (1984) 185-199 *6-01-3 ICR 443 COc1ccc2nc3cc(Cl)ccc3c(NCCNCC(C)Cl)c2c1 in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) DeMarini D.M.,et.al, Relationships between structures and mutagenic potencies of 16 heterocyclic nitrogen mustards (ICR compounds) in Salmonella typhimurium Mut.Research, 136 (1984) 185-199 112-26-5 1,2-Bis(2-chloroethoxy)ethane ClCCOCCOCCCl in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) NIHS Japan 109-70-6 1-bromo-3-chloropropane ClCCCBr in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) NIHS Japan 75-87-6 Trichloroacetaldehyde ClC(Cl)(Cl)C=O in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Waskell, L.; A Study Of The Mutagenicity Of Anesthetics And Their Metabolites; Mutat. Res. 57:141-153, 1978 107-07-3 2-Chloroethanol OCCCl in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Toxicology and Carcinogenesis Studies of 2-Chloroethanol (Ethylene Chlorohydrin) (CAS No. 107-07-3) in F344/N Rats and Swiss CD-1 Mice (Dermal Studies), US Dept. of Health and Human Services, Public health Service, NIH, November 1985 488-41-5 Mitobronitol O[C@@H](CBr)[C@H](O)[C@@H](O)[C@@H](O)CBr in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) P&G Inventory; Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25 107-06-2 1,2-Dichloro-ethane ClCCCl in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Brem, H, et al; Cancer Res. 34:2576-2579, 1974; Strobel, K And Grummt, T; Toxicol. Environ. Chem. 15(1-2):101-128, 1987 4823-47-6 Acrylic acid, 2-bromoethyl ester BrCCOC(=O)C=C in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Zeiger, E, Anderson ,B, Haworth, S, Lawlor, T, Mortelmans, K And Speck, W; Salmonella Mutagenicity Tests: III. Results From The Testing Of 255 Chemicals; Environ. Mol. Mutagen. 9(Suppl.9):1-110, 1987 106-94-5 1-bromopropane CCCBr in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) E.D. Barber, W.H. Donish, K.R. Mueller, A procedure for the quantitative measurement of the mutagenicity of volatile liquids in the Ames salmonella/microsome assay, Mutat Res 90 (1) (1981) 31-48. 10318-26-0 dibromodulcitol; mitolactol OC(CBr)C(O)C(O)C(O)CBr in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) CCRIS database,Toxnet databases: Mortelmans, K., Haworth, S., Lawlor, T., Speck, W., Tainer, B. And Zeiger, E.; Salmonella Mutagenicity Tests: Ii. Results From The Testing Of 270 Chemicals; Environ. Mutagen. 8(Suppl. 7):1-119, 1986 106-89-8 epichlorohydrin; oxirane, 2-(chloromethyl)- ClCC1CO1 in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) CCRIS database,Toxnet databases: Brams, A., et. al.; A Comparative Study, With 40 Chemicals, Of The Efficiency Of The Salmonella Assay And The SOS Chromotest (Kit Procedure); Toxicol. Lett. 38(1-2):123-133, 1987 5634-39-9 iodinated glycerol;2-(1-iodoethyl)-1,3-dioxolan-4-ylmethanol; CC(I)C1OCC(CO)O1 in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) CCRIS database,Toxnet databases: NCI/NTP carcinogens technical report series; National Cancer Institute/National Toxicology Program; U.S. Department Of Health And Human Services, Tr-340 Y90; Zeiger,E, Anderson,B, Haworth,S, Lawlor,T, Mortelmans,K And Speck,W; Salmonella Mutagenicity Tests: III. Results From The Testing Of 255 Chemicals; Environ. Mol. Mutagen. 9(Suppl.9):1-110, 1987 71-55-6 methylchloroform CC(Cl)(Cl)Cl in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) CCRIS database,Toxnet databases: Strubel, K., T. Grummt, Aliphatic and Aromatic Halocarbons as Potential Mutagens in Drinking Water. III. Halogenated Ethanes and Ethenes, Toxicol. Environ. Chem. 15(1-2) (1987), 101 – 128 *10002-20-2 1,1-bis[p-(3-chloro-2-hydroxypropoxy)phenyl]ethane CC(c1ccc(OCC(O)CCl)cc1)c1ccc(OCC(O)CCl)cc1 in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html. *10005-94-2 2-chloro-2-(2-chlorophenyl)ethanol OCC(Cl)c1ccccc1Cl in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html. *10008-40-8 2-nitrobenzenesulfonic acid 4-chlorobutyl ester [O-][N+](=O)c1ccccc1S(=O)(=O)OCCCCCl in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html. *10009-61-2 2-chloro-3-isobutoxy-1-cyclobutanone CC(C)COC1CC(=O)C1Cl in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html. 128668-81-5 6-(3-chloro-2-hydroxypropoxy)-1,2-dihydroquinoline-2-one OC(CCl)COc1ccc2NC(=O)C=Cc2c1 in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html. 137-43-9 bromocyclopentane BrC1CCCC1 in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html. 154325-75-4 5-bromo-2,2-dimethyl-4-oxopentanoic acid ethyl ester CCOC(=O)C(C)(C)CC(=O)CBr in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html. 1768-31-6 1,1,1,3,3-pentachloroacetone ClC(Cl)C(=O)C(Cl)(Cl)Cl in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html. 20133-93-1 1-chloro-3-(1-naphthoxy)-2-propanol OC(CCl)COc1cccc2ccccc12 in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html. 20163-90-0 2,3-dibromo-1,4-butanediol OCC(Br)C(Br)CO in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html. 3967-54-2 4-chloro-1,3-dioxolan-2-one ClC1COC(=O)O1 in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html. 832151-99-2 2,2-dimethylpropanoic acid (1R)-3-chloro-1-methyl-2-oxopropyl ester C[C@@H](OC(=O)C(C)(C)C)C(=O)CCl in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html. 888494-24-4 glycine, N-[(2R)-2-chloropropyl]-N-(phenylmethyl)-,1,1-dimethylethyl ester C[C@@H](Cl)CN(CC(=O)OC(C)(C)C)Cc1ccccc1 in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html. 76-44-8 Heptachlor ClC1C=CC2C1C1(Cl)C(Cl)=C(Cl)C2(Cl)C1(Cl)Cl in vitro Ames negative Bacterial Reverse Mutation Assay (e.g. Ames Test) U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240; P&G Inventory; CCRIS database,Toxnet databases 109-69-3 N-Butyl chloride CCCCCl in vitro Ames negative Bacterial Reverse Mutation Assay (e.g. Ames Test) P&G Inventory; Japan Existing Chemical Data Base; http://dra4.nihs.go.jp/mhlw_data/jsp/SearchPageENG.jsp 79-00-5 1,1,2-Trichloroethane ClCC(Cl)Cl in vitro Ames negative Bacterial Reverse Mutation Assay (e.g. Ames Test) Strobel, K And Grummt, T; Aliphatic And Aromatic Halocarbons As Potential Mutagens In Drinking Water. Iii. Halogenated Ethanes And Ethenes; Toxicol. Environ. Chem. 15(1-2):101-128, 1987 81112-08-5 N-[4-(2-chloropropanoyl)phenyl]acetamide CC(Cl)C(=O)c1ccc(NC(C)=O)cc1 in vitro Ames negative Bacterial Reverse Mutation Assay (e.g. Ames Test) Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html. Last visited:October, 2021. *10019-08-3 N-[4-(2-chloropropanoyl)-2-nitrophenyl]acetamide CC(Cl)C(=O)c1ccc(NC(C)=O)c(N(=O)=O)c1 in vitro Ames negative Bacterial Reverse Mutation Assay (e.g. Ames Test) Division of Genetic and Mutagenesis, National Institute of Health Science, Japan. ANEI-HOU, AMES/ QSAR International Collaborative Study; http://www.nihs.go.jp/dgm/amesqsar.html. Last visited:October, 2021.