CAS	Chem.name	Chem.SMILES	#Observed Mutagenicity without S9	#Observed Mutagenicity with S9	Bioassay - 	Reference(s) -
50-29-3	4,4'-Dichlorodiphenyltrichloroethane; p,p'-DDT	Clc1ccc(C(c2ccc(Cl)cc2)C(Cl)(Cl)Cl)cc1	in vitro Ames negative	in vitro Ames negative	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
53-19-0	o,p'-DDD; o,p'-Dichlorodiphenyldichloroethane	ClC(Cl)C(c1ccccc1Cl)c1ccc(Cl)cc1	in vitro Ames negative	in vitro Ames negative	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
67-72-1	Hexachloroethane	ClC(Cl)(Cl)C(Cl)(Cl)Cl	in vitro Ames negative	in vitro Ames negative	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
72-43-5	1,1,1-Trichloro-2,2'-bis(4-methoxyphenyl)ethane; Methoxychlor	COc1ccc(C(c2ccc(OC)cc2)C(Cl)(Cl)Cl)cc1	in vitro Ames negative	in vitro Ames negative	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
72-54-8	Tetrachlorodiphenylethane	ClC(Cl)C(c1ccc(Cl)cc1)c1ccc(Cl)cc1	in vitro Ames negative	in vitro Ames negative	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
75-34-3	1,1-Dichloroethane	CC(Cl)Cl	in vitro Ames negative	in vitro Ames negative	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
75-36-5	Acetyl chloride	CC(=O)Cl	in vitro Ames negative	in vitro Ames negative	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
76-01-7	Pentachloroethane	ClC(Cl)C(Cl)(Cl)Cl	in vitro Ames negative	in vitro Ames negative	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
115-32-2	2,2,2-Trichloro-1,1-bis(4-chlorophenyl)ethanol	OC(c1ccc(Cl)cc1)(c1ccc(Cl)cc1)C(Cl)(Cl)Cl	in vitro Ames negative	in vitro Ames negative	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
151-67-7	Halothane	FC(F)(F)C(Cl)Br	in vitro Ames negative	in vitro Ames negative	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
79-27-6	1,1,2,2-Tetrabromoethane	BrC(Br)C(Br)Br	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Strubel, K., T. Grummt, Aliphatic and Aromatic Halocarbons as Potential Mutagens in Drinking Water. III. Halogenated Ethanes and Ethenes, Toxicol. Environ. Chem. 15(1-2) (1987), 101 – 128
982-57-0	Chloramphenicol sodium succinate	[Na+].OC(C(COC(=O)CCC([O-])=O)NC(=O)C(Cl)Cl)c1ccc(cc1)[N+]([O-])=O	in vitro Ames negative	in vitro Ames negative	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
76-38-0	Methoxyflurane	COC(F)(F)C(Cl)Cl	in vitro Ames negative	in vitro Ames negative	Bacterial Reverse Mutation Assay (e.g. Ames Test)	ZEIGER,E, ANDERSON,B, HAWORTH,S, LAWLOR,T AND MORTELMANS,K; ENVIRON. MOL. MUTAGEN. 19(SUPPL.21):2-141, 1992
156-59-2	cis-1,2-Dichloroethylene	Cl/C=C\Cl	in vitro Ames negative	in vitro Ames negative	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
540-59-0	1,2-Dichloroethylene	Cl\C=C\Cl	in vitro Ames negative	in vitro Ames negative	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
141-75-3	Butyryl chloride	CCCC(=O)Cl	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
100-14-1	p-Nitrobenzyl Chloride	[O-][N+](=O)C1=CC=C(CCl)C=C1	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
100-39-0	alpha-Bromotoluene	BrCc1ccccc1	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
121-90-4	m-Nitrobenzoyl Chloride	[O-][N+](=O)c1cccc(c1)C(Cl)=O	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
122-04-3	p-Nitrobenzoyl Chloride	[O-][N+](=O)c1ccc(cc1)C(Cl)=O	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
52-68-6	Trichlorfon	COP(=O)(C(O)C(Cl)(Cl)Cl)OC	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
6959-47-3	2-(Chloromethyl)Pyridine Hydrohloride	ClCc1ccccn1	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
6959-48-4	3-(Chloromethyl)Pyridine.HCl	ClCc1cccnc1	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
16238-56-5	7-Bromomethyl-12-Methylbenz(A)Anthracene	Cc1c2ccccc2c(CBr)c2ccc3ccccc3c12	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
612-23-7	o-Nitrobenzyl Chloride	c1(ccccc1CCl)[N+](=O)[O-]	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
619-23-8	m-Nitrobenzyl Chloride	c1(cccc(CCl)c1)[N+](=O)[O-]	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
62-73-7	Dichlorvos	COP(=O)(OC)OC=C(Cl)Cl	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	U.S.Environmental Protection Agency Gene-Tox Program. Mutation Research, 168, (1996) pp. 69-240
79-36-7	Acetyl chloride	O=C(Cl)C(Cl)Cl	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
98-07-7	Benzotrichloride	ClC(Cl)(Cl)c1ccccc1	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
98-87-3	Alpha,Alpha-Dichlorotoluene	ClC(Cl)c1ccccc1	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
393-52-2	2-Fluorobenzoyl Chloride	O=C(Cl)c1ccccc1F	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
611-19-8	Benzene,1-chloro-2-(chloromethyl)-	ClCc1ccccc1Cl	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	NIHS Japan
100-44-7	Benzyl chloride	ClCc1ccccc1	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
115453-72-0	s-(1,2,3,3,3-pentachloroprop-1-enyl)-l-cysteine	NC(CSC(Cl)=C(Cl)C(Cl)(Cl)Cl)C(O)=O	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	VAMVAKAS,S, BERTHOLD,K, DEKANT,W AND HENSCHLER,D; CHEM.BIOL. INTERACT. 65(1):5971, 1988
97055-38-4	3-chloro-4-(dichloromethyl)-5-methoxy-2(5h)-furanone	COC1C(C(Cl)Cl)=C(Cl)C(=O)O1	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
122551-89-7	3-chloro-4-(dichloromethyl)-2(5h)-furanone;3-chloro-4-(dichloromethyl)-2-(5h)-furanone	O=C1C(Cl)=C(C(Cl)Cl)CO1	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	LALONDE,RT, COOK,GP, PERAKYLA,H, DENCE,CW AND BABISH,JG; ENVIRON. MOL. MUTAGEN. 17(1):4048, 1991; KRONBERG,L, CHRISTMAN,RF, SINGH,R, AND BALL,LM; ENVIRON. SCI. TECHNOL. 25(1):99104, 1991
132059-51-9	3-chloro-4-(bromochloromethyl)-5-hydroxy-2(5h)-furanone	OC1C(C(Cl)Br)=C(Cl)C(=O)O1	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	SUZUKI,N AND MATSUO,T; J. FAC. ENG. UNIV. TOKYO, SER.B 42(4):307315, 1994; RAMOS,I LLOVERAS,M SOLANS,X HUICI,A AND MESSEGUER,A; ENVIRON. TOXICOL. CHEM. 19(11):26312636, 2000; RAMOS,I LLOVERAS,M SOLANS,X HUICI,A AND MESSEGUER,A; ENVIRON. TOXICOL. CHEM. 19(11):26312636, 2000
132059-52-0	3-chloro-4-(dibromomethyl)-5-hydroxy-2(5h)-furanone	OC1C(C(Br)Br)=C(Cl)C(=O)O1	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	SUZUKI,N AND MATSUO,T; J. FAC. ENG. UNIV. TOKYO, SER.B 42(4):307315, 1994; LALONDE,RT, BU,L, HENWOOD,A, FIUMANO,J AND ZHANG,L;CHEM. RES. TOXICOL. 10(12):14271436, 1997; RAMOS,I LLOVERAS,M SOLANS,X HUICI,A AND MESSEGUER,A; ENVIRON. TOXICOL. CHEM. 19(11):26312636, 2000
132059-53-1	3-bromo-4-(dibromomethyl)-5-hydroxy-2(5h)-furanone	OC1C(C(Br)Br)=C(Br)C(=O)O1	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	SUZUKI,N AND MATSUO,T; J. FAC. ENG. UNIV. TOKYO, SER.B 42(4):307315, 1994; LALONDE,RT, BU,L, HENWOOD,A, FIUMANO,J AND ZHANG,L;CHEM. RES. TOXICOL. 10(12):14271436, 1997; RAMOS,I LLOVERAS,M SOLANS,X HUICI,A AND MESSEGUER,A; ENVIRON. TOXICOL. CHEM. 19(11):26312636, 2000
199536-79-3	3-bromo-4-(dibromomethyl)-2(5h)-furanone	O=C1C(Br)=C(C(Br)Br)CO1	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	LALONDE,RT, BU,L, HENWOOD,A, FIUMANO,J AND ZHANG,L; CHEM. RES. TOXICOL. 10(12):14271436, 1997
199536-82-8	3-chloro-4-(dibromomethyl)-2(5h)-furanone	O=C1C(Cl)=C(C(Br)Br)CO1	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	LALONDE,RT, BU,L, HENWOOD,A, FIUMANO,J AND ZHANG,L; CHEM. RES. TOXICOL. 10(12):14271436, 1997
79-00-5	1,1,2-Trichloroethane	ClCC(Cl)Cl	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	STROBEL,K AND GRUMMT,T; ALIPHATIC AND AROMATIC HALOCARBONS AS POTENTIAL MUTAGENS IN DRINKING WATER. III. HALOGENATED ETHANES AND ETHENES; TOXICOL. ENVIRON. CHEM. 15(1-2):101-128, 1987;
79-01-6	Trichloroethylene	ClC=C(Cl)Cl	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	STROBEL,K AND GRUMMT,T; ALIPHATIC AND AROMATIC HALOCARBONS AS POTENTIAL MUTAGENS IN DRINKING WATER. III. HALOGENATED ETHANES AND ETHENES; TOXICOL. ENVIRON. CHEM. 15(1-2):101-128, 1987
72-56-0	Di(P-Ethylphenyl)dichloroethane	CCc1ccc(C(C(Cl)Cl)c2ccc(CC)cc2)cc1	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
594-72-9	1,1-Dichloro-1-Nitroethane	CC(Cl)(Cl)[N+](=O)[O-]	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
1929-82-4	2-Chloro-6-(Trichloromethyl)Pyridine	Clc1cccc(C(Cl)(Cl)Cl)n1	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
5216-25-1	4-Chlorobenzotrichloride	Clc1ccc(C(Cl)(Cl)Cl)cc1	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
13014-18-1	2,4-Dichlorophenyltrichloromethane	Clc1ccc(C(Cl)(Cl)Cl)c(Cl)c1	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
13014-24-9	3,4-Dichlorophenyltrichloromethane	Clc1ccc(C(Cl)(Cl)Cl)cc1Cl	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
75-35-4	1,1-Dichloroethylene	C=C(Cl)Cl	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	STROBEL,K AND GRUMMT,T; ALIPHATIC AND AROMATIC HALOCARBONS AS POTENTIAL MUTAGENS IN DRINKING WATER. III. HALOGENATED ETHANES AND ETHENES; TOXICOL. ENVIRON. CHEM. 15(1-2):101-128, 1987; GOTO,S, SHIRAISHI,F, TANABE,K, ENDO,O, MACHII,K, TEZUKA,Y, ISHII,T AND MATSUSHITA,H; MUTAGENICITY DETECTION METHOD FOR VINYL CHLORIDE AND VINYLIDENE CHLORIDE GASES; KANKYO KAGAKU 5(2):235-240, 1995
127-18-4	Tetrachloroethylene	ClC(Cl)=C(Cl)Cl	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	VAMVAKAS,S, et. al.; MUTAGENICITY OF TETRACHLOROETHENE IN THE AMES TEST-METABOLIC ACTIVATION BY CONJUGATION WITH GLUTATHIONE; J. BIOCHEM. TOXICOL. 4(1):21-27, 1989; SHIMADA,T,  et. al.; ACTIVITIES OF CHLORINATED ETHANE AND ETHYLENE COMPOUNDS IN THE SALMONELLA/RAT MICROSOME MUTAGENESIS AND RAT HEPATOCYTE/DNA REPAIR ASSAYS UNDER VAPOR PHASE EXPOSURE CONDITIONS; CELL BIOL. TOXICOL. 1(3):159-179, 1985
5589-96-8	bromochloroacetic acid	OC(=O)C(Cl)Br	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	MORITA,H, TADAKI,S, NOZAKA,T, OMURA,T, HAGA,M AND TANAKA,A; MUTAGENICITY AND CONCENTRATION OF CHLORINATION BYPRODUCTS IN TAP WATER IN SAITAMA; KANKYO HEN'IGEN KENKYU 19(3):127-134, 1997
6/1/2425	Captafol	O=C1C2CC=CCC2C(=O)N1SC(Cl)(Cl)C(Cl)Cl	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Barrueco, C. and De La Pena, E.; Mutagenic Evaluation of the Pesticides Captan, Folpet, Captafol, Dichlofluanid and Related Compounds with the Mutants TA 102 and TA 104 of Salmonella Typhimurium; Mutagenesis 3(6):467-480, 1988
1086-00-6	1-Chloromethylpyrene	ClCc1ccc2ccc3cccc4ccc1c2c34	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Ashby, J., Gallagher, Je., Kohan, M., Tinwell, H., Kimber, I., Paton, D., Callander, Rd. and Chouroulinkov, I.; 1-Chloromethylpyrene: A Reference Skin Sensitizer And Genotoxin; Mutat. Res. 243(4):281-9, 1990
631-64-1	Dibromoacetic acid	OC(=O)C(Br)Br	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	SAITO,H, ISODA,S, KATO,M AND NAGAOKA,N; MUTAGENIC ACTIVITY OF INDOOR SWIMMING POOL WATER; KANKYO HENIGEN KENKYU 17(2):169-177, 1995
79-43-6	Dichloracetic acid; Acetic acid, 2,2-dichloro-	OC(=O)C(Cl)Cl	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Demarini, Dm., Perry, E. And Shelton, Ml.; Dichloroacetic Acid And Related Compounds: Induction Of Prophage In E. Coli And Mutagenicity And Mutation Spectra In Salmonella TA100; Mutagenesis 9(5):429-437, 1994
71-55-6	Methylchloroform	CC(Cl)(Cl)Cl	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Strubel, K., T. Grummt, Aliphatic and Aromatic Halocarbons as Potential Mutagens in Drinking Water. III. Halogenated Ethanes and Ethenes, Toxicol. Environ. Chem. 15(1-2) (1987), 101 – 128