CAS	Chem.name	Chem.SMILES	#Observed Mutagenicity without S9	#Observed Mutagenicity with S9	Bioassay - 	Reference(s) -
57-71-6	2,3-Butanedione 2-oxime	CC(=O)C(C)=NO	in vitro Ames negative	in vitro Ames negative	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
136-77-6	4-Hexylresorcinol	CCCCCCc1ccc(O)cc1O	in vitro Ames negative	in vitro Ames negative	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
609-31-4	2-nitro-1-butanol	CCC(CO)[N+]([O-])=O	in vitro Ames negative	in vitro Ames negative	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
513-86-0	Acetoin	CC(O)C(C)=O	in vitro Ames negative	in vitro Ames negative	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
80-71-7	Methylcyclo- pentenolone	CC1CCC(=O)C=1O	in vitro Ames negative	in vitro Ames negative	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
10316-66-2	2-Hydroxy-2-cyclohexen-1-one	OC1=CCCCC1=O	in vitro Ames negative	in vitro Ames negative	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Dorado L., et al Mutation Res., v.269, pp. 301-306 (1992)
156324-78-6	l-Menthol ethylene glycol carbonate	CC(C)C{P+}1CCC{P-}(C)CC{P-}1OC(=O)OCCO	in vitro Ames negative	in vitro Ames negative	Bacterial Reverse Mutation Assay (e.g. Ames Test)	World Health Organization, Geneva, 1999
63-56-9	Thonzylamine hydrochloride	Cl_CN(C)CCN(Cc1ccc(OC)cc1)c1ncccn1	in vitro Ames negative	in vitro Ames negative	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
24382-04-5	3-Hydroxy-2-Propenal Sodium Salt	O=CC{-}(.[Na]{+})C=O	in vitro Ames negative	in vitro Ames negative	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
110-49-6	2-Methoxyethyl Acetate	CC(=O)OCCOC	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
111-30-8	Glutaraldehyde	O=CCCCC=O	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
3658-77-3	3(2h)-Furanone,2,5-Dimethyl-4-Hydroxy-	CC1C(=O)C(O)=C(C)O1	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
81-54-9	1,2,4-Trihydroxyanthraquinone	Oc1cc(O)c(O)c2c1C(=O)c1ccccc1C2=O	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
50-81-7	Vitamin C	OCC(O)C1C(O)=C(O)C(=O)O1	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
78-98-8	Pyruvaldehyde	CC(=O)C=O	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
107-22-2	Glyoxal	O=CC=O	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
431-03-8	2,3-butanedione	CC(=O)C(C)=O	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
765-87-7	1,2-Cyclohexanedione	O=C1CCCCC1=O	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
53-03-2	Prednisone	CC12CC(=O)C3C(CCC4=CC(=O)C=CC34C)C1CCC2(O)C(=O)CO	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
1192-62-7	2-Furyl methyl ketone; 2-Acetylfuran	CC(=O)C1=CC=CO1	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	SHINOHARA,K, KIM, EH AND OMURA,H; FURANS AS THE MUTAGENS FORMED BY AMINO-CARBONYL REACTIONS; DEV. FOOD SCI. 13(AMINO-CARBONYL REACT. FOOD BIOL. SYST.):353-362, 1986
108-46-3	Resorcinol	Oc1cccc(O)c1	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	HOSONO,A, MAKINO,K AND OTANI,H; MUTAGENICITY OF RESORCINOL FORMED BY THE REACTION OF M-PHENYLENEDIAMINE WITH SODIUM NITRITE; J. AGRIC. FOOD CHEM. 39(10):1817-1819, 1991
485-47-2	Ninhydrin	OC1(O)C(=O)c2ccccc2C1=O	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	ZEIGER,E,  et. al.; SALMONELLA MUTAGENICITY TESTS: III. RESULTS FROM THE TESTING OF 255 CHEMICALS; ENVIRON. MOL. MUTAGEN. 9(SUPPL.9):1-110, 1987
505-22-6	1,3-Dioxane	C1CCOCO1	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	HAWORTH,S, LAWLOR,T MORTELMANS,K, SPECK,W AND ZEIGER,E; SALMONELLA MUTAGENICITY TEST RESULTS FOR 250 CHEMICALS; ENVIRON. MUTAGEN. 5(SUPPL. 1): 3-142, 1983
518-82-1	Emodin	Cc1cc(O)c2c(c1)C(=O)c1cc(O)cc(O)c1C2=O	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	WESTENDORF,J, MARQUARDT,H, POGINSKY,B, DOMINIAK,M, SCHMIDT,J AND MARQUARDT,H; GENOTOXICITY OF NATURALLY OCCURRING HYDROXYANTHRAQUINONES; MUTAT. RES. 240(1): 1-12, 1990
501-30-4	Kojic acid; 5-hydroxy-2-hydroxymethyl-pyran-4-one	OCC1=CC(=O)C(O)=CO1	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	WEI,CI, HUANG,TS, FERNANDO,SY AND CHUNG,KT;MUTAGENICITY STUDIES OF KOJIC ACID; TOXICOL. LETT. 59(1-3):213-220, 1991
542-78-9	Malondialdehyde; 3-hydroxy-2-propenal sodium salt	O=CCC=O	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	MARNETT,LJ, HURD,HK, HOLLSTEIN,MC, LEVIN,DE, ESTERBAUER,H AND AMES,BN; NATURALLY OCCURRING CARBONYL COMPOUNDS ARE MUTAGENS IN SALMONELLA TESTER STRAIN TA104;MUTAT. RES. 148(1-2):25-34, 1985
118-71-8	3-hydroxy-2-methyl-4-pyrone;maltol	CC1=C(O)C(=O)C=CO1	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	D. Kirkland, L. Reeve, D. Gatehouse, P. Vanparys, A core in vitro genotoxicity battery comprising the Ames test plus the in vitro micronucleus test is sufficient to detect rodent carcinogens and in vivo genotoxins, Mutat. Res. 721 (2011) 27-73.
533-73-3	1,2,4-trihydroxybenzene; 1,2,4-benzenetriol	Oc1ccc(O)cc1O	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Lin,JK and Lee,SF; ENHANCEMENT OF THE MUTAGENICITY OF POLYPHENOLS BY CHLORINATION AND NITROSATION IN SALMONELLA TYPHIMURIUM; MUTAT. RES. 269(2): 217-224, 1992