CAS	Chem.name	Chem.SMILES	#Observed Mutagenicity without S9	#Observed Mutagenicity with S9	Bioassay - 	Reference(s) -
126-99-8	2-Cloro-1,3-butadiene; Chloroprene	C=CC(=C)Cl	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	http://apps.echa.europa.eu/registered/data/dossiers/DISS-9d846852-dfce-5fff-e044-00144f67d249/AGGR-cee6a0b3-a1ad-4967-b7b0-e6b0d95ea22a_DISS-9d846852-dfce-5fff-e044-00144f67d249.html#AGGR-cee6a0b3-a1ad-4967-b7b0-e6b0d95ea22a
79-27-6	1,1,2,2-Tetrabromoethane	BrC(Br)C(Br)Br	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Strubel, K., T. Grummt, Aliphatic and Aromatic Halocarbons as Potential Mutagens in Drinking Water. III. Halogenated Ethanes and Ethenes, Toxicol. Environ. Chem. 15(1-2) (1987), 101 – 128
62-73-7	Dichlorvos	COP(=O)(OC)OC=C(Cl)Cl	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	U.S.Environmental Protection Agency Gene-Tox Program. Mutation Research, 168, (1996) pp. 69-240
78-88-6	2,3-Dichloro-1-Propene	C=C(Cl)CCl	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	U.S.Environmental Protection Agency Gene-Tox Program. Mutation Research, 168, (1996) pp. 69-240
7166-19-0	Beta-Bromo-Beta-Nitrostyrene	[O-][N+](=O)C(Br)=Cc1ccccc1	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
87619-82-7	s-(1,2,3,4,4-pentachloro-1,3-butadienyl)-l-cysteine	NC(CSC(Cl)=C(Cl)C(Cl)=C(Cl)Cl)C(O)=O	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
98025-31-1	s-(1,2,2-trichlorovinyl)-l-cysteine	NC(CSC(Cl)=C(Cl)Cl)C(O)=O	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
111348-61-9	s-trichlorovinyl-n-acetylcysteine	CC(=O)NC(CSC(Cl)=C(Cl)Cl)C(O)=O	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	VAMVAKAS,S, DEKANT,W, BERTHOLD,K, SCHMIDT,S, WILD,D AND HENSCHLER,D; BIOCHEM. PHARMACOL. 36(17):27412748, 1987
766-40-5	3,4-dichloro-5-hydroxy-2(5h)-furanone;3,4-dichloro-5-hydroxyfuran-2(5h)-one	OC1C(Cl)=C(Cl)C(=O)O1	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
31555-54-1	3,4-dichloro-5-dichloromethylene-2-furanone	O=C1C(Cl)=C(Cl)C(=C(Cl)Cl)O1	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
112654-68-9	3-chloro-5-dichloromethylene-2-furanone	O=C1C(Cl)=CC(=C(Cl)Cl)O1	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	SMEDS,A, FRANZEN,R AND KRONBERG,L; ENVIRON. SCI. TECHNOL. 29(9):18391844, 1995
149418-41-7	3,4-dibromo-2(5h)-furanone	O=C1C(Br)=C(Br)CO1	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	LALONDE,RT AND LEO,HR; CHEM. RES. TOXICOL. 7(6):779783, 1994
630-20-6	1,1,1,2-Tetrachloroethane	ClCC(Cl)(Cl)Cl	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	STROBEL,K AND GRUMMT,T; ALIPHATIC AND AROMATIC HALOCARBONS AS POTENTIAL MUTAGENS IN DRINKING WATER. III. HALOGENATED ETHANES AND ETHENES; TOXICOL. ENVIRON. CHEM. 15(1-2):101-128, 1987
79-01-6	Trichloroethylene	ClC=C(Cl)Cl	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	STROBEL,K AND GRUMMT,T; ALIPHATIC AND AROMATIC HALOCARBONS AS POTENTIAL MUTAGENS IN DRINKING WATER. III. HALOGENATED ETHANES AND ETHENES; TOXICOL. ENVIRON. CHEM. 15(1-2):101-128, 1987
87-68-3	Hexachloro-1,3-butadiene	ClC(Cl)=C(Cl)C(Cl)=C(Cl)Cl	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
3234-02-4	Trans-2,3-Dibromo-2-Butene-1,4-Diol	OCC(Br)=C(Br)CO	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
75-35-4	1,1-Dichloroethylene	C=C(Cl)Cl	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	STROBEL,K AND GRUMMT,T; ALIPHATIC AND AROMATIC HALOCARBONS AS POTENTIAL MUTAGENS IN DRINKING WATER. III. HALOGENATED ETHANES AND ETHENES; TOXICOL. ENVIRON. CHEM. 15(1-2):101-128, 1987; GOTO,S, SHIRAISHI,F, TANABE,K, ENDO,O, MACHII,K, TEZUKA,Y, ISHII,T AND MATSUSHITA,H; MUTAGENICITY DETECTION METHOD FOR VINYL CHLORIDE AND VINYLIDENE CHLORIDE GASES; KANKYO KAGAKU 5(2):235-240, 1995
127-18-4	Tetrachloroethylene	ClC(Cl)=C(Cl)Cl	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	VAMVAKAS,S, et. al.; MUTAGENICITY OF TETRACHLOROETHENE IN THE AMES TEST-METABOLIC ACTIVATION BY CONJUGATION WITH GLUTATHIONE; J. BIOCHEM. TOXICOL. 4(1):21-27, 1989; SHIMADA,T,  et. al.; ACTIVITIES OF CHLORINATED ETHANE AND ETHYLENE COMPOUNDS IN THE SALMONELLA/RAT MICROSOME MUTAGENESIS AND RAT HEPATOCYTE/DNA REPAIR ASSAYS UNDER VAPOR PHASE EXPOSURE CONDITIONS; CELL BIOL. TOXICOL. 1(3):159-179, 1985
920-37-6	2-Chloroacrylonitrile	C=C(Cl)C#N	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Eder, E., C. Deininger, E. Weinfurtner, Genotoxicity of 2-Halosubstituted Enals and 2-Chloroacrylonitrile in the Ames Test and the SOS Chromotest, Mutat. Res. 322 (1994), 321 – 328
2303-16-4	Diallate; Carbamic acid, diisopropylthio-, S-(2,3-dichloroallyl) ester	CC(C)N(C(C)C)C(=O)SCC(Cl)=CCl	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	SANDHU,SS, WATERS,MD, MORTELMANS,KE, EVANS,EL, JOTZ,MM, MITCHELL,AD AND KASICA, V; EVALUATION OF DIALLATE AND TRIALLATE HERBICIDES FOR GENOTOXIC EFFECTS IN A BATTERY OF IN VITRO AND SHORT-TERM IN VIVO TESTS; MUTAT. RES. 136(6):173-183, 1984
2303-17-5	Tri-allate	CC(C)N(C(C)C)C(=O)SCC(Cl)=C(Cl)Cl	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	De Lorenzo, F., Staiano, N., Silengo, L., Cortese, R., Mutagenicity of Diallate, Sulfallate, and Triallate and Relationship Between Structure and Mutagenic Effects of Carbamates Used Widely in Agriculture. Cancer Res., 1978, 38(1), 13 – 15