CAS Chem.name Chem.SMILES #Observed Mutagenicity without S9 #Observed Mutagenicity with S9 Bioassay - Reference(s) - 55936-76-0 Benzoic_acid,_4-((4-((acetyloxy)methylamino)phenyl)azo)-,_methyl_ester_(9CI) CC(=O)ON(C)c1ccc(N=Nc2ccc(C(=O)OC)cc2)cc1 in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25 55936-77-1 Benzenamine,_N-(acetyloxy)-N-methyl-4-(phenylazo)-_(9CI) CC(=O)ON(C)c1ccc(N=Nc2ccccc2)cc1 in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) U.S.Environmental Protection Agency Gene-Tox Program. Mutation Research, 168, (1996) pp. 69-240 124617-83-0 n-(acetyloxy)-n-ethoxybenzamide CCON(C(=O)c1ccccc1)OC(C)=O in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) GERDES,RG, GLOVER,SA, TEN HAVE,JF AND ROWBOTTOM,CA; TETRAHEDRON LETT. 30(20):26492652, 1989; BONIN,AM BANKS,TM CAMPBELL,JJ GLOVER,SA HAMMOND,GP PRAKASH,AS AND ROWBOTTOM,CA; MUTAT. RES. 494(12):115134, 2001 124617-86-3 n-(acetyloxy)-n-(phenylmethoxy)benzamide CC(=O)ON(C(=O)c1ccccc1)OCc1ccccc1 in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) GERDES,RG, GLOVER,SA, TEN HAVE,JF AND ROWBOTTOM,CA; TETRAHEDRON LETT. 30(20):26492652, 1989; BONIN,AM BANKS,TM CAMPBELL,JJ GLOVER,SA HAMMOND,GP PRAKASH,AS AND ROWBOTTOM,CA; MUTAT. RES. 494(12):115134, 2001 131229-60-2 n-(acetyloxy)-n-butoxy-4-methoxybenzamide CCCCON(C(=O)c1ccc(OC)cc1)OC(C)=O in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Bonin, Am., Banks, Tm., Campbell, Jj., Glover, Sa., Hammond, Gp., Prakash, As. and Rowbottom, Ca.; Mutagenicity Of Electrophilic N-Acyloxy-N-Alkoxyamides; Mutat. Res. 494(1-2):115-134, 2001 131229-61-3 n-(acetyloxy)-n-butoxy-4-methylbenzamide CCCCON(C(=O)c1ccc(C)cc1)OC(C)=O in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Bonin, Am., Banks, Tm., Campbell, Jj., Glover, Sa., Hammond, Gp., Prakash, As. and Rowbottom, Ca.; Mutagenicity Of Electrophilic N-Acyloxy-N-Alkoxyamides; Mutat. Res. 494(1-2):115-134, 2001 131229-62-4 n-(acetyloxy)-n-butoxy-4-chlorobenzamide CCCCON(C(=O)c1ccc(Cl)cc1)OC(C)=O in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Bonin, Am., Banks, Tm., Campbell, Jj., Glover, Sa., Hammond, Gp., Prakash, As. and Rowbottom, Ca.; Mutagenicity Of Electrophilic N-Acyloxy-N-Alkoxyamides; Mutat. Res. 494(1-2):115-134, 2001 131229-63-5 n-(acetyloxy)-n-butoxy-4-bromobenzamide CCCCON(C(=O)c1ccc(Br)cc1)OC(C)=O in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Bonin, Am., Banks, Tm., Campbell, Jj., Glover, Sa., Hammond, Gp., Prakash, As. and Rowbottom, Ca.; Mutagenicity Of Electrophilic N-Acyloxy-N-Alkoxyamides; Mutat. Res. 494(1-2):115-134, 2001 139259-64-6 n-(acetyloxy)-n-(1-methylethoxy)benzamide CC(C)ON(OC(C)=O)C(=O)c1ccccc1 in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Bonin, Am., Banks, Tm., Campbell, Jj., Glover, Sa., Hammond, Gp., Prakash, As. and Rowbottom, Ca.; Mutagenicity Of Electrophilic N-Acyloxy-N-Alkoxyamides; Mutat. Res. 494(1-2):115-134, 2001 139259-91-9 n-(acetyloxy)-n-[(4-methoxyphenyl)methoxy]benzamide CC(=O)ON(C(=O)c1ccccc1)OCc1ccc(OC)cc1 in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Bonin, Am., Banks, Tm., Campbell, Jj., Glover, Sa., Hammond, Gp., Prakash, As. and Rowbottom, Ca.; Mutagenicity Of Electrophilic N-Acyloxy-N-Alkoxyamides; Mutat. Res. 494(1-2):115-134, 2001 139259-92-0 n-(acetyloxy)-n-[(4-phenoxyphenyl)methoxy]benzamide CC(=O)ON(C(=O)c1ccccc1)OCc1ccc(Oc2ccccc2)cc1 in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Bonin, Am., Banks, Tm., Campbell, Jj., Glover, Sa., Hammond, Gp., Prakash, As. and Rowbottom, Ca.; Mutagenicity Of Electrophilic N-Acyloxy-N-Alkoxyamides; Mutat. Res. 494(1-2):115-134, 2001 139259-93-1 n-(acetyloxy)-n-[[4-(1,1-dimethylethyl)phenyl]methoxy]benzamide CC(=O)ON(C(=O)c1ccccc1)OCc1ccc(C(C)(C)C)cc1 in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Bonin, Am., Banks, Tm., Campbell, Jj., Glover, Sa., Hammond, Gp., Prakash, As. and Rowbottom, Ca.; Mutagenicity Of Electrophilic N-Acyloxy-N-Alkoxyamides; Mutat. Res. 494(1-2):115-134, 2001 139259-94-2 n-(acetyloxy)-n-[(4-methylphenyl)methoxy]benzamide Cc1ccc(CON(C(=O)c2ccccc2)OC(C)=O)cc1 in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Bonin, Am., Banks, Tm., Campbell, Jj., Glover, Sa., Hammond, Gp., Prakash, As. and Rowbottom, Ca.; Mutagenicity Of Electrophilic N-Acyloxy-N-Alkoxyamides; Mutat. Res. 494(1-2):115-134, 2001 139259-96-4 n-(acetyloxy)-n-[(4-chlorophenyl)methoxy]benzamide CC(=O)ON(C(=O)c1ccccc1)OCc1ccc(Cl)cc1 in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Bonin, Am., Banks, Tm., Campbell, Jj., Glover, Sa., Hammond, Gp., Prakash, As. and Rowbottom, Ca.; Mutagenicity Of Electrophilic N-Acyloxy-N-Alkoxyamides; Mutat. Res. 494(1-2):115-134, 2001 139259-97-5 n-(acetyloxy)-n-[(4-bromophenyl)methoxy]benzamide CC(=O)ON(C(=O)c1ccccc1)OCc1ccc(Br)cc1 in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Bonin, Am., Banks, Tm., Campbell, Jj., Glover, Sa., Hammond, Gp., Prakash, As. and Rowbottom, Ca.; Mutagenicity Of Electrophilic N-Acyloxy-N-Alkoxyamides; Mutat. Res. 494(1-2):115-134, 2001 139259-98-6 n-(acetyloxy)-n-[(4-nitrophenyl)methoxy]benzamide CC(=O)ON(OCc1ccc(cc1)[N+]([O-])=O)C(=O)c1ccccc1 in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Bonin, Am., Banks, Tm., Campbell, Jj., Glover, Sa., Hammond, Gp., Prakash, As. and Rowbottom, Ca.; Mutagenicity Of Electrophilic N-Acyloxy-N-Alkoxyamides; Mutat. Res. 494(1-2):115-134, 2001 244775-76-6 n-(acetyloxy)-n-propoxybenzamide CCCON(C(=O)c1ccccc1)OC(C)=O in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Bonin, Am., Banks, Tm., Campbell, Jj., Glover, Sa., Hammond, Gp., Prakash, As. and Rowbottom, Ca.; Mutagenicity Of Electrophilic N-Acyloxy-N-Alkoxyamides; Mutat. Res. 494(1-2):115-134, 2001 357204-47-8 n-(acetyloxy)-n-butoxy-3-nitrobenzamide CCCCON(OC(C)=O)C(=O)c1cccc(c1)[N+]([O-])=O in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Bonin, Am., Banks, Tm., Campbell, Jj., Glover, Sa., Hammond, Gp., Prakash, As. and Rowbottom, Ca.; Mutagenicity Of Electrophilic N-Acyloxy-N-Alkoxyamides; Mutat. Res. 494(1-2):115-134, 2001 357204-50-3 n-(acetyloxy)-n-butoxy-2-naphthalenecarboxamide CCCCON(C(=O)c1ccc2ccccc2c1)OC(C)=O in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Bonin, Am., Banks, Tm., Campbell, Jj., Glover, Sa., Hammond, Gp., Prakash, As. and Rowbottom, Ca.; Mutagenicity Of Electrophilic N-Acyloxy-N-Alkoxyamides; Mutat. Res. 494(1-2):115-134, 2001 145142-70-7 n-(acetyloxy)-n-butoxy-[1,1'-biphenyl]-4-carboxamide CCCCON(C(=O)c1ccc(-c2ccccc2)cc1)OC(C)=O in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Bonin, Am., Banks, Tm., Campbell, Jj., Glover, Sa., Hammond, Gp., Prakash, As. and Rowbottom, Ca.; Mutagenicity Of Electrophilic N-Acyloxy-N-Alkoxyamides; Mutat. Res. 494(1-2):115-134, 2001 6098-44-8 n-acetoxy-2-acetylaminofluorene CC(=O)N(c1ccc2c(Cc3ccccc-23)c1)OC(C)=O in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25 26541-56-0 n-acetoxy-4-(acetylamino)biphenyl CC(=O)N(c1ccc(-c2ccccc2)cc1)OC(C)=O in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25 116505-02-3 4-n-acetoxy-n-acetylaminodiphenyl thioether CC(=O)N(c1ccc(Sc2ccccc2)cc1)OC(C)=O in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) JUNEJA,TR, KAUR,B AND GUPTA,RL; MUTAT. RES. 263(1):1319, 1991 172374-60-6 n-[4-[4-(acetylamino)phenoxy]phenyl]-n-(acetyloxy)acetamide CC(=O)Nc1ccc(Oc2ccc(N(C(C)=O)OC(C)=O)cc2)cc1 in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) GUPTA,RL, KAUR,IP AND JUNEJA,TR; MUTAT. RES. 335(3):235243, 1995 31386-38-6 Hydroxylamine, N,O-Diacetyl-N-(P-Ethoxyphenyl)- CCOc1ccc(N(C(C)=O)OC(C)=O)cc1 in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory