CAS	Chem.name	Chem.SMILES	#Observed Mutagenicity without S9	#Observed Mutagenicity with S9	Bioassay - 	Reference(s) -
607-57-8	2-Nitro-9H-fluorene	[O-][N+](=O)c1ccc2c(Cc3ccccc3-2)c1	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	U.S.Environmental Protection Agency Gene-Tox Program. Mutation Research, 168, (1986) pp. 69-240
606-37-1	1,3-Dinitronaphthalene	[O-][N+](=O)c1cc2ccccc2c(c1)[N+]([O-])=O	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
2243-61-0	1,4-Naphthylenediamine	Nc1ccc(N)c2ccccc12	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
2243-62-1	1,5-Naphthalenediamine	Nc1cccc2c(N)cccc12	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
53-95-2	N-Hydroxy-2-acetamidofluorene	CC(=O)N(O)c1ccc2c(Cc3ccccc3-2)c1	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	U.S.Environmental Protection Agency Gene-Tox Program. Mutation Research, 168, (1986) pp. 69-240
6610-08-8	Naphthalene, 2-nitroso-	O=Nc1ccc2ccccc2c1	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
108100-28-3	9H-Fluorene, 2-methyl-7-nitro-	Cc1ccc2c(Cc3cc(ccc3-2)[N+]([O-])=O)c1	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
188107-70-2	9-Methyl-2-nitrocarbazole	[O-][N+](=O)c1ccc2c(c1)[n+](c1ccccc21)C	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
3468-63-1	Pigment orange 5	Oc1ccc2ccccc2c1N=Nc1ccc(cc1[N+]([O-])=O)[N+]([O-])=O	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
613-47-8	Hydroxylamine, N-2-naphthyl-	ONc1ccc2ccccc2c1	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
389104-57-8	1-Isopropyl-9H-fluoren-2-ylamine	CC(C)c1c(N)ccc2-c3ccccc3Cc21	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
31551-45-8	2,7-Dinitro-9H-fluoren-9-one	[O-][N+](=O)c1ccc2c(c1)C(=O)c1cc(ccc1-2)[N+]([O-])=O	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
602-38-0	1,8-Dinitronaphthalene	[O-][N+](=O)c1cccc2cccc(c21)[N+]([O-])=O	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
602-60-8	9-Nitroanthracene	[O-][N+](=O)c1c2ccccc2cc2ccccc21	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
602-87-9	5-Nitroacenaphthene	[O-][N+](=O)c1ccc2CCc3cccc1c32	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
605-71-0	1,5-Dinitronaphthalene	[O-][N+](=O)c1cccc2c(cccc12)[N+]([O-])=O	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
86-57-7	1-Nitronaphthalene	[O-][N+](=O)c1cccc2ccccc21	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
42397-64-8	1,6-Dinitropyrene	[O-][N+](=O)c1ccc2ccc3c(ccc4ccc1c2c43)[N+]([O-])=O	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
42397-65-9	1,8-Dinitropyrene	[O-][N+](=O)c1ccc2ccc3ccc(c4ccc1c2c34)[N+]([O-])=O	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
128714-75-0	1,6-Dinitrobenzo(a)pyrene	[O-][N+](=O)c1ccc2ccc3c(c4ccccc4c4ccc1c2c43)[N+]([O-])=O	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
128714-76-1	3,6-Dinitrobenzo(a)pyrene	[O-][N+](=O)c1ccc2ccc3c4ccccc4c(c4ccc1c2c34)[N+]([O-])=O	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
3025-77-2	1-((4-Nitrophenyl)azo)-2-naphthalenamine	Nc1ccc2ccccc2c1N=Nc1ccc(cc1)[N+]([O-])=O	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
188107-72-4	1,4,6-Trimethyl-3-nitrocarbazole	Cc1ccc2[nH]c3c(C)cc(c(C)c3c2c1)[N+]([O-])=O	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
72917-35-2	1,4-Dimethyl-6-hydroxy-3-nitrocarbazole	Cc1cc(c(C)c2c3cc(O)ccc3[nH]c12)[N+]([O-])=O	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
129117-54-0	1,4-Dimethyl-6-methoxy-3-aminocarbazole	COc1ccc2[nH]c3c(C)cc(N)c(C)c3c2c1	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
6344-66-7	Fluoren-3-amine	Nc1ccc2Cc3ccccc3-c2c1	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
53-94-1	Hydroxylamine, N-fluoren-2-yl-	ONc1ccc2c(Cc3ccccc3-2)c1	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	U.S.Environmental Protection Agency Gene-Tox Program. Mutation Research, 168, (1986) pp. 69-240
607-30-7	1-Naphthylhydroxylamine	ONc1cccc2ccccc12	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
95331-48-9	Acetamide, N-hydroxy-N-1-pyrenyl-	CC(=O)N(O)c1ccc2ccc3cccc4ccc1c2c34	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Ball, LM, Kohan, MJ, Claxton, LD and Lewtas, J;Mutagenicity of Derivatives and Metabolites of 1-Nitropyrene: Activation by Rat Liver S9 and Bacterial Enzymes; Mutat. Res. 138(2-3):113-125, 1984
144425-09-2	9-Methoxytariacuripyrone	COc1ccc2cc(c3C=CC(=O)Oc3c2c1)[N+]([O-])=O	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Schimmer, O. and Drewello,U; 9-Methoxytariacuripyrone, a Naturally Occurring Nitro-Aromatic Compound with Strong Mutagenicity in Salmonella Typhimurium; Mutagenesis 9(6):547-551, 1994
*6-01-8	ICR 415	CCN(CCCl)CCOCCNc1c2ccc(Cl)cc2nc2ccc(OC)nc12	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	DeMarini D.M.,et.al, Relationships between structures and mutagenic potencies of 16 heterocyclic nitrogen mustards (ICR compounds) in Salmonella typhimurium Mut.Research, 136 (1984) 185-199
62450-06-0	Trp-P-1	Cc1nc(N)c(C)c2[nH]c3ccccc3c12	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
90-45-9	9-Aminoacridine	Nc1c2ccccc2nc2ccccc12	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
153-78-6	2-Aminofluorene	Nc1ccc2c(Cc3ccccc3-2)c1	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	O'DONOVAN,MR; THE COMPARATIVE RESPONSES OF SALMONELLA TYPHIMURIUM TA1537 AND TA97A TO A RANGE OF REFERENCE MUTAGENS AND NOVEL COMPOUNDS; MUTAGENESIS 5(3):267-274, 1990
613-13-8	2-Anthracenamine	Nc1ccc2cc3ccccc3cc2c1	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Diehl, M. And Fort, F.; Spiral Salmonella Assay: Validation Against The Standard Pour-Plate Assay; Environ. Mol. Mutagen. 27(3):227-236, 1996
1606-67-3	1-Aminopyrene	Nc1ccc2ccc3cccc4ccc1c2c34	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Ball, LM, Kohan, MJ, Claxton, LD and Lewtas, J;Mutagenicity of Derivatives and Metabolites of 1-Nitropyrene: Activation by Rat Liver S9 and Bacterial Enzymes; Mutat. Res. 138(2-3):113-125, 1984
389104-56-7	Fluorene, 1-ethyl-2-amino-	CCc1c(N)ccc2c1Cc1ccccc1-2	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	GLENDE,C. et al; TRANSFORMATION OF MUTAGENIC AROMATIC AMINES INTO NON-MUTAGENIC SPECIES BY ALKYL SUBSTITUENTS. PART I. ALKYLATION ORTHO TO THE AMINO FUNCTION. MUTAT. RES. 498(1-2):19-37, 2001
89459-43-8	N-((2-Dimethylamino)ethyl)-9-aminoacridine-4-carboxamide	CN(C)CCNC(=O)c1cccc2c(N)c3ccccc3nc12	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
4637-56-3	4-Hydroxyaminoquinoline-1-oxide	ONc1cc[n+]([O-])c2ccccc12	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
2508-20-5	2-Nitrosofluorene	O=Nc1ccc2c(Cc3ccccc3-2)c1	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
389104-58-9	Fluorene, 1-butyl-2-amino-	CCCCc1c(N)ccc2c1Cc1ccccc1-2	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
126485-28-7	6-amino-3-[[4-[[4-(diethylamino)phenyl]diazenyl]-2-methoxyphenyl]diazenyl]-4-hydroxynaphthalene-2-sulfonic acid	CCN(CC)c1ccc(cc1)N=NC1=CCC(N=Nc2c(O)c3cc(N)ccc3cc2S(O)(=O)=O)C(OC)=C1	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
82-75-7	Peri Acid	Nc1cccc2cccc(c12)S(O)(=O)=O	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
134-32-7	1-Naphthylamine	Nc1cccc2ccccc12	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
610-49-1	1-Anthracenamine	Nc1cccc2cc3ccccc3cc12	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
881-03-8	1-Nitro-2-Methylnaphthalene	Cc1ccc2ccccc2c1[N+]([O-])=O	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
2425-85-6	C. I. Pigment Red 3	Cc1ccc(N=Nc2c(O)ccc3ccccc32)c(c1)[N+]([O-])=O	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
3761-53-3	C.I. Acid Red 26	Cc1ccc(N=Nc2c(O)c(cc3cc(ccc32)S(O)(=O)=O)S(O)(=O)=O)c(C)c1	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
28322-02-3	4-Acetylaminofluorene	CC(=O)Nc1cccc2Cc3ccccc3-c21	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
67219-70-9	1-Butyl-2-Aminonaphthalene; 1-Butyl-naphthalen-2-ylamine	CCCCc1c(N)ccc2ccccc12	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
2508-23-8	N-Hydroxy-N-2-naphthalenylacetamide	CC(=O)N(O)c1ccc2ccccc2c1	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	WANG,CY, LINSMAIER-BEDNAR,EM, LEE,MS AND KING,CM; MUTAGENICITIES OF N-ACYL-N-ARYLHYDROXYLAMINES FOR SALMONELLA; CHEM-BIOL. INTERACT. 67(3-4):215-223, 1988
87-02-5	7-Amino-4-hydroxy-2-naphthalenesulfonic acid	Nc1ccc2c(O)cc(cc2c1)S(O)(=O)=O	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	NIHS Japan
81-16-3	2-Amino-1-naphthalenesulfonic acid	Nc1ccc2ccccc2c1S(O)(=O)=O	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	NIHS Japan
314-13-6	Evans blue	Cc1cc(ccc1N=Nc1ccc2c(cc(c(N)c2c1O)S(O)(=O)=O)S(O)(=O)=O)-c1ccc(N=Nc2ccc3c(cc(c(N)c3c2O)S(O)(=O)=O)S(O)(=O)=O)c(C)c1	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Robertson J., et al., Carcinogenesis, 3(1), 21-25, 1982
553-30-0	Proflavine sulfate	OS(O)(=O)=O.Nc1ccc2cc3ccc(N)cc3nc2c1	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
6109-97-3	Carbazole, 3-amino-9-ethyl-, hydrochloride	[Cl-].CCn1c2ccccc2c2cc([N+H3])ccc21	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
551-06-4	1-Naphthylisothiocyanate	S=C=Nc1cccc2ccccc21	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	ZEIGER,E, ANDERSON,B, HAWORTH,S, LAWLOR,T AND MORTELMANS,K; ENVIRON. MOL. MUTAGEN. 11(SUPPL.12):1-158, 1988
528-74-5	Dichloromethotrexate	CN(Cc1cnc2nc(N)nc(N)c2n1)c1c(Cl)cc(cc1Cl)C(=O)NC(CCC(O)=O)C(O)=O	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	ZEIGER,E,  et. al.; SALMONELLA MUTAGENICITY TESTS: IV. RESULTS FROM THE TESTING OF 300 CHEMICALS; ENVIRON. MOL. MUTAGEN. 11(SUPPL.12):1-158, 1988
3626-28-6	C.I. Direct green 1	[Na+].[Na+].Nc1c(\N=N/c2ccc(cc2)-c2ccc(cc2)\N=N/c2ccc(O)cc2)c(cc2cc(c(\N=N/c3ccccc3)c(O)c12)S([O-])(=O)=O)S([O-])(=O)=O	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
127750-13-4	2-Naphthalenesulfonic acid, 6-amino-4-hydroxy-3-((2-methoxy-4-(phenylazo)phenyl)azo)-, monosodium salt	[Na+].COc1cc(ccc1\N=N/c1c(O)c2cc(N)ccc2cc1S([O-])(=O)=O)\N=N/c1ccccc1	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
313-67-7	Aristolochic acid	COc1cccc2c1cc(c1c(cc3OCOc3c21)C(O)=O)[N+]([O-])=O	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Chakrabarty, Sn., Pakrashi, A. and Siddiqui, Kai.; Aristolic Acid An Antifertility Agent Is Non-Mutagenic To Bacterial System; Indian J. Pharmacol. 19(1):26-31, 1987
573-58-0	c.i. direct red 28;congo red;	[Na+].[Na+].Nc1c(cc(c2ccccc12)S([O-])(=O)=O)N=Nc1ccc(cc1)-c1ccc(cc1)N=Nc1cc(c2ccccc2c1N)S([O-])(=O)=O	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Zhou,Y, You,X and Ye,X; MUTAGENICITY OF BENZIDINES AND THEIR CONGENER DERIVATIVE DYES; HUANJING KEXUE 8(2):31-34, 1987
525-64-4	2,7-diamino-fluoren	Nc1ccc2c(Cc3cc(N)ccc3-2)c1	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	MCCANN,J, CHOI,E, YAMASAKI,E AND AMES,BN; DETECTION OF CARCINOGENS AS MUTAGENS IN THE SALMONELLA/MICROSOME TEST: ASSAY OF 300 CHEMICALS; PROC. NATL. ACAD. SCI. USA 72(12):5135-5139, 1975
607-59-0	Aniline, N,N-dimethyl-p-(1-naphthylazo)-	CN(C)c1ccc(cc1)N=Nc1cccc2ccccc21	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	SHORT-TERM TEST PROGRAM SPONSORED BY THE DIVISION OF CANCER BIOLOGY, NATIONAL CANCER INSTITUTE, MS. ELLEN ZAIKA, ASSISTANT PROJECT OFFICER , p. Y82
33389-36-5	Quinazoline, 4-(2-hydroxyethylamino)-2-(5-nitro-2-thienyl)-	OCCNc1nc(nc2ccccc12)-c1ccc(s1)[N+]([O-])=O	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	MCCANN,J, CHOI,E, YAMASAKI,E AND AMES,BN; DETECTION OF CARCINOGENS AS MUTAGENS IN THE SALMONELLA/MICROSOME TEST: ASSAY OF 300 CHEMICALS; PROC. NATL. ACAD. SCI. USA 72(12):5135-5139, 1975
91-59-8	2-naphthylamine	Nc1ccc2ccccc2c1	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	JORDAN,VC, LABABIDI,MK AND LANGAN-FAHEY,S; SUPPRESSION OF MOUSE MAMMARY TUMORIGENESIS BY LONG-TERM TAMOXIFEN THERAPY; J. NATL. CANCER INST. 83:492-496, 1991
7496-02-8	6-nitrochrysene	[O-][N+](=O)c1cc2c3ccccc3ccc2c2ccccc12	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	EL-BAYOUMY,K, DELCLOS,KB, HEFLICH,RH, WALKER,R, SHIUE,GH AND HECHT,SS; MUTAGENICITY, METABOLISM AND DNA ADDUCT FORMATION OF 6-NITROCHRYSENE IN SALMONELLA TYPHIMURIUM; MUTAGENESIS 4(3):235-240, 1989
581-89-5	2-nitronaphthalene;2nitronaphthalene	[O-][N+](=O)c1ccc2ccccc2c1	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	MCCANN,J, CHOI,E, YAMASAKI,E AND AMES,BN; DETECTION OF CARCINOGENS AS MUTAGENS IN THE SALMONELLA/MICROSOME TEST: ASSAY OF 300 CHEMICALS; PROC. NATL. ACAD. SCI. USA 72(12):5135-5139, 1975
5522-43-0	1-nitropyrene;pyrene, 1-nitro-	[O-][N+](=O)c1ccc2ccc3cccc4ccc1c2c34	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	EL-BAYOUMY,K AND HECHT,SS; MUTAGENICITY OF K-REGION DERIVATIVES OF 1-NITROPYRENE; REMARKABLE ACTIVITY OF 1- AND 3-NITRO-5H-PHENANTHRO[4,5-BCD]PYRAN-5-ONE; MUTAT. RES. 170(1-2):31-40, 1986
607-35-2	8-nitroquinoline;quinoline, 8-nitro-	[O-][N+](=O)c1cccc2cccnc21	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240
8048-52-0	Acriflavine	[Cl-].Nc1ccc2cc3ccc(N)cc3nc2c1.C[n+]1c2cc(N)ccc2cc2ccc(N)cc21	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Brown, Jp. and Brown, Rj.; Mutagenesis by 9,10-Anthraquinone Derivatives and Related Compounds in Salmonella Typhimurium; Mutat. Res. 40:203-224, 1976
72-57-1	c.i. direct blue 14	[Na+].[Na+].[Na+].[Na+].Cc1cc(ccc1/N=N/c1c(O)c2c(N)cc(cc2cc1S([O-])(=O)=O)S([O-])(=O)=O)-c1ccc(/N=N/c2c(O)c3c(N)cc(cc3cc2S([O-])(=O)=O)S([O-])(=O)=O)c(C)c1	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Cancer Institute
3734-67-6	C.I. Acid Red 1	[Na+].[Na+].CC(=O)Nc1cc(cc2cc(c(N=Nc3ccccc3)c(O)c12)S([O-])(=O)=O)S([O-])(=O)=O	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Haveland-Smith, R.B., Combes, R.D., Screening of food dyes for genotoxic activity. Food Cosmet. Toxicol., 1980, 18(3), 215-221.
6428-31-5	2,7-naphthalenedisulfonic acid, 4-amino-3,6-bis[[4-[(2,4-diaminophenyl)azo]phenyl]azo]-5-hydroxy-, disodium salt	[Na+].[Na+].Nc1ccc(N=Nc2ccc(cc2)N=Nc2c(N)c3c(O)c(N=Nc4ccc(cc4)N=Nc4ccc(N)cc4N)c(cc3cc2S([O-])(=O)=O)S([O-])(=O)=O)c(N)c1	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Disodium 4-amino-3,6-bis[[4-[(2,4-diaminophenyl)azo]phenyl]azo]-5-hydroxynaphthalene-2,7-disulphonate, CAS No 6428-31-5. ECHA Legal notice, Registration dossier. http://echa.europa.eu/registration-dossier/-/registered-dossier/11334
3118-97-6	2-naphthalenol, 1- (2,4-dimethylphenyl)azo -; c.i. solvent orange 7	Cc1ccc(N=Nc2c(O)ccc3ccccc32)c(C)c1	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food on a request from the Commission to Review the toxicology of a number of dyes illegally present in food in the EU Question number EFSA-2005-082. EFSA J., 2005, 263, 1-71.
3441-14-3	2-naphthalenesulfonic acid, 3-[[4-(acetylamino)phenyl]azo]-4-hydroxy-7-[[[[5-hydroxy-6-(phenylazo)-7-sulfo-2-naphthalenyl]amino]carbonyl]amino]-, disodium salt	[Na+].[Na+].CC(=O)Nc1ccc(cc1)N=Nc1c(O)c2ccc(NC(=O)Nc3ccc4c(O)c(N=Nc5ccccc5)c(cc4c3)S([O-])(=O)=O)cc2cc1S([O-])(=O)=O	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	C.I. Direct Red 23, CAS No 3441-14-3. TOXNET, CCRIS, 2011.
126513-99-3	2-Naphthalenesulfonic acid, 6-amino-3-((4-((4-(bis(2-hydroxyethyl)amino)phenyl)azo)-2-methoxyphenyl)azo)-4-hydroxy-	COc1cc(ccc1/N=N/c1c(O)c2cc(N)ccc2cc1S(O)(=O)=O)/N=N/c1ccc(cc1)N(CCO)CCO	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
6459-94-5	C.I. Acid Red 114	[Na+].[Na+].Cc1ccc(cc1)S(=O)(=O)Oc1ccc(cc1)/N=N/c1ccc(cc1C)-c1ccc(/N=N/c2c(O)ccc3cc(cc(c32)S([O-])(=O)=O)S([O-])(=O)=O)c(C)c1	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
1937-37-7	C.I. Direct Black 38	[Na+].[Na+].Nc1ccc(N=Nc2ccc(cc2)-c2ccc(cc2)N=Nc2c(N)c3c(O)c(N=Nc4ccccc4)c(cc3cc2S([O-])(=O)=O)S([O-])(=O)=O)c(N)c1	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
5460-09-3	Monosodium 8-amino-1-naphthol-3,6-disulfonate	[Na+].Nc1cc(cc2cc(cc(O)c12)S(O)(=O)=O)S([O-])(=O)=O	in vitro Ames negative	in vitro Ames negative	Bacterial Reverse Mutation Assay (e.g. Ames Test)	NIHS Japan
5281-04-9	D & C Red No. 7	[Ca+2].Cc1ccc(N=Nc2c(O)c(cc3ccccc32)C([O-])=O)c(c1)S([O-])(=O)=O	in vitro Ames negative	in vitro Ames negative	Bacterial Reverse Mutation Assay (e.g. Ames Test)	NIHS Japan
130-13-2	1-Naphthalenesulfonic acid, 4-amino-, sodium salt (1:1)	[Na+].Nc1ccc(c2ccccc12)S([O-])(=O)=O	in vitro Ames negative	in vitro Ames negative	Bacterial Reverse Mutation Assay (e.g. Ames Test)	NIHS Japan
2783-94-0	FD & C Yellow No. 6	[Na+].[Na+].Oc1ccc2cc(ccc2c1/N=N/c1ccc(cc1)S([O-])(=O)=O)S([O-])(=O)=O	in vitro Ames negative	in vitro Ames negative	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Invenrory
17095-24-8	reactive black 5	[Na+].[Na+].[Na+].[Na+].Nc1c(N=Nc2ccc(cc2)S(=O)(=O)CCOS([O-])(=O)=O)c(cc2cc(c(N=Nc3ccc(cc3)S(=O)(=O)CCOS([O-])(=O)=O)c(O)c12)S([O-])(=O)=O)S([O-])(=O)=O	in vitro Ames negative	in vitro Ames negative	Bacterial Reverse Mutation Assay (e.g. Ames Test)	CI Reactive Black 5, CAS No 17095-24-8. TOXNET, CCRIS, 2011.
633-96-5	c.i. acid orange 7, monosodium salt	[Na+].Oc1ccc2ccccc2c1N=Nc1ccc(cc1)S([O-])(=O)=O	in vitro Ames negative	in vitro Ames negative	Bacterial Reverse Mutation Assay (e.g. Ames Test)	SCCS (Scientific Committee on Consumer Safety), Opinion on Acid Orange 7, 18 June 2014, SCCS/1536/14, revision of 23 September 2014.
5858-81-1	c.i. pigment red 57, disodium salt	[Na+].[Na+].Cc1ccc(N=Nc2c(O)c(cc3ccccc32)C([O-])=O)c(c1)S([O-])(=O)=O	in vitro Ames negative	in vitro Ames negative	Bacterial Reverse Mutation Assay (e.g. Ames Test)	SCCNFP (Scientific Committee on Cosmetic Products and Non-Food Products Intended for Consumers), Evaluation and opinion on Pigment Red 57, 25 May 2004.
7023-61-2	2-naphthalenecarboxylic acid, 4-[(5-chloro-4-methyl-2-sulfophenyl)azo]-3-hydroxy-, calcium salt (1:1)	[Ca+2].Cc1cc(c(cc1Cl)N=Nc1c(O)c(cc2ccccc21)C([O-])=O)S([O-])(=O)=O	in vitro Ames negative	in vitro Ames negative	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Calcium 4-[(5-chloro-4-methyl-2-sulphonatophenyl)azo]-3-hydroxy-2-naphthoate, CAS No 7023-61-2. ECHA Legal notice, Registration dossier. http://echa.europa.eu/registration-dossier/-/registered-dossier/15275
7585-41-3	2-naphthalenecarboxylic acid, 4-[(5-chloro-4-methyl-2-sulfophenyl)azo]-3-hydroxy-, barium salt (1:1)	[Ba+2].Cc1cc(c(cc1Cl)N=Nc1c(O)c(cc2ccccc21)C([O-])=O)S([O-])(=O)=O	in vitro Ames negative	in vitro Ames negative	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Barium 4-[(5-chloro-4-methyl-2-sulphonatophenyl)azo]-3-hydroxy-2-naphthoate, CAS No 7585-41-3. ECHA Legal notice, Registration dossier. http://echa.europa.eu/registration-dossier/-/registered-dossier/14735
187674-70-0	1,5-naphthalenedisulfonic acid, 3-[2-[4-[[4,6-bis[(3-sulfopropyl)thio]-1,3,5-triazin-2-yl]amino]-5-methoxy-2-methylphenyl]diazenyl]-	[Na+].COc1cc(N=Nc2cc(c3cccc(c3c2)S(O)(=O)=O)S([O-])(=O)=O)c(C)cc1Nc1nc(SCCCS(O)(=O)=O)nc(SCCCS(O)(=O)=O)n1	in vitro Ames negative	in vitro Ames negative	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Tetrasodium 3-[[4-[[4,6-bis-[(3-sulfonatoprop-1-yl)thio]-1,3,5-triazin-2-yl]amino]-2-methyl-5-methoxy-phenyl]azonaphthalene-1,5-disulfonate, EC number 421-950-6. ECHA Legal notice, Registration dossier. http://echa.europa.eu/registration-dossier/-/registered-dossier/8050
3567-66-6	c.i. acid red 33, disodium salt	[Na+].[Na+].Nc1cc(cc2cc(c(N=Nc3ccccc3)c(O)c12)S([O-])(=O)=O)S([O-])(=O)=O	in vitro Ames negative	in vitro Ames negative	Bacterial Reverse Mutation Assay (e.g. Ames Test)	SCCP (Scientific Committee on Consumer Products), Opinion on Acid Red 33, 18 December 2007.