CAS Chem.name Chem.SMILES #Observed Mutagenicity without S9 #Observed Mutagenicity with S9 Bioassay - Reference(s) - 78-87-5 1,2-Dichloro-Propane CC(Cl)CCl in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) U.S.Environmental Protection Agency Gene-Tox Program. Mutation Research, 168, (1986) pp. 69-240 100-14-1 P-Nitrobenzyl Chloride [O-][N+](=O)c1ccc(CCl)cc1 in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25 100-39-0 Alpha-Bromotoluene BrCc1ccccc1 in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25 106-93-4 1,2-Dibromoethane BrCCBr in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25 540-51-2 2-Bromo-1-Ethanol OCCBr in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25 542-75-6 1,3-Dichloropropene; 1-Propene, 1,3-Dichloro ClCC=CCl in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25 79-08-3 Bromoacetic Acid OC(=O)CBr in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 6959-47-3 2-(Chloromethyl)Pyridine_Hydrohloride ClCc1ccccn1 in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25 6959-48-4 3-(Chloromethyl)Pyridine.HCl ClCc1cccnc1 in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25 554-10-9 3-Iodo-1,2-Propanediol OCC(O)CI in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25 612-23-7 O-Nitrobenzyl Chloride [O-][N+](=O)c1ccccc1CCl in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25 616-23-9 2,3-Dichloro-1-Propanol OCC(Cl)CCl in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25 619-23-8 M-Nitrobenzyl Chloride [O-][N+](=O)c1cccc(CCl)c1 in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25 627-18-9 3-Bromo-1-Propanol OCCCBr in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25 66-75-1 Uracil Mustard Oc1c(N(CCCl)CCCl)cnc(O)n1 in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 74-96-4 Ethyl Bromide CCBr in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 78-88-6 2,3-Dichloro-1-Propene C=C(Cl)CCl in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) U.S.Environmental Protection Agency Gene-Tox Program. Mutation Research, 168, (1986) pp. 69-240 96-13-9 2,3-Dibromo-1-Propanol OCC(Br)CBr in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25 98-87-3 Alpha,Alpha-Dichlorotoluene ClC(Cl)c1ccccc1 in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25 75-00-3 Ethy Chloride CCCl in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 7166-19-0 Beta-Bromo-Beta-Nitrostyrene [O-][N+](=O)C(Br)=Cc1ccccc1 in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25 154-93-8 Carmustine O=C(NCCCl)N(CCCl)N=O in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25 494-03-1 Chlornaphazine ClCCN(CCCl)c1ccc2ccccc2c1 in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25 *6-00-3 ICR 174 (13441-95-7); CCN(CCCNc1ccnc2ccc(OC)cc12)CCCl in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) DeMarini D.M.,et.al, Relationships between structures and mutagenic potencies of 16 heterocyclic nitrogen mustards (ICR compounds) in Salmonella typhimurium Mut.Research, 136 (1984) 185-199 *6-00-5 ICR 360 CCN(CCCNc1c2ccccc2nc2c1C(C)(C)C(C)(C)C(C)(C)C2(C)C)CCCl in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) DeMarini D.M.,et.al, Relationships between structures and mutagenic potencies of 16 heterocyclic nitrogen mustards (ICR compounds) in Salmonella typhimurium Mut.Research, 136 (1984) 185-199 *6-00-8 ICR 224 CCN(CCCNc1c2ccccc2nc2ccc(OC)cc12)CCCl in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) DeMarini D.M.,et.al, Relationships between structures and mutagenic potencies of 16 heterocyclic nitrogen mustards (ICR compounds) in Salmonella typhimurium Mut.Research, 136 (1984) 185-199 *6-01-1 ICR 377 CCN(CCCNc1c2ccccc2nc2c1cccc2OC)CCCl in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) DeMarini D.M.,et.al, Relationships between structures and mutagenic potencies of 16 heterocyclic nitrogen mustards (ICR compounds) in Salmonella typhimurium Mut.Research, 136 (1984) 185-199 *6-01-4 ICR 397 CCN(CCOCCNc1c2ccc(Cl)cc2nc2ccc(OC)cc12)CCCl in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) DeMarini D.M.,et.al, Relationships between structures and mutagenic potencies of 16 heterocyclic nitrogen mustards (ICR compounds) in Salmonella typhimurium Mut.Research, 136 (1984) 185-199 *6-01-7 ICR 340 CCN(CCCNc1c2ccc(Cl)cc2nc2ccc(OC)nc12)CCCl in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) DeMarini D.M.,et.al, Relationships between structures and mutagenic potencies of 16 heterocyclic nitrogen mustards (ICR compounds) in Salmonella typhimurium Mut.Research, 136 (1984) 185-199 *6-01-8 ICR 415 CCN(CCOCCNc1c2ccc(Cl)cc2nc2ccc(OC)nc12)CCCl in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) DeMarini D.M.,et.al, Relationships between structures and mutagenic potencies of 16 heterocyclic nitrogen mustards (ICR compounds) in Salmonella typhimurium Mut.Research, 136 (1984) 185-199 *6-02-0 ICR 355 CCCCOc1ccc2c(c(NCCCN(CC)CCCl)c3ccc(Cl)cc3n2)n1 in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) DeMarini D.M.,et.al, Relationships between structures and mutagenic potencies of 16 heterocyclic nitrogen mustards (ICR compounds) in Salmonella typhimurium Mut.Research, 136 (1984) 185-199 *6-02-2 ICR 292 CCN(CCCNc1c2ccccc2nc2c1ccc1ccccc21)CCCl in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) DeMarini D.M.,et.al, Relationships between structures and mutagenic potencies of 16 heterocyclic nitrogen mustards (ICR compounds) in Salmonella typhimurium Mut.Research, 136 (1984) 185-199 *6-02-4 ICR 368 CCN(CCCNc1c2ccccc2nc2c1ccc1cccnc21)CCCl in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) DeMarini D.M.,et.al, Relationships between structures and mutagenic potencies of 16 heterocyclic nitrogen mustards (ICR compounds) in Salmonella typhimurium Mut.Research, 136 (1984) 185-199 4213-45-0 Quinacrine mustard dihydrochloride; Acridine,_9-__4-_bis(2-chloroethyl)amino_-1-methylbutyl_amino_-6-chloro-2-metho CC(CCCN(CCCl)CCCl)Nc1c2ccc(Cl)cc2nc2ccc(OC)cc12_Cl_Cl in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25 146-59-8 Acridine mustard (ICR 170) CCN(CCCNc1c2ccc(Cl)cc2nc2ccc(OC)cc12)CCCl_Cl_Cl in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) DeMarini D.M.,et.al, Relationships between structures and mutagenic potencies of 16 heterocyclic nitrogen mustards (ICR compounds) in Salmonella typhimurium Mut.Research, 136 (1984) 185-199 611-19-8 Benzene,1-chloro-2-(chloromethyl)- ClCc1ccccc1Cl in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) NIHS Japan 112-26-5 1,2-Bis(2-chloroethoxy)ethane ClCCOCCOCCCl in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) NIHS Japan 109-70-6 1-bromo-3-chloropropane;_Propane,_1-bromo-3-chloro- ClCCCBr in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) NIHS Japan 79-11-8 Chloroacetic acid OC(=O)CCl in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) KARGALIOGLU,Y MCMILLAN,BJ MINEAR,RA AND PLEWA,MJ; ANALYSIS OF THE CYTOTOXICITY AND MUTAGENICITY OF DRINKING WATER DISINFECTION BY-PRODUCTS IN SALMONELLA TYPHIMURIUM; TERATOG. CARCINOG. MUTAGEN. 22(2):113-128, 2002 100-44-7 Benzyl chloride ClCc1ccccc1 in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25 563-47-3 3-Chloro-2-methylprop-1-ene CC(=C)CCl in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25 77439-76-0 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5h)-furanone;mx;3-chloro-4-dichloromethyl-5-hydroxy-2-furanone OC1C(C(Cl)Cl)=C(Cl)C(=O)O1 in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25 97055-38-4 3-chloro-4-(dichloromethyl)-5-methoxy-2(5h)-furanone COC1C(C(Cl)Cl)=C(Cl)C(=O)O1 in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25 122551-89-7 3-chloro-4-(dichloromethyl)-2(5h)-furanone;3-chloro-4-(dichloromethyl)-2-(5h)-furanone O=C1C(Cl)=C(C(Cl)Cl)CO1 in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) LALONDE,RT, COOK,GP, PERAKYLA,H, DENCE,CW AND BABISH,JG; ENVIRON. MOL. MUTAGEN. 17(1):4048, 1991; KRONBERG,L, CHRISTMAN,RF, SINGH,R, AND BALL,LM; ENVIRON. SCI. TECHNOL. 25(1):99104, 1991 125974-01-8 3-chloro-4-(chloromethyl)-2(5h)-furanone O=C1C(Cl)=C(CCl)CO1 in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) LALONDE,RT, COOK,GP, PERAKYLA,H AND BU,L, CHEM. RES. TOXICOL. 4(5):540545, 1991; LALONDE,RT, BU,L, HENWOOD,A, FIUMANO,J AND ZHANG,L; CHEM. RES. TOXICOL. 10(12):14271436, 1997 125974-08-5 3-chloro-4-(chloromethyl)-5-hydroxy-2(5h)-furanone OC1C(CCl)=C(Cl)C(=O)O1 in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) LALONDE,RT, COOK,GP, PERAKYLA,H AND BU,L, CHEM. RES. TOXICOL. 4(5):540545, 1991; LALONDE,RT, BU,L, HENWOOD,A, FIUMANO,J AND ZHANG,L; CHEM. RES. TOXICOL. 10(12):14271436, 1997; NIITTYKOSKI,M, HYTTINEN,JMT AND JANSSON,K; MUTAT. RES. 348(1):5155, 1995 132059-52-0 3-chloro-4-(dibromomethyl)-5-hydroxy-2(5h)-furanone OC1C(C(Br)Br)=C(Cl)C(=O)O1 in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) SUZUKI,N AND MATSUO,T; J. FAC. ENG. UNIV. TOKYO, SER.B 42(4):307315, 1994; LALONDE,RT, BU,L, HENWOOD,A, FIUMANO,J AND ZHANG,L;CHEM. RES. TOXICOL. 10(12):14271436, 1997; RAMOS,I LLOVERAS,M SOLANS,X HUICI,A AND MESSEGUER,A; ENVIRON. TOXICOL. CHEM. 19(11):26312636, 2000 132059-53-1 3-bromo-4-(dibromomethyl)-5-hydroxy-2(5h)-furanone OC1C(C(Br)Br)=C(Br)C(=O)O1 in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) SUZUKI,N AND MATSUO,T; J. FAC. ENG. UNIV. TOKYO, SER.B 42(4):307315, 1994; LALONDE,RT, BU,L, HENWOOD,A, FIUMANO,J AND ZHANG,L;CHEM. RES. TOXICOL. 10(12):14271436, 1997; RAMOS,I LLOVERAS,M SOLANS,X HUICI,A AND MESSEGUER,A; ENVIRON. TOXICOL. CHEM. 19(11):26312636, 2000 199536-62-4 3-bromo-4-(bromomethyl)-2(5h)-furanone O=C1C(Br)=C(CBr)CO1 in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) LALONDE,RT, BU,L, HENWOOD,A, FIUMANO,J AND ZHANG,L;CHEM. RES. TOXICOL. 10(12):14271436, 1997 199536-64-6 3-bromo-4-(bromomethyl)-5-hydroxy-2(5h)-furanone OC1C(CBr)=C(Br)C(=O)O1 in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) LALONDE,RT, BU,L, HENWOOD,A, FIUMANO,J AND ZHANG,L;CHEM. RES. TOXICOL. 10(12):14271436, 1997 199536-65-7 3-chloro-4-(bromomethyl)-2(5h)-furanone O=C1C(Cl)=C(CBr)CO1 in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) LALONDE,RT, BU,L, HENWOOD,A, FIUMANO,J AND ZHANG,L; CHEM. RES. TOXICOL. 10(12):14271436, 1997 199536-79-3 3-bromo-4-(dibromomethyl)-2(5h)-furanone O=C1C(Br)=C(C(Br)Br)CO1 in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) LALONDE,RT, BU,L, HENWOOD,A, FIUMANO,J AND ZHANG,L; CHEM. RES. TOXICOL. 10(12):14271436, 1997 199536-82-8 3-chloro-4-(dibromomethyl)-2(5h)-furanone O=C1C(Cl)=C(C(Br)Br)CO1 in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) LALONDE,RT, BU,L, HENWOOD,A, FIUMANO,J AND ZHANG,L; CHEM. RES. TOXICOL. 10(12):14271436, 1997 199536-84-0 3-bromo-4-(chloromethyl)-2(5h)-furanone O=C1C(Br)=C(CCl)CO1 in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) LALONDE,RT, BU,L, HENWOOD,A, FIUMANO,J AND ZHANG,L; CHEM. RES. TOXICOL. 10(12):14271436, 1997 79-00-5 1,1,2-Trichloroethane ClCC(Cl)Cl in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) STROBEL,K AND GRUMMT,T; ALIPHATIC AND AROMATIC HALOCARBONS AS POTENTIAL MUTAGENS IN DRINKING WATER. III. HALOGENATED ETHANES AND ETHENES; TOXICOL. ENVIRON. CHEM. 15(1-2):101-128, 1987; 107-07-3 2-Chloroethanol OCCCl in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Toxicology and Carcinogenesis Studies of 2-Chloroethanol (Ethylene Chlorohydrin) (CAS No. 107-07-3) in F344/N Rats and Swiss CD-1 Mice (Dermal Studies), US Dept. of Health and Human Services, Public health Service, NIH, November 1985 107-06-2 1,2-Dichloro-ethane ClCCCl in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 4823-47-6 Acrylic acid, 2-bromoethyl ester C=CC(=O)OCCBr in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 38914-97-5 ICR 217 CCN(CCCNc1c2ccccc2nc2ccccc12)CCCl_Cl_Cl in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) DeMarini D.M.,et.al, Relationships between structures and mutagenic potencies of 16 heterocyclic nitrogen mustards (ICR compounds) in Salmonella typhimurium Mut.Research, 136 (1984) 185-199 96-18-4 1,2,3-Trichloropropane ClCC(Cl)CCl in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 108-60-1 Bis(2-Chloro-1-Methylethyl)Ether CC(CCl)OC(C)CCl in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 109-64-8 1,3-Dibromopropane BrCCCBr in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 111-44-4 1-Chloro-2-(2-chloro-ethoxy)-ethane; Bis(2-Chloroethyl)Ether ClCCOCCCl in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 126-72-7 Tris(2,3-Dibromopropyl)Phosphate O=P(OCC(Br)CBr)(OCC(Br)CBr)OCC(Br)CBr in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 627-30-5 3-Chloro-1-Propanol OCCCCl in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 2206-89-5 2-Chloroethyl Acrylate C=CC(=O)OCCCl in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 3066-70-4 2-Propenoic_acid,_2-methyl-,_2,3-dibromopropyl_ester CC(=C)C(=O)OCC(Br)CBr in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 19660-16-3 2,3-Dibromopropyl crylate C=CC(=O)OCC(Br)CBr in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 75-35-4 1,1-Dichloroethylene C=C(Cl)Cl in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) STROBEL,K AND GRUMMT,T; ALIPHATIC AND AROMATIC HALOCARBONS AS POTENTIAL MUTAGENS IN DRINKING WATER. III. HALOGENATED ETHANES AND ETHENES; TOXICOL. ENVIRON. CHEM. 15(1-2):101-128, 1987; GOTO,S, SHIRAISHI,F, TANABE,K, ENDO,O, MACHII,K, TEZUKA,Y, ISHII,T AND MATSUSHITA,H; MUTAGENICITY DETECTION METHOD FOR VINYL CHLORIDE AND VINYLIDENE CHLORIDE GASES; KANKYO KAGAKU 5(2):235-240, 1995 34256-82-1 Acetochlor CCc1cccc(C)c1N(COCC)C(=O)CCl in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) CLH report ; Proposal for Harmonized Classification and Labelling , Based on Regulation (EC) No 1272/2008 (CLP Regulation), Annex VI, Part 2, Substance Name: Acetochlor, September 2013 107-05-1 Allyl chloride C=CCCl in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Japan Chemical Industry Ecology-Toxicology & Information Center (JETOC), JAPAN; MUTAGENICITY TEST DATA OF EXISTING CHEMICAL SUBSTANCES BASED ON THE TOXICITY INVESTIGATION SYSTEM OF THE INDUSTRIAL SAFETY AND HEALTH LAW, SUPPLEMENT 3; 2005 106-94-5 1-bromopropane CCCBr in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) E.D. Barber, W.H. Donish, K.R. Mueller, A procedure for the quantitative measurement of the mutagenicity of volatile liquids in the Ames salmonella/microsome assay, Mutat Res 90 (1) (1981) 31-48. 107-20-0 Chloroacetaldehyde O=CCCl in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) RANNUG,U, GOTHE,R AND WACHTMEISTER,CA; THE MUTAGENICITY OF CHLOROETHYLENE OXIDE, CHLOROACETALDEHYDE, 2-CHLOROETHANOL AND CHLOROACETIC ACID, CONCEIVABLE METABOLITES OF VINYL CHLORIDE; CHEM. BIOL. INTERACT. 12:251-263, 1976 13909-09-6 Semustine; 1-(2-Chloroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea CC1CCC(NC(=O)N(CCCl)N=O)CC1 in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Ashby, J, et. el.; Mutagenicity to Salmonella, Drosophila and the Mouse Bone Marrow of the Human Antineoplastic Agent Fotemustine: Prediction Of Carcinogenic Potency; Mutat. Res. 286(1):101- 109, 1993 631-64-1 Dibromoacetic acid OC(=O)C(Br)Br in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) SAITO,H, ISODA,S, KATO,M AND NAGAOKA,N; MUTAGENIC ACTIVITY OF INDOOR SWIMMING POOL WATER; KANKYO HENIGEN KENKYU 17(2):169-177, 1995 79-43-6 Dichloracetic acid; Acetic acid, 2,2-dichloro- OC(=O)C(Cl)Cl in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Demarini, Dm., Perry, E. And Shelton, Ml.; Dichloroacetic Acid And Related Compounds: Induction Of Prophage In E. Coli And Mutagenicity And Mutation Spectra In Salmonella TA100; Mutagenesis 9(5):429-437, 1994 110-57-6 trans-1,4-dichloro-2-butene ClCC=CCCl in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) SHORT-TERM TEST PROGRAM SPONSORED BY THE DIVISION OF CANCER BIOLOGY, NATIONAL CANCER INSTITUTE, MS. ELLEN ZAIKA, ASSISTANT PROJECT OFFICER , p. Y91 106-89-8 Epichlorohydrin; oxirane, 2-(chloromethyl)- ClCC1CO1 in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Brams, A., et. al.; A Comparative Study, With 40 Chemicals, Of The Efficiency Of The Salmonella Assay And The SOS Chromotest (Kit Procedure); Toxicol. Lett. 38(1-2):123-133, 1987 92118-27-9 Fotemustine CCOP(=O)(C(C)NC(=O)N(CCCl)N=O)OCC in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Ashby, J, et. el.; Mutagenicity to Salmonella, Drosophila and the Mouse Bone Marrow of the Human Antineoplastic Agent Fotemustine: Prediction Of Carcinogenic Potency; Mutat. Res. 286(1):101- 109, 1993 7763-77-1 Chloroethylene oxide ClC1CO1 in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240 109-69-3 N-Butyl chloride CCCCCl in vitro Ames negative in vitro Ames negative Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 156-59-2 Cis-1,2-Dichloroethylene Cl/C=C\Cl in vitro Ames negative in vitro Ames negative Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory