CAS Chem.name Chem.SMILES #Observed Mutagenicity without S9 #Observed Mutagenicity with S9 Bioassay - Reference(s) - 137-30-4 Ziram CN(C)C(=S)S{-}.[Zn]{2+}.S{-}C(=S)N(C)C in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Hedenstedt, A., U. Rannug, C. Ramel, C. A. Wachtmeister, Mutagenicity and Metabolism Studies on 12 Thiuram and Dithiocarbamate Compounds Used as Accelerators in the Swedish Rubber Industry, Mutat. Res. 68(4), (1979), 313 – 325. 14239-68-0 Cadmium N,N-diethyldithiocarbamate CCN(CC)C(=S)S{-}.[Cd]{2+}.S{-}C(=S)N(CC)CC in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Hedenstedt, A., U. Rannug, C. Ramel, C. A. Wachtmeister, Mutagenicity and Metabolism Studies on 12 Thiuram and Dithiocarbamate Compounds Used as Accelerators in the Swedish Rubber Industry, Mutat. Res. 68(4), (1979), 313 – 325. 14324-55-1 Zinc N,N-diethyldithiocarbamate CCN(CC)C(=S)S{-}.[Zn]{2+}.S{-}C(=S)N(CC)CC in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Hedenstedt, A., U. Rannug, C. Ramel, C. A. Wachtmeister, Mutagenicity and Metabolism Studies on 12 Thiuram and Dithiocarbamate Compounds Used as Accelerators in the Swedish Rubber Industry, Mutat. Res. 68(4), (1979), 313 – 325. 137-26-8 Tetramethylthiuram disulfide (Thiram) CN(C)C(=S)SSC(=S)N(C)C in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Hedenstedt, A., U. Rannug, C. Ramel, C. A. Wachtmeister, Mutagenicity and Metabolism Studies on 12 Thiuram and Dithiocarbamate Compounds Used as Accelerators in the Swedish Rubber Industry, Mutat. Res. 68(4), (1979), 313 – 325. 137-29-1 Copper N,N-dimethyldithiocarbamate CN(C)C(=S)S{-}.[Cu]{2+}.S{-}C(=S)N(C)C in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Donner, M., K. H. Pursianen, D. Jenssen, A. Rannug, Mutagenicity of Rubber Additives and Curing Fumes. Results from Five Short-Term Bioassays, Scand. J. Work Environ. Health 9, Suppl. 2 (1983), 27 – 37. 19010-66-3 Lead N,N-dimethyldithiocarbamate CN(C)C(=S)S{-}.[Pb]{2+}.S{-}C(=S)N(C)C in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Lead Dimethyldithiocarbamate, CASRN: 19010-66-3, Testing Status, National Toxicology Program, US Dept. of Health and Human Services; http://ntp.niehs.nih.gov/?objectid=BCDDD307-123F-7908-7BA298FF200E4D20 128-04-1 Sodium dimethyldithiocarbamate CN(C)C(=S)S{-}.[Na]{+} in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) MORIYA,M OHTA,T WATANABE,K MIYAZAWA,T KATO,K AND SHIRASU,Y; FURTHER MUTAGENICITY STUDIES ON PESTICIDES IN BACTERIAL REVERSION ASSAY SYSTEMS; MUTAT. RES. 116(3-4):185-216,1982