CAS	Chem.name	Chem.SMILES	#Observed Mutagenicity without S9	#Observed Mutagenicity with S9	Bioassay - 	Reference(s) -
2438-88-2	2,3,5,6-Tetrachloro-4-Nitroanisole	COc1c(Cl)c(Cl)c(c(Cl)c1Cl)[N+]([O-])=O	in vitro Ames negative	in vitro Ames negative	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
100-14-1	P-Nitrobenzyl_Chloride	[O-][N+](=O)c1ccc(CCl)cc1	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
121-90-4	M-Nitrobenzoyl_Chloride	[O-][N+](=O)c1cccc(c1)C(Cl)=O	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
122-04-3	P-Nitrobenzoyl_Chloride	[O-][N+](=O)c1ccc(cc1)C(Cl)=O	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
1817-73-8	2-Bromo-4,6-Dinitroaniline	Nc1c(Br)cc(cc1[N+]([O-])=O)[N+]([O-])=O	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
612-23-7	O-Nitrobenzyl_Chloride	[O-][N+](=O)c1ccccc1CCl	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
619-23-8	M-Nitrobenzyl_Chloride	[O-][N+](=O)c1cccc(CCl)c1	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
70-34-8	1-Fluoro-2,4-Dinitrobenzene	[O-][N+](=O)c1ccc(F)c(c1)[N+]([O-])=O	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
88-88-0	Picryl_Chloride	[O-][N+](=O)c1cc(c(Cl)c(c1)[N+]([O-])=O)[N+]([O-])=O	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
6358-07-2	2-Amino-4-Chloro-5-Nitrophenol	Nc1cc(Cl)c(cc1O)[N+]([O-])=O	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
88-73-3	1-Chloro-2-Nitrobenzene	[O-][N+](=O)c1ccccc1Cl	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
99-30-9	2,6-Dichloro-4-Nitroaniline	Nc1c(Cl)cc(cc1Cl)[N+]([O-])=O	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
1635-61-6	5-chloro-2-nitroaniline	Nc1cc(Cl)ccc1[N+]([O-])=O	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
89-61-2	2,5-dichloronitrobenzene	[O-][N+](=O)c1cc(Cl)ccc1Cl	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	SHIMIZU M.,YASUI Y., MATSUMOTO N., MUTAT.RES. 116:217-238,1983
97-00-7	1-Chloro-2,4-dinitrobenzene	[O-][N+](=O)c1ccc(Cl)c(c1)[N+]([O-])=O	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
99-54-7	3,4-Dichloronitrobenzene	[O-][N+](=O)c1ccc(Cl)c(Cl)c1	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
100-00-5	1-Chloro-4-nitrobenzene	[O-][N+](=O)c1ccc(Cl)cc1	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	SHIMIZU M.,YASUI Y., MATSUMOTO N., MUTAT.RES. 116:217-238,1983
350-30-1	Benzene, 2-chloro-1-fluoro-4-nitro-	[O-][N+](=O)c1ccc(F)c(Cl)c1	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	SHIMIZU M.,YASUI Y., MATSUMOTO N., MUTAT.RES. 116:217-238,1983
350-46-9	1-Fluoro-4-nitrobenzene	[O-][N+](=O)c1ccc(F)cc1	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	SHIMIZU M.,YASUI Y., MATSUMOTO N., MUTAT.RES. 116:217-238,1983
364-74-9	2,5-Difluoronitrobenzene	[O-][N+](=O)c1cc(F)ccc1F	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	SHIMIZU M.,YASUI Y., MATSUMOTO N., MUTAT.RES. 116:217-238,1983
369-34-6	Benzene, 1,2-difluoro-4-nitro-	[O-][N+](=O)c1ccc(F)c(F)c1	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	SHIMIZU M.,YASUI Y., MATSUMOTO N., MUTAT.RES. 116:217-238,1983
584-48-5	1-bromo-2,4-dinitrobenzene	[O-][N+](=O)c1ccc(Br)c(c1)[N+]([O-])=O	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
611-06-3	2,4-Dichloronitrobenzene	[O-][N+](=O)c1ccc(Cl)cc1Cl	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	SHIMIZU M.,YASUI Y., MATSUMOTO N., MUTAT.RES. 116:217-238,1983
709-49-9	1-iodo-2,4-dinitrobenzene	[O-][N+](=O)c1ccc(I)c(c1)[N+]([O-])=O	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	GUPTA,RL, SAINI,BHK AND JUNEJA,TR;  MUTAT. RES. 381(1):41-47, 1997
17700-09-3	Benzene, 4-nitro-1,2,3-trichloro-	[O-][N+](=O)c1ccc(Cl)c(Cl)c1Cl	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	SHIMIZU M.,YASUI Y., MATSUMOTO N., MUTAT.RES. 116:217-238,1983
456-27-9	Benzenediazonium,_4-nitro-,_tetrafluoroborate(1-)	F[B-](F)(F)F.[O-][N+](=O)c1ccc(cc1)[N+]#N	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	MERSCH-SUNDERMANN,V AND KRAEMER,H;  ZENTRALBL. HYG. UMWELTMED. 193(5):471-480, 1993
62625-14-3	Phenol, 2-amino-6-chloro-4-nitro-, hydrochloride (1:1)	[Cl-].[N+H3]c1cc(cc(Cl)c1O)[N+]([O-])=O	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
7227-92-1	1-(4-Nitrophenyl)-3,3-dimethyltriazene	CN(C)N=Nc1ccc(cc1)[N+]([O-])=O	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Cerna, M., Lepsi, P., Rossner, P. and Pohlova, H.; Mutagenicity of Some Substituted 1-Phenyl-3,3-Dimethyltriazenes. I. The Salmonella/Mammalian Microsome Assay and Repair Test; Mutat. Res. 190(3):177-182, 1987
89-63-4	4-Chloro-2-Nitroaniline	Nc1ccc(Cl)cc1[N+]([O-])=O	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
117-18-0	2,3,5,6-Tetrachloronitrobenzene	[O-][N+](=O)c1c(Cl)c(Cl)cc(Cl)c1Cl	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
3209-22-1	2,3-Dichloronitrobenzene	[O-][N+](=O)c1cccc(Cl)c1Cl	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	NIHS Japan
50-65-7	Niclosamide	Oc1ccc(Cl)cc1C(=O)Nc1ccc(cc1Cl)[N+]([O-])=O	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	ESPINOSA-AGUIRRE,JJ, SANTOS,JR AND DE NAVA,CC; INFLUENCE OF THE UVR REPAIR SYSTEM ON THE MUTAGENCIITY OF ANTIPARASITIC DRUGS; MUTAT. RES. 222(3):161-166, 1989
13301-61-6	c.i. disperse orange 37; propanenitrile, 3-[[4-[(2,6-dichloro-4-nitrophenyl)azo]phenyl]ethylamino]-;	CCN(CCC#N)c1ccc(cc1)N=Nc1c(Cl)cc(cc1Cl)[N+]([O-])=O	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	de Aragao Umbuzeiro, G., Freeman, H.S., Warren, S.H., de Oliveira, D.P., Terao, Y., Watanabe, T., Claxton, L.D., The contribution of azo dyes to the mutagenic activity of the Cristais River. Chemosphere, 2005, 60(1), 55-64.
14097-03-1	c.i. basic red 18; ethanaminium, 2-[[4-[(2-chloro-4-nitrophenyl)azo]phenyl]ethylamino]-n,n,n-trimethyl-	CCN(CC[N+](C)(C)C)c1ccc(cc1)N=Nc1ccc(cc1Cl)[N+]([O-])=O	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Helmes, C.T., Sigman, C.C., Fung, V.A., Thompson, K., Doeltz, M.K., Mackie, M., Klein, T.E., Lent, D., A study of azo and nitro dyes for the selection of candidates for carcinogen bioassay. J. Environ. Sci. Health A Environ. Sci. Eng., 1984, 19(2), 97-231.
51868-46-3	c.i. disperse blue 373; acetamide, n-[2-[(2-bromo-4,6-dinitrophenyl)azo]-5-(di-2-propenylamino)-4-methoxyphenyl]-	COc1cc(N=Nc2c(Br)cc(cc2[N+]([O-])=O)[N+]([O-])=O)c(NC(C)=O)cc1N(CC=C)CC=C	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	de Aragao Umbuzeiro, G., Freeman, H.S., Warren, S.H., de Oliveira, D.P., Terao, Y., Watanabe, T., Claxton, L.D., The contribution of azo dyes to the mutagenic activity of the Cristais River. Chemosphere, 2005, 60(1), 55-64.
56548-64-2	2-[(2-bromo-4,6-dinitrophenyl)azo]-5-(diethylamino)-4-methoxyacetanilde	CCN(CC)c1cc(NC(C)=O)c(cc1OC)N=Nc1c(Br)cc(cc1[N+]([O-])=O)[N+]([O-])=O	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	de Aragao Umbuzeiro, G., Freeman, H., Warren, S.H., Kummrow, F., Claxton, L.D., Mutagenicity evaluation of the commercial product CI Disperse Blue 291 using different protocols of the Salmonella assay. Food Chem. Toxicol., 2005, 43(1), 49-56.
6486-23-3	butanamide, 2-[(4-chloro-2-nitrophenyl)azo]-n-(2-chlorophenyl)-3-oxo-; 2-[(4-chloro-2-nitrophenyl)azo]-n-(2-chlorophenyl)-3-oxobutyramide	CC(=O)C(N=Nc1ccc(Cl)cc1[N+]([O-])=O)C(=O)Nc1ccccc1Cl	in vitro Ames negative	in vitro Ames negative	Bacterial Reverse Mutation Assay (e.g. Ames Test)	2-[(4-Chloro-2-nitrophenyl)azo]-N-(2-chlorophenyl)-3-oxobutyramide, CAS No 6486-23-3. ECHA Legal notice, Registration dossier. http://echa.europa.eu/registration-dossier/-/registered-dossier/13178
12236-62-3	butanamide, 2-[(4-chloro-2-nitrophenyl)azo]-n-(2,3-dihydro-2-oxo-1h-benzimidazol-5-yl)-3-oxo-	CC(=O)C(N=Nc1ccc(Cl)cc1[N+]([O-])=O)C(=O)Nc1ccc2NC(=O)Nc2c1	in vitro Ames negative	in vitro Ames negative	Bacterial Reverse Mutation Assay (e.g. Ames Test)	2-[(4-Chloro-2-nitrophenyl)azo]-N-(2,3-dihydro-2-oxo-1H-benzimidazol-5-yl)-3-oxobutyramide, CAS No 12236-62-3. ECHA Legal notice, Registration dossier. http://echa.europa.eu/registration-dossier/-/registered-dossier/14130
13515-40-7	butanamide, 2-[(4-chloro-2-nitrophenyl)azo]-n-(2-methoxyphenyl)-3-oxo-; 2-[(4-chloro-2-nitrophenyl)azo]-n-(2-methoxyphenyl)-3-oxobutyramide	COc1ccccc1NC(=O)C(N=Nc1ccc(Cl)cc1[N+]([O-])=O)C(C)=O	in vitro Ames negative	in vitro Ames negative	Bacterial Reverse Mutation Assay (e.g. Ames Test)	2-[(4-chloro-2-nitrophenyl)azo]-N-(2-methoxyphenyl)-3-oxobutyramide, CAS No 13515-40-7. ECHA Legal notice, Registration dossier. http://echa.europa.eu/registration-dossier/-/registered-dossier/11102
23355-64-8	c.i. disperse brown 1	OCCN(CCO)c1ccc(N=Nc2c(Cl)cc(cc2Cl)[N+]([O-])=O)c(Cl)c1	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Seifried, H.E., Seifried, R.M., Clarke, J.J., Junghans, T.B., San, R.H., A compilation of two decades of mutagenicity test results with the Ames Salmonella typhimurium and L5178Y mouse lymphoma cell mutation assays. Chem. Res. Toxicol., 2006, 19(5), 627-644.