CAS Chem.name Chem.SMILES #Observed Mutagenicity without S9 #Observed Mutagenicity with S9 Bioassay - Reference(s) - 127502-68-5 3-Isopropyl-4-Nitro-Biphenyl CC(C)c1cc(ccc1[N+]([O-])=O)-c1ccccc1 in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 275795-12-5 3,5-Diethyl-4-Nitro-Biphenyl CCc1cc(cc(CC)c1[N+]([O-])=O)-c1ccccc1 in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 10125-76-5 4-Nitrosobiphenyl O=Nc1ccc(cc1)-c1ccccc1 in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25 6810-26-0 Hydroxylamine, N-4-Biphenylyl- ONc1ccc(cc1)-c1ccccc1 in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25 92-93-3 4-Nitro-Biphenyl [O-][N+](=O)c1ccc(cc1)-c1ccccc1 in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25 92814-28-3 4-Ethyl-3-Nitrobiphenyl CCc1cc(ccc1[N+]([O-])=O)-c1ccccc1 in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25 70634-28-5 1,1'-Biphenyl, 3-(1,1-Dimethylethyl)-4-Nitro- CC(C)(C)c1cc(ccc1[N+]([O-])=O)-c1ccccc1 in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25 275795-16-9 1,1'-Biphenyl, 3-(1,1-Dimethylethyl)-4-Nitroso- CC(C)(C)c1cc(ccc1N=O)-c1ccccc1 in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 279242-09-0 1,1'-Biphenyl, 4-Ethyl-4'-Nitro- CCc1ccc(cc1)-c1ccc(cc1)[N+]([O-])=O in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 279242-11-4 1,1'-Biphenyl, 4-(1,1-Dimethylethyl)-4'-Nitro- CC(C)(C)c1ccc(cc1)-c1ccc(cc1)[N+]([O-])=O in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 279242-17-0 1,1'-Biphenyl, 4-(1,1-Dimethylethyl)-4'-Nitroso- CC(C)(C)c1ccc(cc1)-c1ccc(cc1)N=O in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 952-21-6 1,1'-Biphenyl, 3-Methyl-4'-Nitro- Cc1cccc(c1)-c1ccc(cc1)[N+]([O-])=O in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25 345667-01-8 [1,1'-Biphenyl]-4-Amine, 3-(1,1-Dimethylethyl)-N-Hydroxy- CC(C)(C)c1cc(ccc1NO)-c1ccccc1 in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 345667-02-9 [1,1'-Biphenyl]-4-Amine, 4'-(1,1-Dimethylethyl)-N-Hydroxy- CC(C)(C)c1ccc(cc1)-c1ccc(NO)cc1 in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 119-90-4 3,3'-Dimethoxybenzidine COc1cc(ccc1N)-c1ccc(N)c(OC)c1 in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) TAKAHASHI,A AND ONO,H; MUTAGENICITY ASSESSMENT IN 44 EPOXY RESIN HARDENERS IN SALMONELLA TYPHIMURIUM TESTER STRAINS; CHEM. EXPRESS 8(9):785-788, 1993 1211-40-1 4-Amino-4'-Nitrobiphenyl Nc1ccc(cc1)-c1ccc(cc1)[N+]([O-])=O in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) SINSHEIMER,JE, HOOBERMAN,BH, DAS,SK, BREZZELL,MD AND YOU,Z; THE IN VIVO AND IN VITRO GENOTOXICITY OF AROMATIC AMINES IN RELATIONSHIP TO THE GENOTOXICITY OF BENZIDINE; MUTAT. RES. 268(2):255-264, 1992 133561-39-4 2,4'-Diamino-2,'4-Dinitrobiphenyl Nc1ccc(-c2ccc(cc2N)[N+]([O-])=O)c(c1)[N+]([O-])=O in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) HIRAYAMA,T, IGUCHI,K, YAMANAKA,Y, ISHIHARA,M, SHINYA,M, TAKAHASHI,K AND WATANABE,T; STUDIES ON THE STRUCTURE ELUCIDATION OF MUTAGENIC METABOLITES OF 2,4-DINITROBIPHENYL DERIVATIVES AGAINST SALMONELLA TYPHIMURIUM TA98; EISEI KAGAKU 37(3):229-238, 1991 3365-85-3 P,P'-Diaminoterphenyl Nc1ccc(cc1)-c1ccc(cc1)-c1ccc(N)cc1 in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) WUEBBLES,BJY AND FELTON,JS; EVALUATION OF LASER DYE MUTAGENICITY USING THE AMES/ SALMONELLA MICROSOME TEST; ENVIRON. MUTAGEN. 7(4):511-522, 1985 448-97-5 3,3'-Difluorobenzidine Nc1ccc(cc1F)-c1ccc(N)c(F)c1 in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) SAVARD,S AND JOSEPHY,PD; SYNTHESIS AND MUTAGENICITY OF 3,3'-DIHALOGENATED BENZIDINES; CARCINOGENESIS 7(7):1239-1241, 1986 61841-39-2 3-Nitrobenzidine Nc1ccc(cc1)-c1ccc(N)c(c1)[N+]([O-])=O in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) YOU,Z, BREZZELL,MD, DAS,SK, ESPADAS-TORRE,MC, HOOBERMAN,BH AND SINSHEIMER,JE; ORTHO-SUBSTITUENT EFFECTS ON THE IN VITRO AND IN VIVO GENOTOXICITY OF BENZIDINE DERIVATIVES; MUTAT. RES. 319(1):19-30, 1993 63390-12-5 3,3',5-Trichlorobenzidine Nc1ccc(cc1Cl)-c1cc(Cl)c(N)c(Cl)c1 in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) JOSEPHY,PD AND WILLIAMS,LL; UNAMBIGUOUS SYNTHESIS OF ASYMMETRICALLY SUBSTITUTED CHLORINATED BENZIDINES, AND A STUDY OF THEIR MUTAGENICITY IN THE AMES TEST. POTENT ACTIVITY OF 3,5,3'-TRICHLOROBENZIDINE; MUTAGENESIS 2(3):225-228, 1987 389104-60-3 Biphenyl, 3-ethyl-4-amino- CCc1cc(ccc1N)-c1ccccc1 in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 612-83-9 3,3'-Dichlorobenzidine dihydrochloride Cl.Cl.Nc1ccc(cc1Cl)-c1ccc(N)c(Cl)c1 in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 91-93-0 3,3'-Dimethoxybenzidine-4,4'-Diisocyanate COc1cc(ccc1N=C=O)-c1ccc(N=C=O)c(OC)c1 in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 92-67-1 4-Amino-1,1'-Biphenyl; Biphenyl-4-ylamine Nc1ccc(cc1)-c1ccccc1 in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 119-93-7 3,3'-Tolidine Cc1cc(ccc1N)-c1ccc(N)c(C)c1 in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 2143-88-6 4-Methyl-4'-Nitrobiphenyl Cc1ccc(cc1)-c1ccc(cc1)[N+]([O-])=O in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 6459-94-5 C.I. Acid Red 114 Cc1ccc(cc1)S(=O)(=O)Oc1ccc(cc1)N=Nc1ccc(cc1C)-c1ccc(N=Nc2c(O)ccc3cc(cc(c23)S(O)(=O)=O)S(O)(=O)=O)c(C)c1 in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 54810-82-1 3,5-Dimethyl-4-Aminobiphenyl Cc1cc(cc(C)c1N)-c1ccccc1 in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 127502-69-6 3-Isopropyl-4-Aminobiphenyl; 3-Isopropyl-biphenyl-4-ylamine CC(C)c1cc(ccc1N)-c1ccccc1 in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 275795-17-0 3-tert-Butyl-4-Aminobiphenyl; 3-tert-Butyl-biphenyl-4-ylamine CC(C)(C)c1cc(ccc1N)-c1ccccc1 in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 279242-10-3 1,1'-Biphenyl, 4-(1-Methylethyl)-4'-Nitro- CC(C)c1ccc(cc1)-c1ccc(cc1)[N+]([O-])=O in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 279242-12-5 1,1'-Biphenyl, 4-Butyl-4'-Nitro- CCCCc1ccc(cc1)-c1ccc(cc1)[N+]([O-])=O in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 279242-14-7 1,1'-Biphenyl, 3,5-Dimethyl-4'-Nitro- Cc1cc(C)cc(c1)-c1ccc(cc1)[N+]([O-])=O in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 389104-61-4 3-Butyl-biphenyl-4-ylamine; Biphenyl, 3-butyl-4-amino- CCCCc1cc(ccc1N)-c1ccccc1 in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) GLENDE,C. et al; TRANSFORMATION OF MUTAGENIC AROMATIC AMINES INTO NON-MUTAGENIC SPECIES BY ALKYL SUBSTITUENTS. PART I. ALKYLATION ORTHO TO THE AMINO FUNCTION. MUTAT. RES. 498(1-2):19-37, 2001 91-97-4 3,3'-Dimethyl-4,4'-diphenylene diisocyanate; Bitolylene diisocyanate Cc1cc(ccc1N=C=O)-c1ccc(N=C=O)c(C)c1 in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 4463-22-3 N-Hydroxy-4-acetylaminobiphenyl CC(=O)N(O)c1ccc(cc1)-c1ccccc1 in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) WANG,CY, LINSMAIER-BEDNAR,EM, LEE,MS AND KING,CM; MUTAGENICITIES OF N-ACYL-N-ARYLHYDROXYLAMINES FOR SALMONELLA; CHEM-BIOL. INTERACT. 67(3-4):215-223, 1988 91-95-2 3,3'-Diaminobenzidine Nc1ccc(cc1N)-c1ccc(N)c(N)c1 in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Chung,K. et al; Mutagenicity Studies Of Benzidine And Its Analogs: Structure-Activity Relationships; Toxicol. Sci. 56(2):351-356, 2000; Messerly, Ea. et al; Structure-Mutagenicity Relationship Of Benzidine Analogues; Environ. Mol. Mutagen. 10:263-274, 1987 1204-41-7 4-Biphenylamine, 2'-methyl- Cc1ccccc1-c1ccc(N)cc1 in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) SINSHEIMER,JE. Et al; THE IN VIVO AND IN VITRO GENOTOXICITY OF AROMATIC AMINES IN RELATIONSHIP TO THE GENOTOXICITY OF BENZIDINE; MUTAT. RES. 268(2):255-264, 1992 15403-45-9 3,3'-Dicarbomethoxybenzidine COC(=O)c1cc(ccc1N)-c1ccc(N)c(c1)C(=O)OC in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) YOU,Z. et al; ORTHO-SUBSTITUENT EFFECTS ON THE IN VITRO AND IN VIVO GENOTOXICITY OF BENZIDINE DERIVATIVES; MUTAT. RES. 319(1):19-30, 1993 3366-61-8 N-Acetylbenzidine CC(=O)Nc1ccc(cc1)-c1ccc(N)cc1 in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) MAKENA,PS AND CHUNGK-T; EVIDENCE THAT 4-AMINOBIPHENYL, BENZIDINE, AND BENZIDINE CONGENERS PRODUCE GENOTOXICITY THROUGH REACTIVE OXYGEN SPECIES; ENVIRON. MOL. MUTAGEN. 48(5):404-413, 2007 314-13-6 Evans blue Cc1cc(ccc1N=Nc1ccc2c(cc(c(N)c2c1O)S(O)(=O)=O)S(O)(=O)=O)-c1ccc(N=Nc2ccc3c(cc(c(N)c3c2O)S(O)(=O)=O)S(O)(=O)=O)c(C)c1 in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Robertson J., et al., Carcinogenesis, 3(1), 21-25, 1982 531-85-1 Benzidine dihydrochloride Cl.Cl.Nc1ccc(cc1)-c1ccc(N)cc1 in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 3626-28-6 C.I. Direct green 1 [Na+].[Na+].Nc1c(N=Nc2ccc(cc2)-c2ccc(cc2)N=Nc2ccc(O)cc2)c(cc2cc(c(N=Nc3ccccc3)c(O)c12)S([O-])(=O)=O)S([O-])(=O)=O in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 1937-37-7 C.I. Direct Black 38 [Na+].[Na+].Nc1ccc(N=Nc2ccc(cc2)-c2ccc(cc2)N=Nc2c(N)c3c(O)c(N=Nc4ccccc4)c(cc3cc2S([O-])(=O)=O)S([O-])(=O)=O)c(N)c1 in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 135-68-2 4-Amino-4'-chlorodiphenyl Nc1ccc(cc1)-c1ccc(Cl)cc1 in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Sinsheimer,JE, Hooberman,BH, DAS,SK, BREZZELL,MD AND YOU,Z; THE IN VIVO AND IN VITRO GENOTOXICITY OF AROMATIC AMINES IN RELATIONSHIP TO THE GENOTOXICITY OF BENZIDINE; MUTAT. RES. 268(2):255-264, 1992 92-87-5 benzidine;biphenyl-4,4'-diamine Nc1ccc(cc1)-c1ccc(N)cc1 in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) MESSERLY,EA, FEKETE,JE, WADE,DR AND SINSHEIMER,JE; STRUCTURE-MUTAGENICITY RELATIONSHIP OF BENZIDINE ANALOGUES; ENVIRON. MOL. MUTAGEN. 10:263-274, 1987; SINSHEIMER,JE, HOOBERMAN,BH, DAS,SK, BREZZELL,MD AND YOU,Z; THE IN VIVO AND IN VITRO GENOTOXICITY OF AROMATIC AMINES IN RELATIONSHIP TO THE GENOTOXICITY OF BENZIDINE; MUTAT. RES. 268(2):255-264, 1992 573-58-0 c.i. direct red 28;congo red; [Na+].[Na+].Nc1c(cc(c2ccccc12)S([O-])(=O)=O)N=Nc1ccc(cc1)-c1ccc(cc1)N=Nc1cc(c2ccccc2c1N)S([O-])(=O)=O in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Zhou,Y, You,X and Ye,X; MUTAGENICITY OF BENZIDINES AND THEIR CONGENER DERIVATIVE DYES; HUANJING KEXUE 8(2):31-34, 1987 613-35-4 n,n-diacetylbenzidine CC(=O)Nc1ccc(cc1)-c1ccc(NC(C)=O)cc1 in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) MAKENA,PS AND CHUNGK-T; EVIDENCE THAT 4-AMINOBIPHENYL, BENZIDINE, AND BENZIDINE CONGENERS PRODUCE GENOTOXICITY THROUGH REACTIVE OXYGEN SPECIES; ENVIRON. MOL. MUTAGEN. 48(5):404-413, 2007 34237-98-4 3,3'-dibromobenzidine Nc1ccc(cc1Br)-c1ccc(N)c(Br)c1 in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) SAVARD,S AND JOSEPHY,PD; SYNTHESIS AND MUTAGENICITY OF 3,3'-DIHALOGENATED BENZIDINES; CARCINOGENESIS 7(7):1239-1241, 1986 91-94-1 3,3'-dichlorobenzidine; [1,1'-biphenyl]-4,4'-diamine, 3,3'-dichloro- Nc1ccc(cc1Cl)-c1ccc(N)c(Cl)c1 in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) GARNER,RC, WALPOLE,AL AND ROSE,FL; TESTING OF SOME BENZIDINE ANALOGUES FOR MICROSOMAL ACTIVATION TO BACTERIAL MUTAGENS; CANCER LETT. 1:39-42, 1975][COMMONER,B; RELIABILITY OF BACTERIAL MUTAGENESIS TECHNIQUES TO DISTINGUISH CARCINOGENIC AND NONCARCINOGENIC CHEMICALS;NTIS PB-259934, EPA-600/1-76-022, 1976 6271-79-0 3,3'-dinitrobenzidine;3,3'-dinitro[1,1'-biphenyl]-4,4'-diamine Nc1ccc(cc1[N+]([O-])=O)-c1ccc(N)c(c1)[N+]([O-])=O in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) You,Z, Brezzell,Md, Das,Sk, ESPADAS-TORRE,MC, HOOBERMAN,BH AND SINSHEIMER,JE; ORTHO-SUBSTITUENT EFFECTS ON THE IN VITRO AND IN VIVO GENOTOXICITY OF BENZIDINE DERIVATIVES; MUTAT. RES. 319(1):19-30, 1993 2243-78-9 2-nitrobenzidine Nc1ccc(cc1)-c1ccc(N)cc1[N+]([O-])=O in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) You,Z, Brezzell,Md, Das,Sk, ESPADAS-TORRE,MC, HOOBERMAN,BH AND SINSHEIMER,JE; ORTHO-SUBSTITUENT EFFECTS ON THE IN VITRO AND IN VIVO GENOTOXICITY OF BENZIDINE DERIVATIVES; MUTAT. RES. 319(1):19-30, 1993 16071-86-6 C.I. Direct brown 95 [Na+].[Na+].[Cu+2].Oc1ccc(cc1C([O-])=O)N=Nc1ccc(cc1)-c1ccc(cc1)N=Nc1c(O)ccc(N=Nc2cc(ccc2[O-])S([O-])(=O)=O)c1[O-] in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Zhou,Y, You,X and Ye,X; MUTAGENICITY OF BENZIDINES AND THEIR CONGENER DERIVATIVE DYES; HUANJING KEXUE 8(2):31-34, 1987 72-57-1 C.I. Direct blue 14 [Na+].[Na+].[Na+].[Na+].Cc1cc(ccc1N=Nc1c(O)c2c(N)cc(cc2cc1S([O-])(=O)=O)S([O-])(=O)=O)-c1ccc(N=Nc2c(O)c3c(N)cc(cc3cc2S([O-])(=O)=O)S([O-])(=O)=O)c(C)c1 in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Cancer Institute 54827-17-7 3,3',5,5'-Tetramethylbenzidine Cc1cc(cc(C)c1N)-c1cc(C)c(N)c(C)c1 in vitro Ames negative in vitro Ames negative Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory