CAS	Chem.name	Chem.SMILES	#Observed Mutagenicity without S9	#Observed Mutagenicity with S9	Bioassay - 	Reference(s) -
78-87-5	1,2-Dichloro-propane	CC(Cl)CCl	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	U.S.Environmental Protection Agency Gene-Tox Program. Mutation Research, 168, (1996) pp. 69-240
21739-91-3	Cytembena	COc1ccc(C(=O)C(Br)=CC(O)=O)cc1	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
542-75-6	1,3-Dichloropropene; 1-Propene, 1,3-Dichloro	ClCC=CCl	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
616-23-9	2,3-Dichloro-1-Propanol	OCC(Cl)CCl	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
78-88-6	2,3-Dichloro-1-Propene	C=C(Cl)CCl	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	U.S.Environmental Protection Agency Gene-Tox Program. Mutation Research, 168, (1996) pp. 69-240
55965-84-9	Kathon 886	CN1C(=O)C=C(Cl)S1_CN1C(=O)C=CS1	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Connor, TH., Tee, PG., Afshar, M. and Connor, KM.; Mutagenicity of Cosmetic Products Containing Kathon; Environ. Mol. Mutagen. 28(2):127-132, 1996
87619-82-7	s-(1,2,3,4,4-pentachloro-1,3-butadienyl)-l-cysteine	NC(CSC(Cl)=C(Cl)C(Cl)=C(Cl)Cl)C(O)=O	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
115453-72-0	s-(1,2,3,3,3-pentachloroprop-1-enyl)-l-cysteine	NC(CSC(Cl)=C(Cl)C(Cl)(Cl)Cl)C(O)=O	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	VAMVAKAS,S, BERTHOLD,K, DEKANT,W AND HENSCHLER,D; CHEM.BIOL. INTERACT. 65(1):5971, 1988
77439-76-0	3-chloro-4-(dichloromethyl)-5-hydroxy-2(5h)-furanone;mx;3-chloro-4-dichloromethyl-5-hydroxy-2-furanone	OC1C(C(Cl)Cl)=C(Cl)C(=O)O1	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
766-40-5	3,4-dichloro-5-hydroxy-2(5h)-furanone;3,4-dichloro-5-hydroxyfuran-2(5h)-one	OC1C(Cl)=C(Cl)C(=O)O1	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
112309-61-2	3-chloro-4-methyl-5-hydroxy-2(5h)-furanone;3-chloro-4-methyl-5-hydroxy-2(5h)­furanone (mcf)	CC1C(O)OC(=O)C=1Cl	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	LALONDE,RT, COOK,GP, PERAKYLA,H AND BU,L, CHEM. RES. TOXICOL. 4(5):540545, 1991; SHAUGHNESSY,DT OHE,T LANDI,S WARREN,SH RICHARD,AM MUNTER,T FRANZEN,R KRONBERG,L AND DEMARINI,DM; ENVIRON. MOL. MUTAGEN. 35(2):106113, 2000
31555-54-1	3,4-dichloro-5-dichloromethylene-2-furanone	O=C1C(Cl)=C(Cl)C(=C(Cl)Cl)O1	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
97055-38-4	3-chloro-4-(dichloromethyl)-5-methoxy-2(5h)-furanone	COC1C(C(Cl)Cl)=C(Cl)C(=O)O1	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
112654-68-9	3-chloro-5-dichloromethylene-2-furanone	O=C1C(Cl)=CC(=C(Cl)Cl)O1	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	SMEDS,A, FRANZEN,R AND KRONBERG,L; ENVIRON. SCI. TECHNOL. 29(9):18391844, 1995
122551-89-7	3-chloro-4-(dichloromethyl)-2(5h)-furanone;3-chloro-4-(dichloromethyl)-2-(5h)-furanone	O=C1C(Cl)=C(C(Cl)Cl)CO1	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	LALONDE,RT, COOK,GP, PERAKYLA,H, DENCE,CW AND BABISH,JG; ENVIRON. MOL. MUTAGEN. 17(1):4048, 1991; KRONBERG,L, CHRISTMAN,RF, SINGH,R, AND BALL,LM; ENVIRON. SCI. TECHNOL. 25(1):99104, 1991
125974-01-8	3-chloro-4-(chloromethyl)-2(5h)-furanone	O=C1C(Cl)=C(CCl)CO1	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	LALONDE,RT, COOK,GP, PERAKYLA,H AND BU,L,  CHEM. RES. TOXICOL. 4(5):540545, 1991; LALONDE,RT, BU,L, HENWOOD,A, FIUMANO,J AND ZHANG,L; CHEM. RES. TOXICOL. 10(12):14271436, 1997
125974-08-5	3-chloro-4-(chloromethyl)-5-hydroxy-2(5h)-furanone	OC1C(CCl)=C(Cl)C(=O)O1	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	LALONDE,RT, COOK,GP, PERAKYLA,H AND BU,L,  CHEM. RES. TOXICOL. 4(5):540545, 1991; LALONDE,RT, BU,L, HENWOOD,A, FIUMANO,J AND ZHANG,L; CHEM. RES. TOXICOL. 10(12):14271436, 1997; NIITTYKOSKI,M, HYTTINEN,JMT AND JANSSON,K; MUTAT. RES. 348(1):5155, 1995
132059-51-9	3-chloro-4-(bromochloromethyl)-5-hydroxy-2(5h)-furanone	OC1C(C(Cl)Br)=C(Cl)C(=O)O1	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	SUZUKI,N AND MATSUO,T; J. FAC. ENG. UNIV. TOKYO, SER.B 42(4):307315, 1994; RAMOS,I LLOVERAS,M SOLANS,X HUICI,A AND MESSEGUER,A; ENVIRON. TOXICOL. CHEM. 19(11):26312636, 2000; RAMOS,I LLOVERAS,M SOLANS,X HUICI,A AND MESSEGUER,A; ENVIRON. TOXICOL. CHEM. 19(11):26312636, 2000
132059-52-0	3-chloro-4-(dibromomethyl)-5-hydroxy-2(5h)-furanone	OC1C(C(Br)Br)=C(Cl)C(=O)O1	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	SUZUKI,N AND MATSUO,T; J. FAC. ENG. UNIV. TOKYO, SER.B 42(4):307315, 1994; LALONDE,RT, BU,L, HENWOOD,A, FIUMANO,J AND ZHANG,L;CHEM. RES. TOXICOL. 10(12):14271436, 1997; RAMOS,I LLOVERAS,M SOLANS,X HUICI,A AND MESSEGUER,A; ENVIRON. TOXICOL. CHEM. 19(11):26312636, 2000
132059-53-1	3-bromo-4-(dibromomethyl)-5-hydroxy-2(5h)-furanone	OC1C(C(Br)Br)=C(Br)C(=O)O1	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	SUZUKI,N AND MATSUO,T; J. FAC. ENG. UNIV. TOKYO, SER.B 42(4):307315, 1994; LALONDE,RT, BU,L, HENWOOD,A, FIUMANO,J AND ZHANG,L;CHEM. RES. TOXICOL. 10(12):14271436, 1997; RAMOS,I LLOVERAS,M SOLANS,X HUICI,A AND MESSEGUER,A; ENVIRON. TOXICOL. CHEM. 19(11):26312636, 2000
149418-41-7	3,4-dibromo-2(5h)-furanone	O=C1C(Br)=C(Br)CO1	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	LALONDE,RT AND LEO,HR; CHEM. RES. TOXICOL. 7(6):779783, 1994
199536-62-4	3-bromo-4-(bromomethyl)-2(5h)-furanone	O=C1C(Br)=C(CBr)CO1	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	LALONDE,RT, BU,L, HENWOOD,A, FIUMANO,J AND ZHANG,L;CHEM. RES. TOXICOL. 10(12):14271436, 1997
199536-64-6	3-bromo-4-(bromomethyl)-5-hydroxy-2(5h)-furanone	OC1C(CBr)=C(Br)C(=O)O1	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	LALONDE,RT, BU,L, HENWOOD,A, FIUMANO,J AND ZHANG,L;CHEM. RES. TOXICOL. 10(12):14271436, 1997
199536-65-7	3-chloro-4-(bromomethyl)-2(5h)-furanone	O=C1C(Cl)=C(CBr)CO1	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	LALONDE,RT, BU,L, HENWOOD,A, FIUMANO,J AND ZHANG,L; CHEM. RES. TOXICOL. 10(12):14271436, 1997
199536-79-3	3-bromo-4-(dibromomethyl)-2(5h)-furanone	O=C1C(Br)=C(C(Br)Br)CO1	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	LALONDE,RT, BU,L, HENWOOD,A, FIUMANO,J AND ZHANG,L; CHEM. RES. TOXICOL. 10(12):14271436, 1997
199536-82-8	3-chloro-4-(dibromomethyl)-2(5h)-furanone	O=C1C(Cl)=C(C(Br)Br)CO1	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	LALONDE,RT, BU,L, HENWOOD,A, FIUMANO,J AND ZHANG,L; CHEM. RES. TOXICOL. 10(12):14271436, 1997
199536-84-0	3-bromo-4-(chloromethyl)-2(5h)-furanone	O=C1C(Br)=C(CCl)CO1	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	LALONDE,RT, BU,L, HENWOOD,A, FIUMANO,J AND ZHANG,L; CHEM. RES. TOXICOL. 10(12):14271436, 1997
87-68-3	Hexachloro-1,3-butadiene	ClC(Cl)=C(Cl)C(Cl)=C(Cl)Cl	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
96-18-4	1,2,3-Trichloropropane	ClCC(Cl)CCl	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
3234-02-4	Trans-2,3-Dibromo-2-Butene-1,4-Diol	OCC(Br)=C(Br)CO	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
920-37-6	2-Chloroacrylonitrile	C=C(Cl)C#N	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Eder, E., C. Deininger, E. Weinfurtner, Genotoxicity of 2-Halosubstituted Enals and 2-Chloroacrylonitrile in the Ames Test and the SOS Chromotest, Mutat. Res. 322 (1994), 321 – 328
2303-16-4	Diallate; Carbamic acid, diisopropylthio-, S-(2,3-dichloroallyl) ester	CC(C)N(C(C)C)C(=O)SCC(Cl)=CCl	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	SANDHU,SS, WATERS,MD, MORTELMANS,KE, EVANS,EL, JOTZ,MM, MITCHELL,AD AND KASICA, V; EVALUATION OF DIALLATE AND TRIALLATE HERBICIDES FOR GENOTOXIC EFFECTS IN A BATTERY OF IN VITRO AND SHORT-TERM IN VIVO TESTS; MUTAT. RES. 136(6):173-183, 1984
13171-21-6	phosphamidon	CCN(CC)C(=O)C(Cl)=C(C)OP(=O)(OC)OC	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	VISHWANATH,R AND JAMIL,K; MUTAGENIC AND GENOTOXIC ACTIVITIES OF CERTAIN ORGANOPHOSPHORUS COMPOUNDS, USING AMES SALMONELLA ASSAY, WITH AND WITHOUT MICROSOMAL INDUCTION; INDIAN J. EXP. BIOL. 24(5):305-308, 1986
2303-17-5	Tri-allate	CC(C)N(C(C)C)C(=O)SCC(Cl)=C(Cl)Cl	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	De Lorenzo, F., Staiano, N., Silengo, L., Cortese, R., Mutagenicity of Diallate, Sulfallate, and Triallate and Relationship Between Structure and Mutagenic Effects of Carbamates Used Widely in Agriculture. Cancer Res., 1978, 38(1), 13 – 15