CAS	Chem.name	Chem.SMILES	#Observed Mutagenicity without S9	#Observed Mutagenicity with S9	Bioassay - 	Reference(s) -
188107-70-2	9-Methyl-2-Nitrocarbazole	Cn1c2ccccc2c2ccc(cc12)[N+]([O-])=O	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
16238-56-5	7-Bromomethyl-12-Methylbenz(A)Anthracene	Cc1c2ccccc2c(CBr)c2ccc3ccccc3c12	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
42397-64-8	1,6-Dinitropyrene	[O-][N+](=O)c1ccc2ccc3c(ccc4ccc1c2c34)[N+]([O-])=O	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
42397-65-9	1,8-Dinitropyrene	[O-][N+](=O)c1ccc2ccc3ccc(c4ccc1c2c34)[N+]([O-])=O	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
128714-75-0	1,6-Dinitrobenzo(a)pyrene	[O-][N+](=O)c1ccc2ccc3c(c4ccccc4c4ccc1c2c34)[N+]([O-])=O	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
128714-76-1	3,6-Dinitrobenzo(a)pyrene	[O-][N+](=O)c1ccc2ccc3c4ccccc4c(c4ccc1c2c34)[N+]([O-])=O	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
57-97-6	7,12-Dimethylbenz(A)Anthracene	Cc1c2ccccc2c(C)c2ccc3ccccc3c12	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
95331-48-9	Acetamide, N-hydroxy-N-1-pyrenyl-	CC(=O)N(O)c1ccc2ccc3cccc4ccc1c2c34	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Ball, LM, Kohan, MJ, Claxton, LD and Lewtas, J;Mutagenicity of Derivatives and Metabolites of 1-Nitropyrene: Activation by Rat Liver S9 and Bacterial Enzymes; Mutat. Res. 138(2-3):113-125, 1984
1606-67-3	1-Aminopyrene	Nc1ccc2ccc3cccc4ccc1c2c34	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Ball, LM, Kohan, MJ, Claxton, LD and Lewtas, J;Mutagenicity of Derivatives and Metabolites of 1-Nitropyrene: Activation by Rat Liver S9 and Bacterial Enzymes; Mutat. Res. 138(2-3):113-125, 1984
50-32-8	Benzo[a]pyrene	c1cccc2cc3ccc4cccc5ccc(c12)c3c45	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Chemicals Evaluation and Research Institute, Japan
53-70-3	1,2:5,6-Dibenzanthracene; Dibenz(A,H)Anthracene	c1cccc2ccc3cc4c5ccccc5ccc4cc3c12	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
56-49-5	3-methylcholanthrene	Cc1ccc2cc3c4ccccc4ccc3c3CCc1c23	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
85-01-8	Phenanthrene	c1cccc2ccc3ccccc3c12	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
86-28-2	9-Ethylcarbazole	CCN1c2ccccc2-c2ccccc12	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
129-00-0	Pyrene	c1ccc2ccc3cccc4ccc1c2c34	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
192-97-2	Benzo[e]pyrene	c1cccc2c1c1cccc3ccc4cccc2c4c13	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Chemicals Evaluation and Research Institute, Japan
205-99-2	Benzo(b)fluoranthene	c1cccc2cc3c4ccccc4c4cccc(c12)c34	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
1484-12-4	N-Methylcarbazole	CN1c2ccccc2-c2ccccc12	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	LaVoie, E. J., G. Briggs, V. Bedenko, D. Hoffmann, Mutagenicity of Substituted Carbazoles in Salmonella typhimurium, Mutat. Res. 101 (1982), 141 – 150
18024-11-8	1,4,9-Trimethylcarbazole	Cc1ccc(C)c2c1-c1ccccc1N2C	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
6109-97-3	Carbazole, 3-amino-9-ethyl-, hydrochloride	CCN1c2ccccc2-c2cc(N{+}.Cl{-})ccc12	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
313-67-7	Aristolochic acid	COc1cccc2c1cc(c1c(cc3OCOc3c21)C(O)=O)[N+]([O-])=O	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Chakrabarty, Sn., Pakrashi, A. and Siddiqui, Kai.; Aristolic Acid An Antifertility Agent Is Non-Mutagenic To Bacterial System; Indian J. Pharmacol. 19(1):26-31, 1987
56-55-3	Benz(a)anthracene	c1cccc2ccc3cc4ccccc4cc3c12	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Brown, Jp. and Brown, Rj.; Mutagenesis by 9,10-Anthraquinone Derivatives and Related Compounds in Salmonella Typhimurium; Mutat. Res. 40:203-224, 1976
58917-67-2	Benzo(a)pyrene diolepoxide I	OC1C(O)C2C(c3c1cc1ccc4cccc5ccc3c1c45)O2	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	GREEN,JL, PAN,YHL AND REED,GA; MUTAGENICITY OF BENZO[A]PYRENE BAY-REGION SULFONATES; CARCINOGENESIS 12(7):1359-1362, 1991
1086-00-6	1-Chloromethylpyrene	ClCc1ccc2ccc3cccc4ccc1c2c34	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Ashby, J., Gallagher, Je., Kohan, M., Tinwell, H., Kimber, I., Paton, D., Callander, Rd. and Chouroulinkov, I.; 1-Chloromethylpyrene: A Reference Skin Sensitizer And Genotoxin; Mutat. Res. 243(4):281-9, 1990
218-01-9	chrysene;chrysene benzophenanthrene	c1cccc2ccc3c4ccccc4ccc3c12	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	GLATT,H, SEIDEL,A, BOCHNITSCHEK,W, MARQUARDT,H, MARQUARDT,H, HODGSON,RM, GROVER,PL AND OESCH,F; MUTAGENIC AND CELL-TRANSFORMING ACTIVITIES OF TRIOL-EPOXIDES AS COMPARED TO OTHER CHRYSENE METABOLITES; CANCER RES. 46(9): 4556-4565, 1986
7496-02-8	6-nitrochrysene	[O-][N+](=O)c1cc2c3ccccc3ccc2c2ccccc12	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	EL-BAYOUMY,K, DELCLOS,KB, HEFLICH,RH, WALKER,R, SHIUE,GH AND HECHT,SS; MUTAGENICITY, METABOLISM AND DNA ADDUCT FORMATION OF 6-NITROCHRYSENE IN SALMONELLA TYPHIMURIUM; MUTAGENESIS 4(3):235-240, 1989
5522-43-0	1-nitropyrene;pyrene, 1-nitro-	[O-][N+](=O)c1ccc2ccc3cccc4ccc1c2c34	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	EL-BAYOUMY,K AND HECHT,SS; MUTAGENICITY OF K-REGION DERIVATIVES OF 1-NITROPYRENE; REMARKABLE ACTIVITY OF 1- AND 3-NITRO-5H-PHENANTHRO[4,5-BCD]PYRAN-5-ONE; MUTAT. RES. 170(1-2):31-40, 1986
2409-36-1	9-Hydroxymethylcarbazole	OCN1c2ccccc2-c2ccccc12	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	LaVoie, E. J., G. Briggs, V. Bedenko, D. Hoffmann, Mutagenicity of Substituted Carbazoles in Salmonella typhimurium, Mutat. Res. 101 (1982), 141 – 150.