CAS	Chem.name	Chem.SMILES	#Observed Mutagenicity without S9	#Observed Mutagenicity with S9	Bioassay - 	Reference(s) -
121-14-2	2,4-Dinitrotoluene_(Purified)	Cc1ccc(cc1[N+]([O-])=O)[N+]([O-])=O	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
1817-73-8	2-Bromo-4,6-Dinitroaniline	Nc1c(Br)cc(cc1[N+]([O-])=O)[N+]([O-])=O	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
3468-63-1	Pigment_Orange_5	Oc1ccc2ccccc2c1N=Nc1ccc(cc1[N+]([O-])=O)[N+]([O-])=O	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
618-87-1	Aniline,_3,5-Dinitro-	Nc1cc(cc(c1)[N+]([O-])=O)[N+]([O-])=O	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
99-65-0	Benzene,_M-Dinitro-	[O-][N+](=O)c1cccc(c1)[N+]([O-])=O	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
99-35-4	Benzene,_1,3,5-Trinitro-	[O-][N+](=O)c1cc(cc(c1)[N+]([O-])=O)[N+]([O-])=O	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
70-34-8	1-Fluoro-2,4-Dinitrobenzene	[O-][N+](=O)c1ccc(F)c(c1)[N+]([O-])=O	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
88-88-0	Picryl_Chloride	[O-][N+](=O)c1cc(c(Cl)c(c1)[N+]([O-])=O)[N+]([O-])=O	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
96-91-3	2-Amino-4,6-Dinitrophenol	Nc1cc(cc(c1O)[N+]([O-])=O)[N+]([O-])=O	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
97-02-9	2,4-Dinitroaniline	Nc1ccc(cc1[N+]([O-])=O)[N+]([O-])=O	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
100-25-4	Benzene,_P-Dinitro-	[O-][N+](=O)c1ccc(cc1)[N+]([O-])=O	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
119-26-6	Hydrazine,_(2,4-Dinitrophenyl)-	NNc1ccc(cc1[N+]([O-])=O)[N+]([O-])=O	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	U.S.Environmental Protection Agency Gene-Tox Program. Mutation Research, 168, (1986) pp. 69-240
97-00-7	1-Chloro-2,4-dinitrobenzene	[O-][N+](=O)c1ccc(Cl)c(c1)[N+]([O-])=O	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
584-48-5	1-bromo-2,4-dinitrobenzene	[O-][N+](=O)c1ccc(Br)c(c1)[N+]([O-])=O	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
709-49-9	1-iodo-2,4-dinitrobenzene	[O-][N+](=O)c1ccc(I)c(c1)[N+]([O-])=O	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	GUPTA,RL, SAINI,BHK AND JUNEJA,TR;  MUTAT. RES. 381(1):41-47, 1997
88-89-1	Trinitrophenol, Picric acid	Oc1c(cc(cc1[N+]([O-])=O)[N+]([O-])=O)[N+]([O-])=O	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	NIHS Japan
59283-76-0	2-Hydroxylamino-4,6-dinitrotoluene	Cc1c(NO)cc(cc1[N+]([O-])=O)[N+]([O-])=O	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
606-20-2	2,6-dinitrotoluene	Cc1c(cccc1[N+]([O-])=O)[N+]([O-])=O	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	KAWAI,A, GOTO,S, MATSUMOTO,Y AND MATSUSHITA,H; MUTAGENICITY OF ALIPHATIC AND AROMATIC NITRO COMPOUNDS; SANGYO IGAKU 29(1):34-55, 1987
39300-45-3	dinocap	CC=CC(=O)Oc1c(cc(cc1C(C)(C)CC(C)(C)C)[N+]([O-])=O)[N+]([O-])=O	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	MORIYA,M OHTA,T WATANABE,K MIYAZAWA,T KATO,K AND SHIRASU,Y; FURTHER MUTAGENICITY STUDIES ON PESTICIDES IN BACTERIAL REVERSION ASSAY SYSTEMS; MUTAT. RES. 116(3-4):185-216,1982
1582-09-8	Trifluralin	CCCN(CCC)c1c(cc(cc1[N+]([O-])=O)C(F)(F)F)[N+]([O-])=O	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Diril N., S. Sumer, Mutagenicity of Trifluralin in Salmonella/Microsome Assay Under Various metabolic Activation Conditions, Toxicol. & Environ. Chem. 48(1-2) (1995), 119 - 124 (Abstract)
51868-46-3	c.i. disperse blue 373	COc1cc(N=Nc2c(Br)cc(cc2[N+]([O-])=O)[N+]([O-])=O)c(NC(C)=O)cc1N(CC=C)CC=C	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	de Aragao Umbuzeiro, G., Freeman, H.S., Warren, S.H., de Oliveira, D.P., Terao, Y., Watanabe, T., Claxton, L.D., The contribution of azo dyes to the mutagenic activity of the Cristais River. Chemosphere, 2005, 60(1), 55-64.
56548-64-2	2-[(2-bromo-4,6-dinitrophenyl)azo]-5-(diethylamino)-4-methoxyacetanilde	CCN(CC)c1cc(NC(C)=O)c(cc1OC)N=Nc1c(Br)cc(cc1[N+]([O-])=O)[N+]([O-])=O	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	de Aragao Umbuzeiro, G., Freeman, H., Warren, S.H., Kummrow, F., Claxton, L.D., Mutagenicity evaluation of the commercial product CI Disperse Blue 291 using different protocols of the Salmonella assay. Food Chem. Toxicol., 2005, 43(1), 49-56.
51-28-5	2,4-Dinitro-phenol	Oc1ccc(cc1[N+]([O-])=O)[N+]([O-])=O	in vitro Ames negative	in vitro Ames negative	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
81-14-1	Musk ketone	CC(=O)c1c(C)c(c(c(c1C)[N+]([O-])=O)C(C)(C)C)[N+]([O-])=O	in vitro Ames negative	in vitro Ames negative	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
88-85-7	Dinoseb	CCC(C)c1cc(cc(c1O)[N+]([O-])=O)[N+]([O-])=O	in vitro Ames negative	in vitro Ames negative	Bacterial Reverse Mutation Assay (e.g. Ames Test)	NIHS Japan