CAS	Chem.name	Chem.SMILES	#Observed Mutagenicity without S9	#Observed Mutagenicity with S9	Bioassay - 	Reference(s) -
6-00-3	ICR 174 (13441-95-7);	CCN(CCCNc1ccnc2ccc(OC)cc12)CCCl	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	DeMarini D.M.,et.al, Relationships between structures and mutagenic potencies of 16 heterocyclic nitrogen mustards (ICR compounds) in Salmonella typhimurium Mut.Research, 136 (1984) 185-199
107027-12-3	n-[2-(dimethylamino)ethyl]-2-phenyl-8-quinolinecarboxamide	CN(C)CCNC(=O)c1cccc2ccc(-c3ccccc3)nc12	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Denny, Wa.,  et. al.; Structure- Activity Relationships For The Mutagenic Activity Of Tricyclic Intercalating Agents In Salmonella Typhimurium; Mutat. Res. 232(2):233-241, 1990
56-57-5	4-Nitroquinoline-N-oxide	[O-][N+](=O)c1cc[n+]([O-])c2ccccc12	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	U.S.Environmental Protection Agency Gene-Tox Program. Mutation Research, 168, (1986) pp. 69-240
4637-56-3	4-Hydroxyaminoquinoline-1-oxide	ONc1cc[n+]([O-])c2ccccc12	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25
91-62-3	6-Methylquinoline	Cc1ccc2c(c1)cccn2	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
148-24-3	8-Hydroxyquinoline	Oc1cccc2cccnc12	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
8003-22-3	Solvent Yellow 33	O=C1C(c2ccc3ccccc3n2)C(=O)c2ccccc12	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
91-22-5	Quinoline	c1cccc2cccnc12	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	TAKAHASHI,A AND ONO,H; MUTAGENICITY ASSESSMENT IN 44 EPOXY RESIN HARDENERS IN SALMONELLA TYPHIMURIUM TESTER STRAINS; CHEM. EXPRESS 8(9):785-788, 1993; HASHIMOTO,T, NEGISHI,T, NAMBA,T, HAYAKAWA,S AND HAYATSU,H; MUTAGENICITY OF QUINOLINE DERIVATIVES AND ANALOGS - QUINOXALINE 1,4-DIOXIDE IS A POTENT MUTAGEN; CHEM. PHARM. BULL. 27(8):1954-1956, 1979
86-42-0	Amodiaquine; 4-[(7-Chloroquinolin-4-yl)amino]-2-[(diethylamino)methyl]phenol	CCN(CC)Cc1cc(Nc2ccnc3cc(Cl)ccc23)ccc1O	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Chatterjee, T., A. Muhkopadhyay, K. A. Khan, A. K. Giri, Comparative Mutagenic and Genotoxic Effects of Three Antimalarial Drugs, Chloroquine, Primaquine and Amodiaquine, Mutagen. 13(6) (1998), 619 - 624
54-05-7	Chloroquine	CCN(CC)CCCC(C)Nc1ccnc2cc(Cl)ccc12	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	ESPINOSA-AGUIRRE,JJ, SANTOS,JR AND DE NAVA,CC; INFLUENCE OF THE UVR REPAIR SYSTEM ON THE MUTAGENCIITY OF ANTIPARASITIC DRUGS; MUTAT. RES. 222(3):161-166, 1989
607-35-2	8-nitroquinoline;quinoline, 8-nitro-	[O-][N+](=O)c1cccc2cccnc21	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	U.S. Environmental Protection Agency; Mutation Research, 168 (1986) 69-240
90-34-6	Primaquine;1,4-Pentanediamine,	CC(CCCN)Nc1cc(OC)cc2cccnc12	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	Chatterjee, T., A. Muhkopadhyay, K. A. Khan, A. K. Giri, Comparative Mutagenic and Genotoxic Effects of Three Antimalarial Drugs, Chloroquine, Primaquine and Amodiaquine, Mutagen. 13(6) (1998), 619 – 624