CAS Chem.name Chem.SMILES #Observed Mutagenicity without S9 #Observed Mutagenicity with S9 Bioassay - Reference(s) - 95-70-5 2-Methyl-Benzene-1,4-Diamine Cc1cc(N)ccc1N in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25 100-14-1 P-Nitrobenzyl Chloride [O-][N+](=O)c1ccc(CCl)cc1 in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25 100-22-1 N,N,N',N'-Tetramethyl-P-Phenylenediamine CN(C)c1ccc(cc1)N(C)C in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25 121-88-0 2-Amino-5-Nitrophenol Nc1ccc(cc1O)[N+]([O-])=O in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25 1777-84-0 3-Nitro-P-Acetophenetide CCOc1ccc(NC(C)=O)cc1[N+]([O-])=O in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25 1817-73-8 2-Bromo-4,6-Dinitroaniline Nc1c(Br)cc(cc1[N+]([O-])=O)[N+]([O-])=O in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25 2832-40-8 Disperse Yellow 3 CC(=O)Nc1ccc(cc1)N=Nc1cc(C)ccc1O in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25 5307-14-2 2-Nitro-P-Phenylenediamine Nc1ccc(N)c(c1)[N+]([O-])=O in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25 3468-63-1 Pigment Orange_5 Oc1ccc2ccccc2c1N=Nc1ccc(cc1[N+]([O-])=O)[N+]([O-])=O in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25 618-87-1 Aniline, 3,5-Dinitro- Nc1cc(cc(c1)[N+]([O-])=O)[N+]([O-])=O in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25 99-65-0 Benzene, M-Dinitro- [O-][N+](=O)c1cccc(c1)[N+]([O-])=O in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25 99-35-4 Benzene, 1,3,5-Trinitro- [O-][N+](=O)c1cc(cc(c1)[N+]([O-])=O)[N+]([O-])=O in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25 612-23-7 O-Nitrobenzyl Chloride [O-][N+](=O)c1ccccc1CCl in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25 619-17-0 4-Nitroanthranilic Acid Nc1cc(ccc1C(O)=O)[N+]([O-])=O in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25 619-23-8 M-Nitrobenzyl Chloride [O-][N+](=O)c1cccc(CCl)c1 in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25 70-34-8 1-Fluoro-2,4-Dinitrobenzene [O-][N+](=O)c1ccc(F)c(c1)[N+]([O-])=O in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 95-84-1 2-Amino-4-Methylphenol Cc1ccc(O)c(N)c1 in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25 96-91-3 2-Amino-4,6-Dinitrophenol Nc1cc(cc(c1O)[N+]([O-])=O)[N+]([O-])=O in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25 97-02-9 2,4-Dinitroaniline Nc1ccc(cc1[N+]([O-])=O)[N+]([O-])=O in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25 99-55-8 5-Nitro-O-Toluidine Cc1ccc(cc1N)[N+]([O-])=O in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25 99-56-9 4-Nitro-O-Phenylenediamine Nc1ccc(cc1N)[N+]([O-])=O in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25 99-59-2 5-Nitro-O-Anisidine COc1ccc(cc1N)[N+]([O-])=O in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25 120-66-1 Acetyl-O-Toluidine CC(=O)Nc1ccccc1C in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25 100-01-6 P-Nitroaniline Nc1ccc(cc1)[N+]([O-])=O in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25 100-19-6 P-Nitroacetophenone CC(=O)c1ccc(cc1)[N+]([O-])=O in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25 100-27-6 P-Nitrophenethyl_Alcohol OCCc1ccc(cc1)[N+]([O-])=O in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25 119-34-6 4-Amino-2-Nitrophenol Nc1ccc(O)c(c1)[N+]([O-])=O in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25 3025-77-2 1-((4-Nitrophenyl)Azo)-2-Naphthenamine Nc1ccc2ccccc2c1N=Nc1ccc(cc1)[N+]([O-])=O in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25 100-25-4 Benzene, P-Dinitro- [O-][N+](=O)c1ccc(cc1)[N+]([O-])=O in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25 6358-07-2 2-Amino-4-Chloro-5-Nitrophenol Nc1cc(Cl)c(cc1O)[N+]([O-])=O in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25 99-30-9 2,6-Dichloro-4-Nitroaniline Nc1c(Cl)cc(cc1Cl)[N+]([O-])=O in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25 1635-61-6 5-chloro-2-nitroaniline Nc1cc(Cl)ccc1[N+]([O-])=O in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25 100-16-3 4-Nitrophenylhydrazine NNc1ccc(cc1)[N+]([O-])=O in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25 119-26-6 Hydrazine,_(2,4-dinitrophenyl)- NNc1ccc(cc1[N+]([O-])=O)[N+]([O-])=O in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) U.S.Environmental Protection Agency Gene-Tox Program. Mutation Research, 168, (1986) pp. 69-240 623-10-9 Benzenamine, N-hydroxy-4-methyl- (9CI) Cc1ccc(NO)cc1 in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) NOHMI,T, et al; MUTAT. RES. 136(3):159-168, 1984 3096-64-8 Hydroxylamine, N-(2,5-xylyl)- Cc1ccc(C)c(NO)c1 in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) NOHMI,T. et al ; MUTAT. RES. 136(3):159-168, 1984 10517-47-2 4-Hydroxylaminoacetophenone CC(=O)c1ccc(NO)cc1 in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) PAI,V. et al MUTAT. RES. 151(2):201-207, 1985 16169-16-7 4-Nitrophenylhydroxylamine ONc1ccc(cc1)[N+]([O-])=O in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Corbett, Md. et. al. Carcinogenesis 6(5):727-732, 1985; Pai,V. et. al. Mutat. Res. 151(2):201-207, 1985 43192-07-0 Hydroxylamine, N-(3,4-xylyl)- Cc1ccc(NO)cc1C in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) NOHMI,T. et al ; MUTAT. RES. 136(3):159-168, 1984 67274-52-6 N-Acetyl-4-nitrophenylhydroxylamine CC(=O)N(O)c1ccc(cc1)[N+]([O-])=O in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Corbett, Md. et. al. Carcinogenesis 6(5):727-732, 1985 70853-94-0 2,4-Dimethylphenylhydroxylamine Cc1ccc(NO)c(C)c1 in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) NOHMI,T, et al MUTAT. RES. 136(3):159-168, 1984 115084-47-4 Benzenamine, 4-((4-amino-3-chlorophenyl)methyl)-2-chloro-N-hydroxy- Nc1ccc(Cc2ccc(NO)c(Cl)c2)cc1Cl in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) KUSLIKIS,BI. et al, MUTAGENESIS 6(1):19-24, 1991 97-00-7 1-Chloro-2,4-dinitrobenzene [O-][N+](=O)c1ccc(Cl)c(c1)[N+]([O-])=O in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25 584-48-5 1-bromo-2,4-dinitrobenzene [O-][N+](=O)c1ccc(Br)c(c1)[N+]([O-])=O in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25 709-49-9 1-iodo-2,4-dinitrobenzene [O-][N+](=O)c1ccc(I)c(c1)[N+]([O-])=O in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) GUPTA,RL, SAINI,BHK AND JUNEJA,TR; MUTAT. RES. 381(1):41-47, 1997 55936-76-0 Benzoic_acid,_4-((4-((acetyloxy)methylamino)phenyl)azo)-,_methyl_ester_(9CI) COC(=O)c1ccc(cc1)N=Nc1ccc(cc1)N(C)OC(C)=O in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25 55936-77-1 Benzenamine,_N-(acetyloxy)-N-methyl-4-(phenylazo)-_(9CI) CN(OC(C)=O)c1ccc(cc1)N=Nc1ccccc1 in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) U.S.Environmental Protection Agency Gene-Tox Program. Mutation Research, 168, (1986) pp. 69-240 99-09-2 m-nitroaniline Nc1cccc(c1)[N+]([O-])=O in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) NIHS Japan 88-89-1 Trinitrophenol, Picric acid Oc1c(cc(cc1[N+]([O-])=O)[N+]([O-])=O)[N+]([O-])=O in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) NIHS Japan 95-80-7 Toluene-2,4-diamine Cc1ccc(N)cc1N in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) WATANABE,T. et al; STUDIES ON THE OXIDATION PRODUCTS FROM 2,4-DIAMINOTOLUENE BY HYDROGEN PEROXIDE AND THEIR MUTAGENICITIES. II, MUTAT. RES. 225(1-2):15-19, 1989 108-45-2 1,3-Benzenediamine Nc1cccc(N)c1 in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) GENTILE,JM. Et al; MUTAGENICITY OF SELECTED ANILINE DERIVATIVES TO SALMONELLA FOLLOWING PLANT ACTIVATION AND MAMMALIAN HEPATIC ACTIVATION; MUTAT. RES. 188(3):185-196, 1987 62625-14-3 Phenol, 2-amino-6-chloro-4-nitro-, hydrochloride (1:1) [Cl-].[N+H3]c1cc(cc(Cl)c1O)[N+]([O-])=O in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25 56413-75-3 o-Nitrophenylhydrazine hydrochloride Cl.NNc1ccccc1[N+]([O-])=O in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25 61702-44-1 2-Chloro-p-phenylenediamine sulfate OS(O)(=O)=O.Nc1ccc(N)c(Cl)c1 in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25 185376-54-9 2,4-Dihydroxyamino-6-nitrotoluene Cc1c(NO)cc(NO)cc1[N+]([O-])=O in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) PADDA,RS. et al ENVIRON. TOXICOL. CHEM. 19(12):2871-2875, 2000 5131-58-8 4-Nitro-1,3-benzenediamine Nc1ccc(c(N)c1)[N+]([O-])=O in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 5131-60-2 4-Chloro-m-phenylenediamine Nc1ccc(Cl)c(N)c1 in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 17026-81-2 N-(3-Amino-4-ethoxyphenyl)acetamide CCOc1ccc(NC(C)=O)cc1N in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 39156-41-7 2,4-Diaminoanisole sulfate OS(O)(=O)=O.COc1ccc(N)cc1N in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 7227-92-1 1-(4-Nitrophenyl)-3,3-dimethyltriazene CN(C)N=Nc1ccc(cc1)[N+]([O-])=O in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Cerna, M., Lepsi, P., Rossner, P. and Pohlova, H.; Mutagenicity of Some Substituted 1-Phenyl-3,3-Dimethyltriazenes. I. The Salmonella/Mammalian Microsome Assay and Repair Test; Mutat. Res. 190(3):177-182, 1987 6530-27-4 N-Hydroxy-4-aminoazobenzene ONc1ccc(cc1)N=Nc1ccccc1 in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25 126485-28-7 6-Amino-3-[4-(4-Diethylaminophenylazo)-2-Methoxyphenylazo]-4-Hydroxy-2-Naphthylenesulfonic CCN(CC)c1ccc(cc1)N=NC1=CCC(N=Nc2c(O)c3cc(N)ccc3cc2S(O)(=O)=O)C(OC)=C1 in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 60-09-3 Solvent Yellow 1 Nc1ccc(cc1)N=Nc1ccccc1 in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 87-59-2 2,3-Xylidine Cc1cccc(N)c1C in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 89-63-4 4-Chloro-2-Nitroaniline Nc1ccc(Cl)cc1[N+]([O-])=O in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 91-08-7 Toluene_2,6-diisocyanate Cc1c(cccc1N=C=O)N=C=O in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 93-05-0 N,N-Diethyl-P-Phenylenediamine CCN(CC)c1ccc(N)cc1 in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 95-64-7 3,4-Xylidine Cc1ccc(N)cc1C in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 95-68-1 2,4-Dimethylaniline Cc1ccc(N)c(C)c1 in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 95-78-3 2,5-xylidine Cc1ccc(C)c(N)c1 in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 95-83-0 4-chloro-o-phenylenediamine Nc1ccc(Cl)cc1N in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 99-57-0 2-Amino-4-Nitrophenol Nc1cc(ccc1O)[N+]([O-])=O in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 99-98-9 N,N-Dimethyl-p-Phenylenediamine CN(C)c1ccc(N)cc1 in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 101-14-4 4,4'-Methylenebis(2-Chloroaniline) Nc1ccc(Cc2ccc(N)c(Cl)c2)cc1Cl in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 102-28-3 m-Aminoacetanilide CC(=O)Nc1cccc(N)c1 in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 102-50-1 m-Cresidine COc1ccc(N)c(C)c1 in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 103-89-9 N-Acetyl-p-Toluidine CC(=O)Nc1ccc(C)cc1 in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 108-69-0 3,5-Xylidine Cc1cc(C)cc(N)c1 in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 120-37-6 Phenol, 3-(ethylamino)-4-methyl-; 3-Ethylamino-4-Methylphenol CCNc1cc(O)ccc1C in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) ZEIGER,E, ANDERSON,B, HAWORTH,S, LAWLOR,T AND MORTELMANS,K; SALMONELLA MUTAGENICITY TESTS: IV. RESULTS FROM THE TESTING OF 300 CHEMICALS; ENVIRON. MOL. MUTAGEN. 11(SUPPL.12):1-158, 1988 120-71-8 p-Cresidine COc1ccc(C)cc1N in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 122-80-5 p-Aminoacetanilide CC(=O)Nc1ccc(N)cc1 in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 137-09-7 2,4-Diaminophenol Nc1ccc(O)c(N)c1 in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 138-89-6 N,N-Dimethyl-p-Nitrosoaniline CN(C)c1ccc(cc1)N=O in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 493-52-7 C.I. Acid Red 2 CN(C)c1ccc(cc1)N=Nc1ccccc1C(O)=O in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 496-72-0 3,4-Diaminotoluene Cc1ccc(N)c(N)c1 in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 532-82-1 C.I. Basic Orange 2 Nc1ccc(N=Nc2ccccc2)c(N)c1 in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 584-84-9 2,4-Toluene Diisocyanate Cc1ccc(cc1N=C=O)N=C=O in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 609-20-1 2,6-Dichloro-benzene-1,4-diamine Nc1cc(Cl)c(N)c(Cl)c1 in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 2835-95-2 3-Amino-6-Methylphenol Cc1ccc(N)cc1O in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 3761-53-3 C.I. Acid Red 26 Cc1ccc(N=Nc2c(O)c(cc3cc(ccc23)S(O)(=O)=O)S(O)(=O)=O)c(C)c1 in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 6219-89-2 4-Amino-4'-Hydroxy-3-Methyldiphenylamine Cc1cc(Nc2ccc(O)cc2)ccc1N in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 13684-63-4 Phenmedipham COC(=O)Nc1cccc(OC(=O)Nc2cccc(C)c2)c1 in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 15121-84-3 O-Nitrophenethyl alcohol OCCc1ccccc1[N+]([O-])=O in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 16452-01-0 O-Cresidine COc1cc(N)ccc1C in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 126335-31-7 Benzenamine,_4-((4-Amino-3-Methoxyphenyl)Azo)-N,N-Diethyl- CCN(CC)c1ccc(cc1)N=Nc1ccc(N)c(OC)c1 in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 126335-36-2 Ethanol, 2,2'-((4-((4-Amino-3-Methoxyphenyl)Azo)Phenyl)Imino)Bis- COc1cc(ccc1N)N=Nc1ccc(cc1)N(CCO)CCO in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 87-62-7 2,6-Xylidine Cc1cccc(C)c1N in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) NIHS Japan 99-88-7 Cumidine; 4-isopropylaniline; p-Isopropylaniline CC(C)c1ccc(N)cc1 in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) NIHS Japan 540-23-8 p-Toluidine hydrochloride Cl.Cc1ccc(N)cc1 in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 4801-39-2 Glycinanilide, hydrochloride [Cl-].CC(=O)Nc1ccccc1[N+H3] in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 15481-70-6 Toluene-2,6-diamine, dihydrochloride Cl.Cl.Cc1c(N)cccc1N in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 127750-13-4 2-Naphthalenesulfonic acid, 6-amino-4-hydroxy-3-((2-methoxy-4-(phenylazo)phenyl)azo)-, monosodium salt [Na+].COc1cc(ccc1N=Nc1c(O)c2cc(N)ccc2cc1S([O-])(=O)=O)N=Nc1ccccc1 in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 34256-82-1 Acetochlor CCOCN(C(=O)CCl)c1c(C)cccc1CC in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) CLH report ; Proposal for Harmonized Classification and Labelling , Based on Regulation (EC) No 1272/2008 (CLP Regulation), Annex VI, Part 2, Substance Name: Acetochlor, September 2013 2835-98-5 6-amino-m-cresol Cc1ccc(N)c(O)c1 in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) SHORT-TERM TEST PROGRAM SPONSORED BY THE DIVISION OF CANCER BIOLOGY, NATIONAL CANCER INSTITUTE, MS. ELLEN ZAIKA, ASSISTANT PROJECT OFFICER , p. Y98 823-40-5 2,6-diaminotoluene Cc1c(N)cccc1N in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) SAYAMA,M, MORI,M, SHIROKAWA,T, INOUE,M, MIYAHARA,T AND KOZUKA,H; MUTAGENICITY OF 2,6-DINITROTOLUENE AND ITS METABOLITES, AND THEIR RELATED COMPOUNDS IN SALMONELLA TYPHIMURIUM; MUTAT. RES. 226(3):181-184, 1989 60-11-7 4-(dimethylamino)azobenzene CN(C)c1ccc(cc1)N=Nc1ccccc1 in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) ZEIGER,E, ANDERSON,B, HAWORTH,S, LAWLOR,T, MORTELMANS,K AND SPECK,W; SALMONELLA MUTAGENICITY TESTS: III. RESULTS FROM THE TESTING OF 255 CHEMICALS; ENVIRON. MOL. MUTAGEN. 9(SUPPL.9):1-110, 1987 607-59-0 Aniline, N,N-dimethyl-p-(1-naphthylazo)- CN(C)c1ccc(cc1)N=Nc1cccc2ccccc12 in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) SHORT-TERM TEST PROGRAM SPONSORED BY THE DIVISION OF CANCER BIOLOGY, NATIONAL CANCER INSTITUTE, MS. ELLEN ZAIKA, ASSISTANT PROJECT OFFICER , p. Y82 88-74-4 2-Nitroaniline Nc1ccccc1[N+]([O-])=O in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) D. Kirkland, L. Reeve, D. Gatehouse, P. Vanparys, A core in vitro genotoxicity battery comprising the Ames test plus the in vitro micronucleus test is sufficient to detect rodent carcinogens and in vivo genotoxins, Mutat. Res. 721 (2011) 27-73. 95-53-4 2-methylaniline Cc1ccccc1N in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Hamzah,Ry and El-Torkey,Nm; MUTAGENIC ACTIVITIES OF AROMATIC AMINES IN SALMONELLA TYPHIMURIUM AND ITS EFFECT ON RAT DRUG METABOLIZING ENZYMES; ARAB GULF J. SCI. RES. 13(1):13-23, 1995 88-05-1 2,4,6-trimethylaniline Cc1cc(C)c(N)c(C)c1 in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) SHIMIZU,H AND TAKEMURA,N; MUTAGENICITY OF SOME ANILINE DERIVATIVES; OCCUP. HEALTH CHEM. IND., PROC. INT. CONGR., 11TH:497-506, 1983 5042-54-6 2,4-diamino-5-methylazobenzene Cc1cc(N=Nc2ccccc2)c(N)cc1N in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Sandhu, P., Chipman, J.K., Bacterial mutagenesis and hepatocyte unscheduled DNA synthesis induced by chrysoidine azo-dye components. Mutat. Res., 1990, 240(3), 227-236. 13301-61-6 c.i. disperse orange 37 CCN(CCC#N)c1ccc(cc1)N=Nc1c(Cl)cc(cc1Cl)[N+]([O-])=O in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) de Aragao Umbuzeiro, G., Freeman, H.S., Warren, S.H., de Oliveira, D.P., Terao, Y., Watanabe, T., Claxton, L.D., The contribution of azo dyes to the mutagenic activity of the Cristais River. Chemosphere, 2005, 60(1), 55-64. 14097-03-1 c.i. basic red 18 CCN(CC[N+](C)(C)C)c1ccc(cc1)N=Nc1ccc(cc1Cl)[N+]([O-])=O in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Helmes, C.T., Sigman, C.C., Fung, V.A., Thompson, K., Doeltz, M.K., Mackie, M., Klein, T.E., Lent, D., A study of azo and nitro dyes for the selection of candidates for carcinogen bioassay. J. Environ. Sci. Health A Environ. Sci. Eng., 1984, 19(2), 97-231. 51868-46-3 c.i. disperse blue 373 COc1cc(N=Nc2c(Br)cc(cc2[N+]([O-])=O)[N+]([O-])=O)c(NC(C)=O)cc1N(CC=C)CC=C in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) de Aragao Umbuzeiro, G., Freeman, H.S., Warren, S.H., de Oliveira, D.P., Terao, Y., Watanabe, T., Claxton, L.D., The contribution of azo dyes to the mutagenic activity of the Cristais River. Chemosphere, 2005, 60(1), 55-64. 56548-64-2 2-[(2-bromo-4,6-dinitrophenyl)azo]-5-(diethylamino)-4-methoxyacetanilde CCN(CC)c1cc(NC(C)=O)c(cc1OC)N=Nc1c(Br)cc(cc1[N+]([O-])=O)[N+]([O-])=O in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) de Aragao Umbuzeiro, G., Freeman, H., Warren, S.H., Kummrow, F., Claxton, L.D., Mutagenicity evaluation of the commercial product CI Disperse Blue 291 using different protocols of the Salmonella assay. Food Chem. Toxicol., 2005, 43(1), 49-56. 84434-42-4 2,4-diamino-3-methylazobenzene Cc1c(N)ccc(N=Nc2ccccc2)c1N in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Sandhu, P., Chipman, J.K., Bacterial mutagenesis and hepatocyte unscheduled DNA synthesis induced by chrysoidine azo-dye components. Mutat. Res., 1990, 240(3), 227-236. 104226-21-3 4'-amino-6-methyl-4-n,n-di(beta-hydroxyethylamino)azobenzene Cc1cc(ccc1N=Nc1ccc(N)cc1)N(CCO)CCO in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) SCCS (Scientific Committee on Consumer Safety), Opinion on HC Yellow n? 7, 21 September 2010. 547-58-0 methyl orange [Na+].CN(C)c1ccc(cc1)N=Nc1ccc(cc1)S([O-])(=O)=O in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Ben Mansour, H., Barillier, D., Corroler, D., Ghedira, K., Chekir-Ghedira, L., Mosrati, R., In vitro study of DNA damage induced by acid orange 52 and its biodegradation derivatives. Environ. Toxicol. Chem., 2009, 28(3), 489-495. 2872-52-8 disperse red 1 CCN(CCO)c1ccc(cc1)N=Nc1ccc(cc1)[N+]([O-])=O in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Ferraz, E.R., Umbuzeiro, G.A., de-Almeida, G., Caloto-Oliveira, A., Chequer, F.M., Zanoni, M.V., Dorta, D.J., Oliveira, D.P., Differential toxicity of Disperse Red 1 and Disperse Red 13 in the Ames test, HepG2 cytotoxicity assay, and Daphnia acute toxicity test. Environ. Toxicol., 2011, 26(5), 489-497. 3179-89-3 c.i. disperse red 17 Cc1cc(ccc1N=Nc1ccc(cc1)[N+]([O-])=O)N(CCO)CCO in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) SCCS (Scientific Committee on Consumer Safety), Opinion on Disperse Red 17, 12 December 2013. 20721-50-0 2, 2'[[4-[(4-aminophenyl)azo]phenyl]imino]bisethanol Nc1ccc(cc1)N=Nc1ccc(cc1)N(CCO)CCO in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) SCCS (Scientific Committee on Consumer Safety), Opinion on Disperse Black 9, 23 March 2010. 6428-31-5 2,7-naphthalenedisulfonic acid, 4-amino-3,6-bis[[4-[(2,4-diaminophenyl)azo]phenyl]azo]-5-hydroxy-, disodium salt [Na+].[Na+].Nc1ccc(N=Nc2ccc(cc2)N=Nc2c(N)c3c(O)c(N=Nc4ccc(cc4)N=Nc4ccc(N)cc4N)c(cc3cc2S([O-])(=O)=O)S([O-])(=O)=O)c(N)c1 in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Disodium 4-amino-3,6-bis[[4-[(2,4-diaminophenyl)azo]phenyl]azo]-5-hydroxynaphthalene-2,7-disulphonate, CAS No 6428-31-5. ECHA Legal notice, Registration dossier. http://echa.europa.eu/registration-dossier/-/registered-dossier/11334 3118-97-6 c.i. solvent orange 7 Cc1ccc(N=Nc2c(O)ccc3ccccc23)c(C)c1 in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food on a request from the Commission to Review the toxicology of a number of dyes illegally present in food in the EU Question number EFSA-2005-082. EFSA J., 2005, 263, 1-71. 23355-64-8 c.i. disperse brown 1 OCCN(CCO)c1ccc(N=Nc2c(Cl)cc(cc2Cl)[N+]([O-])=O)c(Cl)c1 in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Seifried, H.E., Seifried, R.M., Clarke, J.J., Junghans, T.B., San, R.H., A compilation of two decades of mutagenicity test results with the Ames Salmonella typhimurium and L5178Y mouse lymphoma cell mutation assays. Chem. Res. Toxicol., 2006, 19(5), 627-644. 3441-14-3 2-naphthalenesulfonic acid, 3-[[4-(acetylamino)phenyl]azo]-4-hydroxy-7-[[[[5-hydroxy-6-(phenylazo)-7-sulfo-2-naphthalenyl]amino]carbonyl]amino]-, disodium salt [Na+].[Na+].CC(=O)Nc1ccc(cc1)N=Nc1c(O)c2ccc(NC(=O)Nc3ccc4c(O)c(N=Nc5ccccc5)c(cc4c3)S([O-])(=O)=O)cc2cc1S([O-])(=O)=O in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) C.I. Direct Red 23, CAS No 3441-14-3. TOXNET, CCRIS, 2011. 126513-99-3 2-Naphthalenesulfonic acid, 6-amino-3-((4-((4-(bis(2-hydroxyethyl)amino)phenyl)azo)-2-methoxyphenyl)azo)-4-hydroxy- COc1cc(ccc1N=Nc1c(O)c2cc(N)ccc2cc1S(O)(=O)=O)N=Nc1ccc(cc1)N(CCO)CCO in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 97404-02-9 2-[(4-aminophenyl)azo]-1,3-dimethyl-1h-imidazolium chloride [Cl-].Cn1cc[n+](C)c1N=Nc1ccc(N)cc1 in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) SCCS (Scientific Committee on Consumer Safety), Opinion on Basic Orange 31, 14 December 2010. 140-56-7 Methyl Orange B CN(C)c1ccc(cc1)N=NS(O)(=O)=O in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25 1937-37-7 C.I. Direct Black 38 [Na+].[Na+].Nc1ccc(N=Nc2ccc(cc2)-c2ccc(cc2)N=Nc2c(N)c3c(O)c(N=Nc4ccccc4)c(cc3cc2S([O-])(=O)=O)S([O-])(=O)=O)c(N)c1 in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 16071-86-6 c.i. direct brown 95 [Na+].[Na+].[Cu+2].Oc1ccc(cc1C([O-])=O)N=Nc1ccc(cc1)-c1ccc(cc1)N=Nc1c(O)ccc(N=Nc2cc(ccc2[O-])S([O-])(=O)=O)c1[O-] in vitro Ames negative in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) Zhou,Y, You,X and Ye,X; MUTAGENICITY OF BENZIDINES AND THEIR CONGENER DERIVATIVE DYES; HUANJING KEXUE 8(2):31-34, 1987 39300-45-3 Dinocap CC=CC(=O)Oc1c(cc(cc1C(C)(C)CC(C)(C)C)[N+]([O-])=O)[N+]([O-])=O in vitro Ames positive in vitro Ames positive Bacterial Reverse Mutation Assay (e.g. Ames Test) MORIYA,M OHTA,T WATANABE,K MIYAZAWA,T KATO,K AND SHIRASU,Y; FURTHER MUTAGENICITY STUDIES ON PESTICIDES IN BACTERIAL REVERSION ASSAY SYSTEMS; MUTAT. RES. 116(3-4):185-216,1982 51-28-5 2,4-Dinitro-phenol Oc1ccc(cc1[N+]([O-])=O)[N+]([O-])=O in vitro Ames negative in vitro Ames negative Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 98-16-8 m-(Trifluoromethyl)aniline Nc1cccc(c1)C(F)(F)F in vitro Ames negative in vitro Ames negative Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 99-08-1 3-Nitrotoluene Cc1cccc(c1)[N+]([O-])=O in vitro Ames negative in vitro Ames negative Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 101-72-4 N-Isopropyl-N'-phenyl-para-phenylenediamine CC(C)Nc1ccc(Nc2ccccc2)cc1 in vitro Ames negative in vitro Ames negative Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 108-44-1 3-Aminotoluene Cc1cccc(N)c1 in vitro Ames negative in vitro Ames negative Bacterial Reverse Mutation Assay (e.g. Ames Test) NIHS Japan 2164-17-2 Fluometuron CN(C)C(=O)Nc1cccc(c1)C(F)(F)F in vitro Ames negative in vitro Ames negative Bacterial Reverse Mutation Assay (e.g. Ames Test) National Toxicology program. P&G Inventory 88-53-9 Benzenesulfonic Acid, 2-Amino-5-Chloro-4-Methyl- Cc1cc(N)c(cc1Cl)S(O)(=O)=O in vitro Ames negative in vitro Ames negative Bacterial Reverse Mutation Assay (e.g. Ames Test) NIHS Japan 88-44-8 4-Amino-M-Toluenesulfonic Acid;_Benzenesulfonic_Acid,_2-Amino-5-Methyl- Cc1ccc(N)c(c1)S(O)(=O)=O in vitro Ames negative in vitro Ames negative Bacterial Reverse Mutation Assay (e.g. Ames Test) NIHS Japan 93-68-5 2'-Methylacetoacetanilide CC(=O)CC(=O)Nc1ccccc1C in vitro Ames negative in vitro Ames negative Bacterial Reverse Mutation Assay (e.g. Ames Test) NIHS Japan 5281-04-9 D & C Red No 7 [Ca+2].Cc1ccc(N=Nc2c(O)c(cc3ccccc23)C([O-])=O)c(c1)S([O-])(=O)=O in vitro Ames negative in vitro Ames negative Bacterial Reverse Mutation Assay (e.g. Ames Test) NIHS Japan 88-85-7 Dinoseb CCC(C)c1cc(cc(c1O)[N+]([O-])=O)[N+]([O-])=O in vitro Ames negative in vitro Ames negative Bacterial Reverse Mutation Assay (e.g. Ames Test) NIHS Japan 5858-81-1 c.i. pigment red 57, disodium salt [Na+].[Na+].Cc1ccc(N=Nc2c(O)c(cc3ccccc23)C([O-])=O)c(c1)S([O-])(=O)=O in vitro Ames negative in vitro Ames negative Bacterial Reverse Mutation Assay (e.g. Ames Test) SCCNFP (Scientific Committee on Cosmetic Products and Non-Food Products Intended for Consumers), Evaluation and opinion on Pigment Red 57, 25 May 2004. 7023-61-2 2-naphthalenecarboxylic acid, 4-[(5-chloro-4-methyl-2-sulfophenyl)azo]-3-hydroxy-, calcium salt (1:1) [Ca+2].Cc1cc(c(cc1Cl)N=Nc1c(O)c(cc2ccccc12)C([O-])=O)S([O-])(=O)=O in vitro Ames negative in vitro Ames negative Bacterial Reverse Mutation Assay (e.g. Ames Test) Calcium 4-[(5-chloro-4-methyl-2-sulphonatophenyl)azo]-3-hydroxy-2-naphthoate, CAS No 7023-61-2. ECHA Legal notice, Registration dossier. http://echa.europa.eu/registration-dossier/-/registered-dossier/15275 7585-41-3 2-naphthalenecarboxylic acid, 4-[(5-chloro-4-methyl-2-sulfophenyl)azo]-3-hydroxy-, barium salt (1:1) [Ba+2].Cc1cc(c(cc1Cl)N=Nc1c(O)c(cc2ccccc12)C([O-])=O)S([O-])(=O)=O in vitro Ames negative in vitro Ames negative Bacterial Reverse Mutation Assay (e.g. Ames Test) Barium 4-[(5-chloro-4-methyl-2-sulphonatophenyl)azo]-3-hydroxy-2-naphthoate, CAS No 7585-41-3. ECHA Legal notice, Registration dossier. http://echa.europa.eu/registration-dossier/-/registered-dossier/14735