CAS	Chem.name	Chem.SMILES	#Observed Mutagenicity without S9	#Observed Mutagenicity with S9	Bioassay - 	Reference(s) -
62-44-2	Phenacetin	CCOc1ccc(NC(C)=O)cc1	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	"S. De Flora, P. Russo, M. Pala, G. Fassina, A. Zunino, C. Bennicelli, P. Zanacchi, A. Camoirano, S. Parodi, Assay of phenacetin genotoxicity using in vitro and in vivo test systems, J. Toxicol. Environ. Health. 16 (3-4) (1985) 355-377. J.W. Oldham, R.F. Preston, J.D. Paulson, Mutagenicity testing of selected analgesics in Ames Salmonella strains, J. Appl. Toxicol. 6 (4) (1986) 237-243."
95-70-5	"2-Methyl-Benzene-1,4-Diamine"	Cc1cc(N)ccc1N	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	"Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25"
320-67-2	5-Azacytidine	N=C1NC(=O)N(C2C(O)C(O)C(CO)O2)C=N1	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	"Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25"
105-11-3	P-Benzoquinone Dioxime	ON=C1C=CC(=NO)C=C1	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	"Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25"
94-52-0	6-Nitrobenzimidazole	[O-][N+](=O)c1ccc2[nH]cnc2c1	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	"Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25"
129117-54-0	"1,4-Dimethyl-6-Methoxy-3-Aminocarbazole"	Cc1cc(N)c(C)c2c1Nc1ccc(OC)cc-21	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
7/2/6358	2-Amino-4-Chloro-5-Nitrophenol	Nc1cc(Cl)c(cc1O)[N+]([O-])=O	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	"Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25"
61702-44-1	2-Chloro-p-phenylenediamine sulfate	Nc1ccc(N)cc1Cl_OS(O)(=O)=O	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	"Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25"
581-64-6	Thionine	NC1=CC2C(C=C1)=Nc1ccc(N)cc1S{+}=2.Cl{-}	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	"Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25"
6112-76-1	Mercaptopurine	O_S=C1C2=C(N=CN1)N=CN2	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	"Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25"
39156-41-7	"2,4-Diaminoanisole sulfate"	COc1ccc(N)cc1N_OS(O)(=O)=O	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
86-54-4	Hydralazine	N/N=C1C{P+}2C=CC=CC2=CN=N/1	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	"Kazius J, McGuire R., Bursi R. Journal of Medicinal Chemistry 48 (1), pp. 312-32, 25"
220042-15-9	"2-(4-Nitrophenylamino)-5-(3-benzoylamino-2,4,5-thiadiazolyl)-1,4-benzoquinone"	OC1=CC(=Nc2ccc(cc2)[N+]([O-])=O)C(=O)C=C1c1nnc(NC(=O)c2ccccc2)s1	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	"HASSAN,MA. et al ARCH. PHARM. 331(12):385-388, 1998"
55-55-0	N-methyl-p-aminophenol sulfate	CNc1ccc(O)cc1	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
74-31-7	"N,N'-Diphenyl-P-Phenylenediamine"	c1ccccc1Nc1ccc(Nc2ccccc2)cc1	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
102-50-1	m-Cresidine	Cc1cc(OC)ccc1N	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
137-09-7	"2,4-Diaminophenol"	Nc1ccc(O)c(N)c1	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
156-10-5	p-Nitrosodiphenylamine	O=Nc1ccc(Nc2ccccc2)cc1	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
609-20-1	"2,6-Dichloro-benzene-1,4-diamine"	Nc1cc(Cl)c(N)c(Cl)c1	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
4/8/2735	"Aniline, 2,4-Dimethoxy-"	COc1ccc(N)c(OC)c1	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
6219-89-2	4-Amino-4'-Hydroxy-3-Methyldiphenylamine	Cc1cc(Nc2ccc(O)cc2)ccc1N	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
93-46-9	"Diafen NN; 1,4-Bis(2-naphthylamino)benzene"	c1cccc2ccc(Nc3ccc(Nc4ccc5ccccc5c4)cc3)cc12	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	P&G
86-42-0	Amodiaquine; 4-[(7-Chloroquinolin-4-yl)amino]-2-[(diethylamino)methyl]phenol	CCN(CC)Cc1cc(Nc2ccnc3cc(Cl)ccc23)ccc1O	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	"Chatterjee, T., A. Muhkopadhyay, K. A. Khan, A. K. Giri, Comparative Mutagenic and Genotoxic Effects of Three Antimalarial Drugs, Chloroquine, Primaquine and Amodiaquine, Mutagen. 13(6) (1998), 619 - 624"
50-44-2	6-mercaptopurine;mercaptopurine	S=C1C2=C(NC=N1)N=CN2	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	"MARHAN,J; MUTAGENICITY OF CYTOSTATIC DRUGS IN A BACTERIAL SYSTEM. I. AMES TEST; FOLIA MICROBIOL. 40(5):457-461, 1995"
61-73-4	Methylene Blue	CN(C)C1=CC2C(C=C1)=Nc1ccc(N(C)C)cc1S{+}=2.Cl{-}	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	"SHORT-TERM TEST PROGRAM SPONSORED BY THE DIVISION OF CANCER BIOLOGY, NATIONAL CANCER INSTITUTE, MS. ELLEN ZAIKA, ASSISTANT PROJECT OFFICER , p. Y88"
2429-74-5	C.I. Direct Blue 15	COc1cc(-c2ccc(NN=C3C(S(=O)(=O)O{-}.[Na]{+})=Cc4cc(S(=O)(=O)O{-}.[Na]{+})cc(N)c4C3=O)c(OC)c2)ccc1NN=C1C(S(=O)(=O)O{-}.[Na]{+})=Cc2cc(S(=O)(=O)O{-}.[Na]{+})cc(N)c2C1=O	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	"NCI/NTP CARCINOGENESIS TECHNICAL REPORT SERIES; NATIONAL CANCER INSTITUTE/NATIONAL TOXICOLOGY PROGRAM; U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES, TR-397 Y92"
16071-86-6	c.i. direct brown 95	O=C1C=CC(=NNc2cc3ccc2O{-}.[Cu]{2+}.O{-}S3(=O)=O)C(=O)C1=NNc1ccc(-c2ccc(N=Nc3ccc(O{-}.[Na]{+})c(C(=O)O{-}.[Na]{+})c3)cc2)cc1	in vitro Ames negative	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	"Zhou,Y, You,X and Ye,X; MUTAGENICITY OF BENZIDINES AND THEIR CONGENER DERIVATIVE DYES; HUANJING KEXUE 8(2):31-34, 1987"
569-61-9	C.I. Basic Red 9	Nc1ccc(C(=C2C=CC(=N)C=C2)c2ccc(N)cc2)cc1	in vitro Ames positive	in vitro Ames positive	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
101-72-4	N-Isopropyl-N'-phenyl-para-phenylenediamine	CC(C)Nc1ccc(Nc2ccccc2)cc1	in vitro Ames negative	in vitro Ames negative	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
103-90-2	Acetaminophen	CC(=O)Nc1ccc(O)cc1	in vitro Ames negative	in vitro Ames negative	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
122-39-4	"N,N-Diphenylamine"	c1ccccc1Nc1ccccc1	in vitro Ames negative	in vitro Ames negative	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory
793-24-8	"N-(1,3-Dimethylbutyl)-N'-Phenyl-P-Phenylenediamine"	CC(C)CC(C)Nc1ccc(Nc2ccccc2)cc1	in vitro Ames negative	in vitro Ames negative	Bacterial Reverse Mutation Assay (e.g. Ames Test)	National Toxicology program. P&G Inventory