CAS Chem.name Chem.SMILES #CA_without_S9 #Obs_CA_with_S9 Bioassay - Reference(s) - 72-43-5 Methoxychlor COc1ccc(C(c2ccc(OC)cc2)C(Cl)(Cl)Cl)cc1 negative negative in Vitro Mammalian Chromosome Aberration Test Sofuni, T., Ed. (1998). Data Book of Chromosomal Aberration Test in vitro, Revised Edition. Life-Science Information Center, Tokyo, Japan 75-34-3 1,1-Dichloroethane CC(Cl)Cl negative negative in Vitro Mammalian Chromosome Aberration Test Sofuni, T., Ed. (1998). Data Book of Chromosomal Aberration Test in vitro, Revised Edition. Life-Science Information Center, Tokyo, Japan 79-27-6 1,1,2,2-Tetrabromoethane BrC(Br)C(Br)Br negative negative in Vitro Mammalian Chromosome Aberration Test NIHS Japan 115-32-2 Trichloroethanol, 1,1-Bis(Parachlorophenyl)2,2,2- OC(c1ccc(Cl)cc1)(c1ccc(Cl)cc1)C(Cl)(Cl)Cl negative negative in Vitro Mammalian Chromosome Aberration Test Sofuni, T., Ed. (1998). Data Book of Chromosomal Aberration Test in vitro, Revised Edition. Life-Science Information Center, Tokyo, Japan 127-18-4 Tetrachloroethylene ClC(Cl)=C(Cl)Cl negative negative in Vitro Mammalian Chromosome Aberration Test Sofuni, T., Ed. (1998). Data Book of Chromosomal Aberration Test in vitro, Revised Edition. Life-Science Information Center, Tokyo, Japan 75-35-4 Vinylidene Chloride C=C(Cl)Cl negative positive in Vitro Mammalian Chromosome Aberration Test Sofuni, T., Ed. (1998). Data Book of Chromosomal Aberration Test in vitro, Revised Edition. Life-Science Information Center, Tokyo, Japan 611-19-8 benzene, 1-chloro-2-(chloromethyl)- ClCc1ccccc1Cl negative positive in Vitro Mammalian Chromosome Aberration Test NIHS Japan 79-01-6 Trichloroethylene ClC=C(Cl)Cl negative negative in Vitro Mammalian Chromosome Aberration Test Danish EPA Inventory, Sofuni, T., Ed. (1998). Data Book of Chromosomal Aberration Test In Vitro, Revised Edition. Life-Science Information Center; Tokyo, Japan. 52-68-6 Trichlorfon COP(=O)(C(O)C(Cl)(Cl)Cl)OC positive positive in Vitro Mammalian Chromosome Aberration Test Chemicals Evaluation and Research Institute, Japan 62-73-7 Dichlorvos COP(=O)(OC)OC=C(Cl)Cl positive positive in Vitro Mammalian Chromosome Aberration Test Sofuni, T., Ed. (1998). Data Book of Chromosomal Aberration Test in vitro, Revised Edition. Life-Science Information Center, Tokyo, Japan 133-67-5 Trichloromethiazide NS(=O)(=O)c1cc2c(cc1Cl)NC(C(Cl)Cl)NS2(=O)=O positive positive in Vitro Mammalian Chromosome Aberration Test Sofuni, T., Ed. (1998). Data Book of Chromosomal Aberration Test in vitro, Revised Edition. Life-Science Information Center, Tokyo, Japan 71-55-6 1,1,1-trichloroethane; Ethane, 1,1,1-trichloro-; Chlorten CC(Cl)(Cl)Cl positive positive in Vitro Mammalian Chromosome Aberration Test GALLOWAY,SM, ARMSTRONG, MJ, REUBEN,C, COLMAN,S BROWN,B, CANNON,C, BLOOM,A.D, NAKAMURA,F, AHMED,M. DUK,S, RIMPO,J, MARGOLIN,BH, RESNICK,MA, ANDERSON,B AND ZEIGER,E; CHROMOSOME ABERRATIONS AND SISTER CHROMATID EXCHANGES IN CHINESE HAMSTER OVARY CELLS: EVALUATIONS OF 108 CHEMICALS; ENVIRON. MOL. MUTAGEN. 10(SUPPL. 10):1-175, 1987 2425-06-1 Captafol O=C1C2CC=CCC2C(=O)N1SC(Cl)(Cl)C(Cl)Cl positive positive in Vitro Mammalian Chromosome Aberration Test H. Tezuka, N. Ando, R. Suzuki, M. Terahata, M. Moriya, Y. Shirasu, Sister-chromatid exchanges and chromosomal aberrations in cultured Chinese hamster cells treated with pesticides positive in microbial reversion assays. Mutat. Res., 1980, 78(2),177-191. 100-44-7 Benzyl chloride ClCc1ccccc1 positive positive in Vitro Mammalian Chromosome Aberration Test JAPAN CHEMICAL INDUSTRY ECOLOGY- TOXICOLOGY AND INFORMATION CENTER, JAPAN; MUTAGENICITY TEST DATA OF EXISTING CHEMICAL SUBSTANCES BASED ON THE TOXICITY INVESTIGATION OF THE INDUSTRIAL SAFETY AND HEALTH LAW; (SUPPL), 1997 5216-25-1 alpha,alpha,alpha-Trichloro-4-chlorotoluene Clc1ccc(C(Cl)(Cl)Cl)cc1 positive positive in Vitro Mammalian Chromosome Aberration Test JAPAN CHEMICAL INDUSTRY ECOLOGY- TOXICOLOGY AND INFORMATION CENTER, JAPAN; MUTAGENICITY TEST DATA OF EXISTING CHEMICAL SUBSTANCES BASED ON THE TOXICITY INVESTIGATION OF THE INDUSTRIAL SAFETY AND HEALTH LAW; 1996 79-43-6 dichloracetic acid OC(=O)C(Cl)Cl positive positive in Vitro Mammalian Chromosome Aberration Test JAPAN CHEMICAL INDUSTRY ECOLOGY- TOXICOLOGY AND INFORMATION CENTER, JAPAN; MUTAGENICITY TEST DATA OF EXISTING CHEMICAL SUBSTANCES BASED ON THE TOXICITY INVESTIGATION OF THE INDUSTRIAL SAFETY AND HEALTH LAW; 1996 79-44-7 dimethylcarbamoyl chloride CN(C)C(=O)Cl positive positive in Vitro Mammalian Chromosome Aberration Test Natarajan, A.T. & van Kesteren-van Leeuwen, A.C. (1981) Mutagenic activity of 20 coded com- pounds in chromosone aberrations/sister chromatid exchanges assay using Chinese hamster ovary (CHO) cells. In: de Serres, F.J. & Ashby, J., eds, Evaluation of Short-Term Tests for Carcinogens. Report of the International Collaborative Program (Progress in Mutation Research, Vol. 1), Amsterdam, Elsevier, pp. 551–559 156-59-2 cis-1,2-Dichloroethylene Cl/C=C\Cl negative negative in Vitro Mammalian Chromosome Aberration Test Sofuni, T., Ed. (1998). Data Book of Chromosomal Aberration Test in vitro, Revised Edition. Life-Science Information Center, Tokyo, Japan 79-34-5 1,1,2,2-Tetrachloroethane ClC(Cl)C(Cl)Cl negative negative in Vitro Mammalian Chromosome Aberration Test NTP Technical Report on the Toxicity Studies of 1,1,2,2-Tetrachloroethane (CAS No. 79-34-5) Administered in Microcapsules in Feed to F344/N Rats and B6C3F1 Mice, March 2004; https://ntp.niehs.nih.gov/ntp/htdocs/st_rpts/tox049.pdf