CAS	Chem.name	Chem.SMILES	#CA_without_S9	#Obs_CA_with_S9	Bioassay - 	Reference(s) -
584-84-9	Toluene 2,4-diisocyanate	Cc1ccc(N=C=O)cc1N=C=O	negative	negative	in Vitro Mammalian Chromosome Aberration Test 	GULATI,DK. et al; CHROMOSOME ABERRATION AND SISTER CHROMATID EXCHANGE TESTS IN CHINESE HAMSTER OVARY CELLS IN VITRO. III: RESULTS WITH 27 CHEMICALS; ENVIRON. MOL. MUTAGEN. 13(2):133-193, 1989
101-68-8	4,4'-diphenylmethane diisocyanate	O=C=Nc1ccc(Cc2ccc(N=C=O)cc2)cc1	negative	positive	in Vitro Mammalian Chromosome Aberration Test 	Sofuni, T., Ed. (1998). Data Book of Chromosomal Aberration Test in vitro, Revised Edition. Life-Science Information Center, Tokyo, Japan
2778-42-9	1,3-Bis(1-isocyanato-1-methylethyl)benzene	CC(C)(c1cccc(C(C)(C)N=C=O)c1)N=C=O	negative	negative	in Vitro Mammalian Chromosome Aberration Test 	http://apps.echa.europa.eu/registered/data/dossiers/DISS-9ea4f857-0e7e-4de5-e044-00144f67d031/AGGR-bf6ee7e9-b870-4fd0-9657-265242b6de8f_DISS-9ea4f857-0e7e-4de5-e044-00144f67d031.html#GEN_DATA_SOURCE_HD
102-36-3	3,4-Dichlorophenyl isocyanate	O=C=Nc1ccc(Cl)c(Cl)c1	negative	negative	in Vitro Mammalian Chromosome Aberration Test 	http://apps.echa.europa.eu/registered/data/dossiers/DISS-a13473ac-d753-67db-e044-00144f67d031/AGGR-8effb176-5f7e-45aa-bbda-d8fb05fc581b_DISS-a13473ac-d753-67db-e044-00144f67d031.html#AGGR-8effb176-5f7e-45aa-bbda-d8fb05fc581b
5124-30-1	Methylene bis(4-cyclohexylisocyanate)	O=C=NC1CCC(CC2CCC(N=C=O)CC2)CC1	negative	negative	in Vitro Mammalian Chromosome Aberration Test 	http://apps.echa.europa.eu/registered/data/dossiers/DISS-9eb6a35e-0589-3c9d-e044-00144f67d031/AGGR-0b757e65-5d40-447f-98aa-2f70a53f789a_DISS-9eb6a35e-0589-3c9d-e044-00144f67d031.html#ADMIN_DATA
556-61-6	Isothiocyanatomethane	CN=C=S	positive	positive	in Vitro Mammalian Chromosome Aberration Test 	NIHS Japan
57-06-7	Allyl isothiocyanate	C=CCN=C=S	positive	positive	in Vitro Mammalian Chromosome Aberration Test 	Galloway S., M. Armstrong, et al., Environ. Mol.Mutagenesis, !0(10), 1-35, (1987)
2257-09-2	Phenethyl isothiocyanate	S=C=NCCc1ccccc1	positive	positive	in Vitro Mammalian Chromosome Aberration Test 	Musk S., T. Smith, et al., Mutation Research, 348, 19-23, (1995)
622-78-6	Benzyl isothiocyanate	S=C=NCc1ccccc1	positive	positive	in Vitro Mammalian Chromosome Aberration Test 	Musk S., S. Astley, et al., Food Chem. Toxicol., 33,(1), 31-37, (1995)
91-08-7	2,6-Toluene diisocyanate	Cc1c(N=C=O)cccc1N=C=O	positive	positive	in Vitro Mammalian Chromosome Aberration Test 	GULATI,DK.et al; III: RESULTS WITH 27 CHEMICALS; ENVIRON. MOL. MUTAGEN. 13(2):133-193, 1989; JAPAN CHEMICAL INDUSTRY ECOLOGY- TOXICOLOGY AND INFORMATION CENTER, JAPAN; MUTAGENICITY TEST DATA OF EXISTING CHEMICAL SUBSTANCES BASED ON THE TOXICITY INVESTIGATION OF THE INDUSTRIAL SAFETY AND HEALTH LAW; 1996
624-83-9	Methyl isocyanate	CN=C=O	positive	positive	in Vitro Mammalian Chromosome Aberration Test 	Mason J., E. Zeiger, et al., Environmental Mutagenesis, 9,9-18, 1987.
4098-71-9	Isophorone diisocyanate	CC1(C)CC(N=C=O)CC(C)(CN=C=O)C1	positive	positive	in Vitro Mammalian Chromosome Aberration Test 	ECHA, Exp. Key toxicity in vitro.003, report 2003.
91-97-4	Bitolylene diisocyanate	Cc1cc(-c2ccc(N=C=O)c(C)c2)ccc1N=C=O	positive	positive	in Vitro Mammalian Chromosome Aberration Test 	Japan Chemical Industry Ecology Toxicology & Information Center, Japan (JETOC), Mutagenicity Test Data of Existing Chemical Substances, 1995/12/31; Test guideline equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) and EU Method B.10 (Mutagenicity - In Vitro Mammalian Chromosome Aberration Test); http://apps.echa.europa.eu/registered/data/dossiers/DISS-9d9568c1-3c26-0b72-e044-00144f67d249/AGGR-6ce1eaf3-4cda-40c4-93ac-8c7f98960912_DISS-9d9568c1-3c26-0b72-e044-00144f67d249.html#GEN_RESULTS_HD
3173-72-6	1,5-Naphthylene di-isocyanate	O=C=Nc1cccc2c1cccc2N=C=O	positive	positive	in Vitro Mammalian Chromosome Aberration Test 	http://apps.echa.europa.eu/registered/data/dossiers/DISS-9eae8ee0-1090-7128-e044-00144f67d031/AGGR-a18c1776-bdbc-442a-9d5a-b7b4f2e04d68_DISS-9eae8ee0-1090-7128-e044-00144f67d031.html#GEN_RESULTS_HD